SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_007692944.1 NCBI__GCF_000336675.1:WP_007692944.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 5 hits to proteins with known functional sites (download)

8iyoD Crystal structure of a protein acetyltransferase, hp0935, acetyl-coa bound form
27% identity, 55% coverage: 83:185/187 of query aligns to 60:163/163 of 8iyoD

query
sites
8iyoD
D
 
E
G
 
G
E
 
N
E
 
K
V
 
L
V
 
I
G
 
G
C
 
I
V
 
C
Y
 
G
L
 
L
Y
 
N
D
 
P
L
 
I
P
 
N
E
 
Q
N
 
T
E
 
E
A
 
A
E
 
E
V
x
L
K
x
C
R
 
K
L
x
F
Y
 
H
V
x
I
R
 
N
E
 
S
A
 
A
Y
 
Y
R
x
Q
G
x
S
R
 
Q
G
|
G
L
 
L
G
|
G
R
x
Q
R
 
K
L
 
L
L
 
Y
E
 
E
R
 
S
L
 
V
V
 
E
E
 
K
A
 
Y
A
 
A
E
 
F
R
 
I
D
 
K
G
 
G
Y
 
Y
D
 
T
S
 
K
L
 
I
R
 
S
L
 
L
D
 
H
T
x
V
A
 
S
P
 
K
Y
 
S
M
x
Q
E
 
I
R
x
K
A
|
A
Q
 
C
Q
x
N
L
|
L
Y
|
Y
R
 
Q
D
x
K
L
 
L
G
 
G
F
 
F
D
 
V
T
 
H
Y
 
I
E
 
K
G
 
E
G
 
E
E
 
D
S
 
C
V
 
V
T
 
V
D
 
E
V
 
L
-
 
G
P
 
E
D
 
E
P
 
T
L
 
L
L
 
I
D
 
F
D
 
P
L
 
T
V
 
L
F
 
F
M
 
M
R
 
E
R
 
K
R
 
I
L
 
L
D
 
S

3d8pA Crystal structure of acetyltransferase of gnat family (np_373092.1) from staphylococcus aureus mu50 at 2.20 a resolution
25% identity, 82% coverage: 30:182/187 of query aligns to 6:156/158 of 3d8pA

query
sites
3d8pA
E
 
E
Y
 
Y
H
 
N
R
 
R
S
 
S
V
 
Y
A
 
K
A
 
E
D
 
E
H
 
L
R
 
I
D
 
E
F
 
F
-
 
I
L
 
L
A
 
S
R
 
I
H
 
Q
A
 
K
T
 
N
G
 
E
Y
 
F
D
 
N
F
 
I
S
 
K
P
 
I
A
x
D
E
 
R
Y
x
D
V
x
D
Q
 
Q
H
 
P
E
 
D
L
 
L
E
 
E
K
 
N
-
 
I
D
 
E
R
 
H
S
 
N
Y
 
Y
L
 
L
R
 
-
E
 
-
N
 
N
D
 
S
G
 
G
R
 
G
R
 
Q
P
 
F
L
 
W
V
 
L
V
 
A
A
 
I
V
 
N
D
 
N
G
 
H
E
 
Q
E
 
N
V
 
I
V
 
V
G
 
G
C
 
T
V
 
I
Y
 
G
L
 
L
Y
 
I
D
 
R
L
 
L
P
 
D
E
 
N
N
 
N
E
 
M
A
 
S
E
 
A
V
 
L
K
 
K
R
 
K
L
 
M
Y
 
F
V
 
V
R
 
D
E
 
K
A
 
G
Y
 
Y
R
 
R
G
 
N
R
 
L
G
 
K
L
 
I
G
 
G
R
 
K
R
 
K
L
 
L
L
 
L
E
 
D
R
 
K
L
 
V
V
 
I
E
 
M
A
 
T
A
 
C
E
 
K
R
 
E
D
 
Q
G
 
N
Y
 
I
D
 
D
S
 
G
L
 
I
R
 
Y
L
 
L
D
 
G
T
 
T
A
 
I
P
 
D
Y
 
K
M
 
F
E
 
I
R
 
S
A
 
A
Q
 
Q
Q
 
Y
L
 
F
Y
 
Y
R
 
S
D
 
N
L
 
N
G
 
G
F
 
F
D
 
R
T
 
E
Y
 
I
E
 
K
G
 
R
G
 
G
E
 
-
S
 
-
V
 
-
T
 
-
D
 
D
V
 
L
P
 
P
D
 
S
-
 
S
-
 
F
P
 
P
L
 
K
L
 
L
D
 
D
D
 
N
L
 
R
V
 
F
F
 
Y
M
 
Y
R
 
R
R
 
N

6ao7A Crystal structure of a gnat family acetyltransferase from elizabethkingia anophelis with acetyl-coa bound (see paper)
29% identity, 43% coverage: 78:157/187 of query aligns to 39:118/153 of 6ao7A

query
sites
6ao7A
L
 
L
V
 
Y
V
 
L
A
 
A
V
 
K
D
 
Y
G
 
N
E
 
N
E
 
E
V
 
I
V
 
I
G
 
G
C
 
C
V
 
Y
Y
 
V
L
 
L
Y
 
Y
D
 
P
L
 
W
P
 
D
E
 
F
N
 
E
E
 
T
A
 
T
E
 
E
V
 
I
K
|
K
R
x
N
L
x
I
Y
x
A
V
|
V
R
 
A
E
 
E
A
 
K
Y
 
F
R
x
Q
G
x
N
R
 
Q
G
|
G
L
 
I
G
|
G
R
 
G
R
 
Q
L
 
L
L
 
L
E
 
K
R
 
D
L
 
V
V
 
I
E
 
L
A
 
K
A
 
A
E
 
K
R
 
N
D
 
K
G
 
F
Y
 
Y
D
 
K
S
 
K
L
 
L
R
 
V
L
 
I
D
x
G
T
 
T
A
 
G
P
 
N
Y
 
S
M
 
S
E
 
T
R
x
G
A
x
Q
Q
 
L
Q
x
Y
L
|
L
Y
 
Y
R
 
Q
D
x
K
L
 
Y
G
 
G
F
 
F

Sites not aligning to the query:

Q96F10 Thialysine N-epsilon-acetyltransferase; Diamine acetyltransferase 2; Spermidine/spermine N(1)-acetyltransferase 2; SSAT-2; EC 2.3.1.-; EC 2.3.1.57 from Homo sapiens (Human) (see paper)
35% identity, 27% coverage: 106:156/187 of query aligns to 94:144/170 of Q96F10

query
sites
Q96F10
L
x
I
Y
|
Y
V
|
V
R
 
M
E
 
P
A
 
E
Y
 
Y
R
 
R
G
|
G
R
x
Q
G
|
G
L
x
I
G
|
G
R
x
S
R
 
K
L
 
I
L
 
I
E
 
K
R
 
K
L
 
V
V
 
A
E
 
E
A
 
V
A
 
A
E
 
L
R
 
D
D
 
K
G
 
G
Y
 
C
D
 
S
S
 
Q
L
 
F
R
 
R
L
 
L
D
 
A
T
 
V
A
 
L
P
 
D
Y
 
W
M
x
N
E
x
Q
R
|
R
A
 
A
Q
 
M
Q
 
D
L
 
L
Y
|
Y
R
 
K
D
 
A
L
 
L
G
 
G

2beiA X-ray structure of thialysine n-acetyltransferase (ssat2) from homo sapiens (see paper)
35% identity, 27% coverage: 106:156/187 of query aligns to 81:131/156 of 2beiA

query
sites
2beiA
L
x
I
Y
|
Y
V
 
V
R
 
M
E
 
P
A
 
E
Y
 
Y
R
|
R
G
|
G
R
 
Q
G
|
G
L
 
I
G
|
G
R
x
S
R
 
K
L
 
I
L
 
I
E
 
K
R
 
K
L
 
V
V
 
A
E
 
E
A
 
V
A
 
A
E
 
L
R
 
D
D
 
K
G
 
G
Y
 
C
D
 
S
S
 
Q
L
 
F
R
 
R
L
 
L
D
x
A
T
x
V
A
 
L
P
 
D
Y
 
W
M
 
N
E
 
Q
R
|
R
A
 
A
Q
 
M
Q
 
D
L
|
L
Y
|
Y
R
 
K
D
 
A
L
 
L
G
 
G

Sites not aligning to the query:

Query Sequence

>WP_007692944.1 NCBI__GCF_000336675.1:WP_007692944.1
MAVTGNEGGVSVERSRFDTDETGIETLLREYHRSVAADHRDFLARHATGYDFSPAEYVQH
ELEKDRSYLRENDGRRPLVVAVDGEEVVGCVYLYDLPENEAEVKRLYVREAYRGRGLGRR
LLERLVEAAERDGYDSLRLDTAPYMERAQQLYRDLGFDTYEGGESVTDVPDPLLDDLVFM
RRRLDGQ

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory