SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_005453415.1 NCBI__GCF_000244975.1:WP_005453415.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

P9WIC1 Intracellular chorismate mutase; CM; EC 5.4.99.5 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
71% identity, 67% coverage: 21:86/98 of query aligns to 28:93/105 of P9WIC1

query
sites
P9WIC1
E
 
E
I
 
I
D
 
D
Q
 
T
L
 
L
R
 
R
K
 
E
E
 
E
I
 
I
D
 
D
W
 
R
L
 
L
D
 
D
A
 
A
E
 
E
I
 
I
L
 
L
R
 
A
L
 
L
V
 
V
K
 
K
R
 
R
R
 
R
A
 
A
E
 
E
V
 
V
S
 
S
K
 
K
T
 
A
I
 
I
G
 
G
A
 
K
A
 
A
R
|
R
M
 
M
A
 
A
A
 
S
G
 
G
G
 
G
P
 
T
R
 
R
I
 
L
V
 
V
Y
 
H
N
 
S
R
 
R
E
 
E
M
 
M
D
 
K
V
 
V
L
 
I
A
 
E
R
 
R
Y
 
Y
R
 
S
E
 
E
L
 
L
G
 
G
P
 
P
E
 
D
G
 
G
R
 
K
Q
 
D
L
 
L
A
 
A
M
 
I

Sites not aligning to the query:

5ckxD Non-covalent complex of dahp synthase and chorismate mutase from mycobacterium tuberculosis with bound transition state analog and feedback effectors tyrosine and phenylalanine (see paper)
71% identity, 67% coverage: 21:86/98 of query aligns to 2:67/79 of 5ckxD

query
sites
5ckxD
E
 
E
I
 
I
D
 
D
Q
 
T
L
 
L
R
 
R
K
 
E
E
 
E
I
 
I
D
 
D
W
 
R
L
 
L
D
 
D
A
 
A
E
 
E
I
 
I
L
 
L
R
 
A
L
 
L
V
 
V
K
 
K
R
 
R
R
|
R
A
 
A
E
 
E
V
 
V
S
|
S
K
 
K
T
 
A
I
|
I
G
 
G
A
 
K
A
 
A
R
|
R
M
 
M
A
 
A
A
 
S
G
 
G
G
 
G
P
 
T
R
 
R
I
 
L
V
 
V
Y
 
H
N
 
S
R
|
R
E
|
E
M
 
M
D
 
K
V
 
V
L
 
I
A
 
E
R
 
R
Y
 
Y
R
 
S
E
 
E
L
 
L
G
 
G
P
 
P
E
 
D
G
 
G
R
 
K
Q
 
D
L
 
L
A
 
A
M
 
I

Sites not aligning to the query:

5hudE Non-covalent complex of and dahp synthase and chorismate mutase from corynebacterium glutamicum with bound transition state analog (see paper)
51% identity, 79% coverage: 21:97/98 of query aligns to 7:84/84 of 5hudE

query
sites
5hudE
E
 
E
I
 
I
D
 
Q
Q
 
K
L
 
Y
R
 
R
K
 
E
E
 
E
I
 
I
D
 
N
W
 
R
L
 
L
D
 
D
A
 
R
E
 
E
I
 
I
L
 
L
R
 
D
L
 
A
V
 
V
K
 
K
R
 
R
R
|
R
A
 
T
E
 
K
V
 
I
S
|
S
K
 
Q
T
 
T
I
|
I
G
 
G
A
 
K
A
 
T
R
|
R
M
 
M
A
 
S
A
 
S
G
 
G
G
 
G
P
 
T
R
 
R
I
x
L
V
|
V
Y
 
H
N
 
T
R
|
R
E
|
E
M
 
V
D
 
A
V
 
I
L
 
I
A
 
N
R
 
Q
Y
 
F
R
 
R
-
 
E
E
 
E
L
 
I
G
 
G
P
 
E
E
 
E
G
 
G
R
 
P
Q
 
A
L
 
L
A
 
A
M
 
G
A
 
I
L
 
L
L
|
L
N
 
R
L
 
M
G
 
G
R
 
R
G
 
G
R
 
K
L
 
L
G
 
G

Query Sequence

>WP_005453415.1 NCBI__GCF_000244975.1:WP_005453415.1
MNAQTHDTDEAGRSGATTAEEIDQLRKEIDWLDAEILRLVKRRAEVSKTIGAARMAAGGP
RIVYNREMDVLARYRELGPEGRQLAMALLNLGRGRLGR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory