Comparing WP_005457821.1 NCBI__GCF_000244975.1:WP_005457821.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis (see paper)
60% identity, 84% coverage: 17:303/341 of query aligns to 8:294/296 of 1xxxA
P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
60% identity, 84% coverage: 17:303/341 of query aligns to 12:298/300 of P9WP25
5j5dA Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
60% identity, 84% coverage: 17:303/341 of query aligns to 9:295/297 of 5j5dA
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
60% identity, 84% coverage: 17:303/341 of query aligns to 7:293/295 of 3l21B
5ktlA Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
42% identity, 82% coverage: 17:294/341 of query aligns to 5:285/295 of 5ktlA
5ud6C Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
43% identity, 82% coverage: 17:294/341 of query aligns to 4:292/299 of 5ud6C
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
36% identity, 81% coverage: 19:294/341 of query aligns to 9:286/307 of 4fhaA
Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
35% identity, 84% coverage: 17:303/341 of query aligns to 2:293/294 of Q9X1K9
1o5kA Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
35% identity, 84% coverage: 17:303/341 of query aligns to 3:294/295 of 1o5kA
4i7wA Agrobacterium tumefaciens dhdps with lysine and pyruvate
38% identity, 84% coverage: 17:303/341 of query aligns to 2:292/294 of 4i7wA
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
38% identity, 84% coverage: 17:303/341 of query aligns to 2:292/294 of Q8UGL3
Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
35% identity, 85% coverage: 17:305/341 of query aligns to 2:292/292 of Q07607
3di1B Crystal structure of the staphylococcus aureus dihydrodipicolinate synthase-pyruvate complex (see paper)
38% identity, 65% coverage: 17:237/341 of query aligns to 5:227/291 of 3di1B
Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain COL) (see paper)
38% identity, 65% coverage: 17:237/341 of query aligns to 5:227/295 of Q5HG25
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
33% identity, 83% coverage: 21:303/341 of query aligns to 6:290/291 of 4dxvA
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
33% identity, 83% coverage: 21:303/341 of query aligns to 6:290/291 of 3u8gA
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
33% identity, 83% coverage: 21:303/341 of query aligns to 6:290/291 of 3tdfA
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
33% identity, 83% coverage: 21:303/341 of query aligns to 6:290/291 of 3tceA
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
33% identity, 83% coverage: 21:303/341 of query aligns to 6:290/291 of 3rk8A
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
33% identity, 83% coverage: 21:303/341 of query aligns to 6:290/291 of 3pueB
>WP_005457821.1 NCBI__GCF_000244975.1:WP_005457821.1
MSIAPPTPPTAAPGRPFGRVLTAMVTPFTAEGAVDLKRAQELAVHLVELGNDGLVVNGTT
GESPTTTDAEKADLVRAVVEAVGDRATVVAGAGTNNTTHSVEMAKQAEKSGAHGLLVVTP
YYSRPTQAGLYAHFTTVADATELPVMLYDIPPRSIVPIEVDTLRRLAEHPRVLAVKDAKG
DLLAGSEVIANTHLAYYSGDDGLNLPWLSVGATGVVSVIGHVVAGRIRAMIDAYEDGDTS
TARTNHRGMIPVYRAFSRVGGVVFAKTALRLRGMDVGEPRLPMVSAPEELVRAIADDLTQ
AGVPLETSPAGDWAGSRVAQADSAAAYVTPTTHTSVGTIQR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory