SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_008507762.1 NCBI__GCF_000182725.1:WP_008507762.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 5 hits to proteins with known functional sites (download)

7bywA Crystal structure of acidovorax avenae l-fucose mutarotase (l-fucose- bound form) (see paper)
62% identity, 95% coverage: 7:114/114 of query aligns to 1:108/108 of 7bywA

query
sites
7bywA
Q
 
Q
R
 
R
M
 
M
G
 
G
M
 
M
V
 
V
I
 
I
G
 
G
L
 
I
N
 
K
P
 
P
E
 
E
K
 
H
V
 
I
A
 
D
K
 
E
Y
|
Y
K
 
K
A
 
R
L
 
L
H
|
H
A
 
A
Q
 
A
V
 
V
W
 
W
P
 
P
E
 
A
I
 
V
L
 
L
A
 
A
L
 
R
I
 
L
S
 
A
E
 
E
C
 
A
N
 
H
I
 
V
A
 
R
N
 
N
Y
|
Y
S
 
S
I
 
I
F
 
F
L
 
L
K
 
R
E
 
E
P
 
P
E
 
E
N
 
N
L
 
L
L
 
L
F
 
F
G
 
G
Y
 
Y
W
 
W
E
 
E
Y
 
Y
V
 
H
G
 
G
S
 
T
D
 
D
F
 
Y
A
 
A
A
 
A
D
 
D
M
 
M
R
 
E
K
 
A
M
 
I
A
 
A
E
 
Q
S
 
D
P
 
P
K
 
E
N
 
T
Q
 
R
E
 
R
W
|
W
W
|
W
S
 
T
V
 
F
C
 
C
M
 
G
P
 
P
C
 
C
Q
 
Q
K
 
E
P
 
P
L
 
L
E
 
A
T
 
S
R
 
R
K
 
Q
E
 
P
G
 
G
E
 
E
W
 
H
W
 
W
A
 
A
M
 
H
M
 
M
E
 
E
E
 
E
V
 
V
F
 
F
H
 
H
H
 
V
D
 
D

2qlxA Crystal structure of rhamnose mutarotase rhau of rhizobium leguminosarum in complex with l-rhamnose (see paper)
31% identity, 63% coverage: 15:86/114 of query aligns to 14:82/108 of 2qlxA

query
sites
2qlxA
L
 
L
N
 
N
P
 
P
E
 
G
K
 
M
V
 
E
A
 
A
K
 
E
Y
|
Y
K
 
R
A
 
K
L
 
R
H
|
H
A
 
D
Q
 
E
V
 
I
W
 
W
P
 
P
E
 
E
I
 
L
L
 
V
A
 
D
L
 
L
I
 
L
S
 
H
E
 
Q
C
 
S
N
 
G
I
 
A
A
 
S
N
 
D
Y
|
Y
S
 
S
I
 
I
F
 
H
L
 
L
K
 
D
E
 
R
P
 
E
E
 
T
N
 
N
L
 
T
L
 
L
F
 
F
G
 
G
Y
 
V
W
 
L
E
 
T
Y
 
R
V
 
P
G
 
K
S
 
D
D
 
-
F
 
-
A
 
-
A
 
H
D
 
T
M
 
M
R
 
A
K
 
S
M
 
L
A
 
P
E
 
D
S
 
H
P
 
P
K
 
V
N
 
M
Q
 
K
E
 
K
W
|
W
W
|
W
S
 
A

Sites not aligning to the query:

2qlwB Crystal structure of rhamnose mutarotase rhau of rhizobium leguminosarum (see paper)
31% identity, 63% coverage: 15:86/114 of query aligns to 14:82/108 of 2qlwB

query
sites
2qlwB
L
 
L
N
 
N
P
 
P
E
 
G
K
 
M
V
 
E
A
 
A
K
 
E
Y
 
Y
K
 
R
A
 
K
L
 
R
H
 
H
A
 
D
Q
 
E
V
 
I
W
 
W
P
 
P
E
 
E
I
 
L
L
 
V
A
 
D
L
 
L
I
 
L
S
 
H
E
 
Q
C
 
S
N
 
G
I
 
A
A
 
S
N
 
D
Y
 
Y
S
 
S
I
 
I
F
 
H
L
 
L
K
 
D
E
 
R
P
 
E
E
 
T
N
 
N
L
 
T
L
 
L
F
 
F
G
 
G
Y
 
V
W
 
L
E
 
T
Y
 
R
V
 
P
G
 
K
S
 
D
D
 
-
F
 
-
A
 
-
A
 
H
D
 
T
M
 
M
R
 
A
K
 
S
M
 
L
A
 
P
E
 
D
S
 
H
P
 
P
K
 
V
N
 
M
Q
 
K
E
 
K
W
 
W
W
 
W
S
 
A

Sites not aligning to the query:

1x8dA Crystal structure of e. Coli yiil protein containing l-rhamnose (see paper)
35% identity, 46% coverage: 8:59/114 of query aligns to 3:54/104 of 1x8dA

query
sites
1x8dA
R
 
R
M
 
K
G
 
A
M
 
F
V
 
V
I
 
M
G
 
Q
L
 
V
N
 
N
P
 
P
E
 
D
K
 
A
V
 
H
A
 
E
K
 
E
Y
|
Y
K
 
Q
A
 
R
L
 
R
H
|
H
A
 
N
Q
 
P
V
 
I
W
 
W
P
 
P
E
 
E
I
 
L
L
 
E
A
 
A
L
 
V
I
 
L
S
 
K
E
 
S
C
 
H
N
 
G
I
 
A
A
 
H
N
 
N
Y
|
Y
S
 
A
I
 
I
F
 
Y
L
 
L
K
 
D
E
 
K
P
 
A
E
 
R
N
 
N
L
 
L
L
 
L
F
 
F
G
 
A

Sites not aligning to the query:

P32156 L-rhamnose mutarotase; Rhamnose 1-epimerase; Type-3 mutarotase; EC 5.1.3.32 from Escherichia coli (strain K12) (see paper)
35% identity, 46% coverage: 8:59/114 of query aligns to 3:54/104 of P32156

query
sites
P32156
R
 
R
M
 
K
G
 
A
M
 
F
V
 
V
I
 
M
G
 
Q
L
 
V
N
 
N
P
 
P
E
 
D
K
 
A
V
 
H
A
 
E
K
 
E
Y
|
Y
K
 
Q
A
 
R
L
 
R
H
 
H
A
 
N
Q
 
P
V
 
I
W
 
W
P
 
P
E
 
E
I
 
L
L
 
E
A
 
A
L
 
V
I
 
L
S
 
K
E
 
S
C
 
H
N
 
G
I
 
A
A
 
H
N
 
N
Y
 
Y
S
 
A
I
 
I
F
 
Y
L
 
L
K
 
D
E
 
K
P
 
A
E
 
R
N
 
N
L
 
L
L
 
L
F
 
F
G
 
A

Query Sequence

>WP_008507762.1 NCBI__GCF_000182725.1:WP_008507762.1
MSKHQGQRMGMVIGLNPEKVAKYKALHAQVWPEILALISECNIANYSIFLKEPENLLFGY
WEYVGSDFAADMRKMAESPKNQEWWSVCMPCQKPLETRKEGEWWAMMEEVFHHD

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory