Comparing WP_005456405.1 NCBI__GCF_000244975.1:WP_005456405.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
27% identity, 90% coverage: 46:434/434 of query aligns to 88:490/503 of Q8C165
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
29% identity, 90% coverage: 6:396/434 of query aligns to 13:365/408 of Q03154
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
28% identity, 90% coverage: 6:396/434 of query aligns to 13:364/407 of P37111
Sites not aligning to the query:
1q7lA Zn-binding domain of the t347g mutant of human aminoacylase-i (see paper)
36% identity, 36% coverage: 6:163/434 of query aligns to 7:160/192 of 1q7lA
Sites not aligning to the query:
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
31% identity, 33% coverage: 72:214/434 of query aligns to 73:195/381 of 8uw6B
Sites not aligning to the query:
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
23% identity, 95% coverage: 6:419/434 of query aligns to 11:366/383 of 7uoiA
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
31% identity, 25% coverage: 41:150/434 of query aligns to 22:141/377 of P44514
Sites not aligning to the query:
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
35% identity, 19% coverage: 70:150/434 of query aligns to 64:145/380 of 5vo3A
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
35% identity, 19% coverage: 70:150/434 of query aligns to 62:143/258 of 4h2kA
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
35% identity, 22% coverage: 27:121/434 of query aligns to 42:136/458 of 2pokA
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
29% identity, 38% coverage: 72:236/434 of query aligns to 99:243/426 of 3pfoA
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
38% identity, 17% coverage: 70:144/434 of query aligns to 60:135/265 of 4op4B
Sites not aligning to the query:
7lgpB Dape enzyme from shigella flexneri
30% identity, 38% coverage: 72:237/434 of query aligns to 63:221/377 of 7lgpB
1lfwA Crystal structure of pepv (see paper)
35% identity, 20% coverage: 72:159/434 of query aligns to 82:168/468 of 1lfwA
Sites not aligning to the query:
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
35% identity, 20% coverage: 72:159/434 of query aligns to 82:168/470 of P45494
Sites not aligning to the query:
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
35% identity, 17% coverage: 70:144/434 of query aligns to 60:135/377 of 7t1qA
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
30% identity, 39% coverage: 70:237/434 of query aligns to 60:220/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
30% identity, 39% coverage: 70:237/434 of query aligns to 60:220/375 of 4pqaA
Sites not aligning to the query:
3dljA Crystal structure of human carnosine dipeptidase 1
34% identity, 21% coverage: 35:125/434 of query aligns to 59:147/471 of 3dljA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
41% identity, 14% coverage: 64:125/434 of query aligns to 119:178/507 of Q96KN2
Sites not aligning to the query:
>WP_005456405.1 NCBI__GCF_000244975.1:WP_005456405.1
MTADVVDLCAQLIRIDTTNHGAGDARGEREAAEFCGTTLADAGLQPTILESAPRRANVVT
RVPGDNPDLPPLLIQGHLDVVPADAGEWTVDPFSGTVADGYVWGRGAVDMKDFCATVLAA
VHSLATTGRRPRRDIVLAFVADEEDRGEHGAHWLTTHHPDLFADCAAAISESGGYTYHVR
ATDGRKIRLYPIGTAERGTAHLKLTARGRAGHGSRRNDANAVTRLVTALHALAAHDWPVV
LTPTVEAFLQRTGKALGVDIDLHDIDTTLDRLGDAAPLVESTVRNSVTPTVLTAGYKVNV
IPGTAEARVDGRVLPGTEDTLLSQVDALIGPDVEREFLSRSLPVQAPVDSPWFDAMSNAL
HSQDPDAVVVPYCLGGGTDAKAFSQLGIDCYGFAPLWLPEGFDYRAMAHGVDERVPVEGL
RFGTRVLEHLLLHA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory