Comparing WP_004321164.1 NCBI__GCF_000310185.1:WP_004321164.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
2cdqA Crystal structure of arabidopsis thaliana aspartate kinase complexed with lysine and s- adenosylmethionine (see paper)
27% identity, 74% coverage: 110:455/466 of query aligns to 94:458/470 of 2cdqA
Sites not aligning to the query:
3tviE Crystal structure of clostridium acetobutylicum aspartate kinase (caak): an important allosteric enzyme for industrial amino acids production (see paper)
24% identity, 70% coverage: 131:455/466 of query aligns to 106:436/439 of 3tviE
Sites not aligning to the query:
3c1nA Crystal structure of allosteric inhibition threonine-sensitive aspartokinase from methanococcus jannaschii with l-threonine (see paper)
25% identity, 97% coverage: 3:455/466 of query aligns to 2:456/458 of 3c1nA
2hmfA Structure of a threonine sensitive aspartokinase from methanococcus jannaschii complexed with mg-adp and aspartate (see paper)
25% identity, 95% coverage: 3:443/466 of query aligns to 2:449/464 of 2hmfA
O81852 Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; AK-HD 2; AK-HSDH 2; Beta-aspartyl phosphate homoserine 2; EC 2.7.2.4; EC 1.1.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
28% identity, 57% coverage: 190:454/466 of query aligns to 269:549/916 of O81852
3c1mC Cyrstal structure of threonine-sensitive aspartokinase from methanococcus jannaschii with mgamp-pnp and l-aspartate (see paper)
25% identity, 95% coverage: 3:443/466 of query aligns to 2:453/468 of 3c1mC
O60163 Probable aspartokinase; Aspartate kinase; EC 2.7.2.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 74% coverage: 106:452/466 of query aligns to 119:488/519 of O60163
3tviA Crystal structure of clostridium acetobutylicum aspartate kinase (caak): an important allosteric enzyme for industrial amino acids production (see paper)
24% identity, 57% coverage: 190:455/466 of query aligns to 159:428/429 of 3tviA
Sites not aligning to the query:
3l76A Crystal structure of aspartate kinase from synechocystis (see paper)
25% identity, 48% coverage: 240:462/466 of query aligns to 170:411/585 of 3l76A
Sites not aligning to the query:
P08660 Lysine-sensitive aspartokinase 3; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase III; EC 2.7.2.4 from Escherichia coli (strain K12) (see paper)
23% identity, 97% coverage: 2:455/466 of query aligns to 4:447/449 of P08660
2j0xA Crystal structure of e. Coli aspartokinase iii in complex with lysine and aspartate (t-state) (see paper)
23% identity, 97% coverage: 2:455/466 of query aligns to 2:445/447 of 2j0xA
2j0wA Crystal structure of e. Coli aspartokinase iii in complex with aspartate and adp (r-state) (see paper)
23% identity, 97% coverage: 2:455/466 of query aligns to 2:445/447 of 2j0wA
>WP_004321164.1 NCBI__GCF_000310185.1:WP_004321164.1
MISVEKIGGTSMSAFGDVLRHIMLYDKSRILGRIYVVSAYSGVTNQLLEHKKTGERGIYA
LFAEGSDYHGALDALAVSLKKLNAGFAELALPLDVADAFVDTRIGEVKKYLDAMQHVLAS
GYIRRQDVLLAAREVLASVGESHSAFNSVEILKANGVNAILLDLAGFHDDKAWTIDERIH
NSFKGLDLDNSVIVATGYTKGTEGIMREFDRGYSEVTFSKIAVEVRPAEAVIHKEFHLSS
ADPNIVGLENAVIVGATNYDVADQLADVGMEAIHPKAAKPMELAGIPIRLKNTFEPEHPG
TLITKDYVGERARVEMVTGSDKVTLVEIHDPSMVGTVGFDLGIMEIFCRHDISYILKATN
ANSIAHVLWENSVTPALIAELEARYQVVTVKNSAIVCAIGSNISIPGVLARAAQALADAQ
INVNCVSQTLRQVNMQFIIERSDYKKAIIALNHSLCVTPGVPVPRA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory