Comparing WP_007690519.1 NCBI__GCF_000336675.1:WP_007690519.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
O06724 Oxaloacetate tautomerase YisK; Oxaloacetate decarboxylase YisK; EC 5.3.2.2; EC 4.1.1.112 from Bacillus subtilis (strain 168) (see paper)
43% identity, 90% coverage: 24:241/242 of query aligns to 70:301/301 of O06724
Sites not aligning to the query:
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
43% identity, 90% coverage: 24:241/242 of query aligns to 71:302/303 of 8sutA
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
43% identity, 90% coverage: 24:241/242 of query aligns to 70:301/303 of 8skyB
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
44% identity, 93% coverage: 16:240/242 of query aligns to 35:266/269 of 4dbhA
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
40% identity, 94% coverage: 16:242/242 of query aligns to 39:249/252 of 3qdfA
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
42% identity, 81% coverage: 45:241/242 of query aligns to 72:279/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
42% identity, 81% coverage: 45:241/242 of query aligns to 72:279/290 of 8gsrA
Q1NEI7 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase; L-2,4-diketo-3-deoxyrhamnonate hydrolase; L-DKDR hydrolase; SpLRA6; EC 3.7.1.26 from Sphingomonas sp. (strain SKA58) (see paper)
41% identity, 81% coverage: 45:241/242 of query aligns to 67:274/285 of Q1NEI7
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
41% identity, 85% coverage: 34:238/242 of query aligns to 59:274/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
41% identity, 85% coverage: 34:238/242 of query aligns to 59:274/280 of 6j5xA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
39% identity, 86% coverage: 33:240/242 of query aligns to 57:274/277 of 6iymA
P76004 Oxaloacetate tautomerase YcgM; EC 5.3.2.2 from Escherichia coli (strain K12)
38% identity, 78% coverage: 44:232/242 of query aligns to 17:211/219 of P76004
Q6P587 Oxaloacetate tautomerase FAHD1, mitochondrial; Acylpyruvase FAHD1; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; ODx; YisK-like protein; EC 5.3.2.2; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 4 papers)
36% identity, 81% coverage: 46:242/242 of query aligns to 17:218/221 of Q6P587
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
36% identity, 81% coverage: 46:242/242 of query aligns to 15:216/218 of 6fogA
Sites not aligning to the query:
Q8R0F8 Oxaloacetate tautomerase FAHD1, mitochondrial; Acylpyruvase FAHD1; Acylpyruvate hydrolase; ApH; Fumarylacetoacetate hydrolase domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; ODx; EC 5.3.2.2; EC 3.7.1.5; EC 4.1.1.112 from Mus musculus (Mouse) (see paper)
36% identity, 81% coverage: 46:242/242 of query aligns to 17:218/221 of Q8R0F8
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
36% identity, 81% coverage: 46:242/242 of query aligns to 14:215/216 of 6sbiA
3v77A Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from oleispira antarctica (see paper)
38% identity, 79% coverage: 40:230/242 of query aligns to 12:209/224 of 3v77A
1gttA Crystal structure of hpce (see paper)
42% identity, 71% coverage: 46:218/242 of query aligns to 225:392/421 of 1gttA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
38% identity, 79% coverage: 43:234/242 of query aligns to 69:269/279 of 6v77B
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
38% identity, 80% coverage: 43:236/242 of query aligns to 76:256/264 of 6jvwB
>WP_007690519.1 NCBI__GCF_000336675.1:WP_007690519.1
MATMRFRDPAGSIRTGTPTDDGVEFGDESYALDEVDVLAPCDPSKIVCIGLNYADHAEEE
GMDLPDRPLLFLKPPNAVSGHGDTVTLPEGKEKVEHEAELAVVIGEQCRNVAADDAMDVV
AGFTCADDVSNRDDQRVEQNWVRGKAFDNACPLGPVLADPEDVPDDASVELRLNGETVQS
SSRAEFVFSVPELIEEITQYMTLEAGDVIITGTPAGVGELEDGDEVEVEVEGVGTLEHTV
AR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory