Comparing WP_005345039.1 NCBI__GCF_000173975.1:WP_005345039.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3eleA Crystal structure of amino transferase (rer070207001803) from eubacterium rectale at 2.10 a resolution
48% identity, 100% coverage: 1:393/394 of query aligns to 3:396/398 of 3eleA
1o4sB Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
30% identity, 92% coverage: 23:383/394 of query aligns to 27:375/384 of 1o4sB
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
28% identity, 92% coverage: 31:392/394 of query aligns to 23:384/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
28% identity, 92% coverage: 31:392/394 of query aligns to 23:384/388 of 1gd9A
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
29% identity, 80% coverage: 70:386/394 of query aligns to 64:378/382 of 1gc4A
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan (see paper)
29% identity, 80% coverage: 70:386/394 of query aligns to 64:378/382 of 1gc3A
Sites not aligning to the query:
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
28% identity, 80% coverage: 70:386/394 of query aligns to 64:378/382 of 1b5oA
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate (see paper)
28% identity, 80% coverage: 70:386/394 of query aligns to 64:378/382 of 1bkgA
1bjwA Aspartate aminotransferase from thermus thermophilus (see paper)
28% identity, 80% coverage: 70:386/394 of query aligns to 64:378/382 of 1bjwA
Sites not aligning to the query:
Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
28% identity, 81% coverage: 70:389/394 of query aligns to 64:381/385 of Q56232
Sites not aligning to the query:
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
26% identity, 91% coverage: 35:394/394 of query aligns to 37:399/402 of P14909
Sites not aligning to the query:
P04694 Tyrosine aminotransferase; TAT; L-tyrosine:2-oxoglutarate aminotransferase; EC 2.6.1.5 from Rattus norvegicus (Rat) (see 2 papers)
25% identity, 92% coverage: 33:393/394 of query aligns to 71:441/454 of P04694
Sites not aligning to the query:
1j32A Aspartate aminotransferase from phormidium lapideum
25% identity, 91% coverage: 26:383/394 of query aligns to 21:377/388 of 1j32A
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v (see paper)
27% identity, 91% coverage: 27:383/394 of query aligns to 23:396/402 of 5wmiA
Sites not aligning to the query:
5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
27% identity, 93% coverage: 16:383/394 of query aligns to 15:377/387 of 5yhvB
5yhvA Crystal structure of an aminotransferase from mycobacterium tuberculosis
27% identity, 93% coverage: 16:383/394 of query aligns to 22:384/394 of 5yhvA
P96847 Valine--pyruvate aminotransferase; Alanine--valine transaminase; EC 2.6.1.66 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
27% identity, 93% coverage: 16:383/394 of query aligns to 16:378/388 of P96847
5wmhA Arabidopsis thaliana prephenate aminotransferase (see paper)
27% identity, 89% coverage: 35:383/394 of query aligns to 31:396/399 of 5wmhA
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
28% identity, 97% coverage: 9:389/394 of query aligns to 1:367/370 of Q58097
5wmlA Arabidopsis thaliana prephenate aminotransferase mutant- k306a (see paper)
27% identity, 89% coverage: 35:383/394 of query aligns to 32:397/404 of 5wmlA
Sites not aligning to the query:
>WP_005345039.1 NCBI__GCF_000173975.1:WP_005345039.1
MLNKQYTSMLQEKDVIFEIFQYATERAKVVGAENIYDFSLGNPSVPAPSIVNETIVQKVN
TLDPLALHGYSPSFGIMETREKIAVFLNKKYGSSYKASNIFMAIGAAGALAHAFRAVTNP
GDEIITFAPCFSEYKPYTAGAGLKLTIIPADIDTFQINFAAFEAQLNENTTAVLINSPNN
PSGIVYSTETIKKLADILTEKSKEFGHPIYLISDEPYRDIIFEGVDAPYVANYYKNTLTC
YSFSKSISLPGERIGYLAVHPDCIEANKIIEICPQISRTIGQNGAASLMQRTVADVCNYT
SDLSVYETNKKILFEALKEYGYHCVEPGGTFYMFPRSLEPDSQAFCKKAMEKDLMLVPGD
IFGCPGHFRIAYCVPTERVEKALPIFQELAEEYL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory