Comparing WP_005812354.1 NCBI__GCF_000021925.1:WP_005812354.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3o6xA Crystal structure of the type iii glutamine synthetase from bacteroides fragilis (see paper)
40% identity, 100% coverage: 2:695/697 of query aligns to 27:637/638 of 3o6xA
P0A9C5 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Escherichia coli (strain K12) (see 3 papers)
36% identity, 16% coverage: 246:355/697 of query aligns to 195:304/469 of P0A9C5
Sites not aligning to the query:
7tenA Glutamine synthetase (see paper)
36% identity, 12% coverage: 245:330/697 of query aligns to 168:253/442 of 7tenA
Sites not aligning to the query:
7tf9S L. Monocytogenes gs(14)-q-glnr peptide (see paper)
36% identity, 12% coverage: 245:330/697 of query aligns to 169:254/443 of 7tf9S
Sites not aligning to the query:
7tfaB Glutamine synthetase (see paper)
37% identity, 12% coverage: 245:328/697 of query aligns to 167:250/441 of 7tfaB
Sites not aligning to the query:
7tdpA Structure of paenibacillus polymyxa gs bound to met-sox-p-adp (transition state complex) to 1.98 angstom (see paper)
37% identity, 12% coverage: 245:328/697 of query aligns to 165:248/439 of 7tdpA
Sites not aligning to the query:
P0A1P6 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I beta; GSI beta; EC 6.3.1.2 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
34% identity, 16% coverage: 246:355/697 of query aligns to 195:304/469 of P0A1P6
Sites not aligning to the query:
2lgsA Feedback inhibition of fully unadenylylated glutamine synthetase from salmonella typhimurium by glycine, alanine, and serine (see paper)
34% identity, 16% coverage: 246:355/697 of query aligns to 188:297/445 of 2lgsA
Sites not aligning to the query:
1lgrA Interactions of nucleotides with fully unadenylylated glutamine synthetase from salmonella typhimurium (see paper)
34% identity, 16% coverage: 246:355/697 of query aligns to 188:297/445 of 1lgrA
Sites not aligning to the query:
1fpyA Crystal structure of glutamine synthetase from salmonella typhimurium with inhibitor phosphinothricin (see paper)
34% identity, 16% coverage: 246:355/697 of query aligns to 194:303/468 of 1fpyA
Sites not aligning to the query:
1f1hA Crystal structure of glutamine synthetase from salmonella typhimurium with thallium ions (see paper)
34% identity, 16% coverage: 246:355/697 of query aligns to 194:303/468 of 1f1hA
Sites not aligning to the query:
P12425 Glutamine synthetase; GS; Glutamate--ammonia ligase; Glutamine synthetase I alpha; GSI alpha; EC 6.3.1.2 from Bacillus subtilis (strain 168) (see 5 papers)
36% identity, 13% coverage: 245:332/697 of query aligns to 170:256/444 of P12425
Sites not aligning to the query:
4lnkA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of gs-glutamate-amppcp complex (see paper)
36% identity, 13% coverage: 245:332/697 of query aligns to 169:255/443 of 4lnkA
Sites not aligning to the query:
4lniA B. Subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex (see paper)
36% identity, 13% coverage: 245:332/697 of query aligns to 169:255/443 of 4lniA
Sites not aligning to the query:
4s0rD Structure of gs-tnra complex (see paper)
36% identity, 13% coverage: 245:332/697 of query aligns to 173:259/447 of 4s0rD
Sites not aligning to the query:
7tdvC Glutamine synthetase (see paper)
36% identity, 12% coverage: 245:325/697 of query aligns to 169:249/443 of 7tdvC
Sites not aligning to the query:
7tf6A Glutamine synthetase (see paper)
36% identity, 12% coverage: 245:325/697 of query aligns to 164:244/438 of 7tf6A
Sites not aligning to the query:
8oooA Glutamine synthetase from methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and mgatp at 2.15 a resolution (see paper)
27% identity, 20% coverage: 190:325/697 of query aligns to 133:254/447 of 8oooA
Sites not aligning to the query:
8ooqB Glutamine synthetase from Methanothermococcus thermolithotrophicus (see paper)
27% identity, 20% coverage: 190:325/697 of query aligns to 132:253/446 of 8ooqB
Sites not aligning to the query:
8tfkA Glutamine synthetase (see paper)
28% identity, 18% coverage: 238:360/697 of query aligns to 159:281/440 of 8tfkA
Sites not aligning to the query:
>WP_005812354.1 NCBI__GCF_000021925.1:WP_005812354.1
MDFFGKNVFNDAVMRERLPKNTYKALHKTIDEGLPLQLEVAEVVANAMKDWAIENGATHY
THWFQPMTGFTAEKHDSFISPTSDGKVIMEFSGKELIKGEPDASSFPNGGIRSTFEARGY
TAWDCTSPAFLREDAGKVILCIPTAFCSYTGEALDKKTPLLRSMETISKQALRILRLFGN
TTAKRVTPTVGAEQEYFLIEKKYHQKRLDLMLTGRTLFGVLPPKGQEMEDHYFGIINERV
TAFMQEVNIELWKLGVLAKTQHKEAAPGQYEIAPIFTSTNIATDHNQIIMDTLHKVANRH
GLACLLHEKPFAGVNGSGKHNNWSLSTDEGVNLLEPGKTPHENAQFLTFICAVIKAVDEY
ADLLRASAANSGNDHRLGANEAPPAIISIFLGDELSDIIEQLKNGKPNSSKQGGELTIGV
STLPSLPKDSTDRNRTSPFAFTGNKFEFRMVPSSLSIAGPNVVINTIVAEVLSQMADRLE
KAEDFHGELQAILQEIAIHHSRVVFDGNGYSEEWVKEAARRGLPNLSSTVEAISALISEK
TIELFKHHGVFSATELHSRYEIYLEQYSKTINIEALTMVDVAKRQILPAVMRYSTELAHS
INTIRTADPEAEVLAQRSLLNEISPLLKELSFKTKALQDATCAAKQLHGDAYKQGIYYRD
VVFKAMNELRQTADQLEVLVDYDMWPLPSYTKMLFRL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory