SitesBLAST
Comparing WP_009125666.1 NCBI__GCF_000195635.1:WP_009125666.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2gnaA Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-gal (see paper)
56% identity, 94% coverage: 1:319/340 of query aligns to 3:319/329 of 2gnaA
- binding galactose-uridine-5'-diphosphate: K87 (= K89), S176 (= S178), V177 (= V179), T195 (= T197), M199 (= M201), R201 (= R203), M235 (≠ I237), R254 (= R256), E257 (= E259)
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G13 (= G11), T15 (= T13), G16 (= G14), S17 (= S15), F18 (= F16), S39 (= S38), R40 (= R39), D41 (= D40), K44 (= K43), D63 (= D65), V64 (= V66), A83 (= A85), A84 (= A86), A85 (= A87), K87 (= K89), L125 (= L127), S126 (= S128), Y137 (= Y139), K141 (= K143), Y167 (= Y169), G168 (= G170), V170 (= V172)
2gn9A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glc (see paper)
56% identity, 94% coverage: 1:319/340 of query aligns to 3:319/329 of 2gn9A
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G13 (= G11), T15 (= T13), G16 (= G14), S17 (= S15), F18 (= F16), R40 (= R39), D41 (= D40), K44 (= K43), D63 (= D65), V64 (= V66), A83 (= A85), A84 (= A86), A85 (= A87), K87 (= K89), L125 (= L127), S126 (= S128), K141 (= K143), Y167 (= Y169), G168 (= G170), V170 (= V172), R174 (= R176)
- binding uridine-5'-diphosphate-glucose: K87 (= K89), T127 (= T129), K129 (= K131), Y137 (= Y139), N169 (= N171), S176 (= S178), V177 (= V179), P193 (= P195), T195 (= T197), M199 (= M201), R201 (= R203), M235 (≠ I237), R254 (= R256), E257 (= E259)
2gn6A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glcnac (see paper)
56% identity, 94% coverage: 1:319/340 of query aligns to 3:319/329 of 2gn6A
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G13 (= G11), T15 (= T13), G16 (= G14), S17 (= S15), F18 (= F16), R40 (= R39), D41 (= D40), K44 (= K43), D63 (= D65), V64 (= V66), A84 (= A86), A85 (= A87), K87 (= K89), S126 (= S128), Y137 (= Y139), K141 (= K143), Y167 (= Y169), G168 (= G170), V170 (= V172), S173 (= S175), R174 (= R176)
- binding uridine-diphosphate-n-acetylglucosamine: K87 (= K89), D128 (= D130), K129 (= K131), N169 (= N171), G175 (= G177), S176 (= S178), V177 (= V179), P193 (= P195), I194 (= I196), M199 (= M201), R201 (= R203), M235 (≠ I237), R254 (= R256), E257 (= E259)
2gn4A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADPH and udp-glcnac (see paper)
56% identity, 94% coverage: 1:319/340 of query aligns to 3:319/329 of 2gn4A
- binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate: G13 (= G11), T15 (= T13), G16 (= G14), S17 (= S15), F18 (= F16), S39 (= S38), R40 (= R39), D41 (= D40), K44 (= K43), D63 (= D65), V64 (= V66), A83 (= A85), A84 (= A86), A85 (= A87), K87 (= K89), T102 (= T104), L125 (= L127), S126 (= S128), T127 (= T129), Y137 (= Y139), K141 (= K143), Y167 (= Y169), G168 (= G170), V170 (= V172), S173 (= S175), R174 (= R176)
- binding uridine-diphosphate-n-acetylglucosamine: K87 (= K89), T127 (= T129), D128 (= D130), K129 (= K131), Y137 (= Y139), N169 (= N171), S176 (= S178), V177 (= V179), P193 (= P195), T195 (= T197), M199 (= M201), R201 (= R203), M235 (≠ I237), R254 (= R256), E257 (= E259)
2gn8A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp (see paper)
56% identity, 94% coverage: 1:319/340 of query aligns to 1:317/327 of 2gn8A
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G11 (= G11), T13 (= T13), G14 (= G14), S15 (= S15), F16 (= F16), S37 (= S38), R38 (= R39), D39 (= D40), K42 (= K43), D61 (= D65), V62 (= V66), A81 (= A85), A82 (= A86), A83 (= A87), K85 (= K89), T100 (= T104), L123 (= L127), S124 (= S128), K139 (= K143), Y165 (= Y169), G166 (= G170), V168 (= V172), S171 (= S175), R172 (= R176)
- binding uridine-5'-diphosphate: K127 (= K131), N167 (= N171), V175 (= V179), P191 (= P195), I192 (= I196), T193 (= T197), M197 (= M201), R199 (= R203), M233 (≠ I237), R252 (= R256)
O25511 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
56% identity, 94% coverage: 1:319/340 of query aligns to 7:323/333 of O25511
- TGSF 19:22 (= TGSF 13:16) binding NADP(+)
- SRDELK 43:48 (= SRDELK 38:43) binding NADP(+)
- DV 67:68 (= DV 65:66) binding NADP(+)
- A87 (= A85) binding NADP(+)
- K91 (= K89) binding NADP(+)
- LS 129:130 (= LS 127:128) binding NADP(+)
- K133 (= K131) mutation K->A,E: Loss of activity.
- Y141 (= Y139) binding NADP(+)
- K145 (= K143) binding NADP(+)
- VVGSR 174:178 (≠ VMGSR 172:176) binding NADP(+)
6bwcC X-ray structure of pen from bacillus thuringiensis (see paper)
39% identity, 85% coverage: 4:293/340 of query aligns to 5:299/327 of 6bwcC
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G12 (= G11), T14 (= T13), G15 (= G14), T16 (≠ S15), I17 (≠ F16), S37 (= S38), R38 (= R39), S39 (≠ D40), D63 (= D65), I64 (≠ V66), V83 (≠ A85), A84 (= A86), K87 (= K89), T125 (≠ L127), S127 (≠ T129), Y137 (= Y139), K141 (= K143), F167 (≠ Y169), V170 (= V172), S173 (= S175), R174 (= R176)
- binding uridine-diphosphate-n-acetylglucosamine: K87 (= K89), H88 (≠ Q90), S127 (≠ T129), N128 (≠ D130), Y137 (= Y139), N169 (= N171), S176 (= S178), V177 (= V179), L180 (≠ F182), T192 (≠ P195), T194 (= T197), M198 (= M201), R200 (= R203), L234 (≠ I237), E265 (= E259)
4g5hA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with by-product (see paper)
41% identity, 96% coverage: 2:329/340 of query aligns to 11:333/346 of 4g5hA
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G20 (= G11), T22 (= T13), G23 (= G14), S24 (= S15), F25 (= F16), S45 (= S38), R46 (= R39), D47 (= D40), K50 (= K43), D69 (= D65), V70 (= V66), A89 (= A85), A90 (= A86), A91 (= A87), K93 (= K89), L131 (= L127), T133 (= T129), K147 (= K143), Y173 (= Y169)
- binding [(2R,3R,4R,6R)-3-acetamido-6-methyl-4-oxidanyl-5-oxidanylidene-oxan-2-yl] [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate: Q94 (= Q90), V95 (= V91), K135 (= K131), N175 (= N171), S182 (= S178), V183 (= V179), L186 (≠ F182), T198 (≠ P195), T200 (= T197), M204 (= M201), V240 (≠ I237), R263 (= R256), E266 (= E259), Y278 (≠ A271), S313 (≠ G308), Y314 (≠ F309), E315 (≠ H310), Y316 (= Y311), N320 (= N316)
3w1vA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with inihibitor (see paper)
41% identity, 96% coverage: 2:329/340 of query aligns to 11:333/347 of 3w1vA
- binding [(2R,3S,4R,5R,6R)-5-acetamido-6-[[[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,4-bis(oxidanyl)oxan-2-yl]methylimino-azanylidene-azanium: K93 (= K89), Q94 (= Q90), N175 (= N171), S179 (= S175), R180 (= R176), S182 (= S178), V183 (= V179), L186 (≠ F182), T198 (≠ P195), I199 (= I196), T200 (= T197), M204 (= M201), R206 (= R203), V240 (≠ I237), R263 (= R256), E266 (= E259)
4j2oC Crystal structure of NADP-bound wbjb from a. Baumannii community strain d1279779 (see paper)
40% identity, 97% coverage: 1:331/340 of query aligns to 1:307/316 of 4j2oC
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G11 (= G11), T13 (= T13), G14 (= G14), S15 (= S15), F16 (= F16), S36 (= S38), R37 (= R39), D38 (= D40), K41 (= K43), D60 (= D65), V61 (= V66), A80 (= A85), A81 (= A86), A82 (= A87), K84 (= K89), T99 (= T104), L122 (= L127), K138 (= K143), Y164 (= Y169)
3vvcA Crystal structure of capsular polysaccharide synthesizing enzyme cape , k126e, in apo form (see paper)
40% identity, 96% coverage: 2:329/340 of query aligns to 3:305/318 of 3vvcA
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G12 (= G11), T14 (= T13), G15 (= G14), F17 (= F16), S37 (= S38), R38 (= R39), D39 (= D40), K42 (= K43), D61 (= D65), V62 (= V66), R63 (= R67), A81 (= A85), A82 (= A86), A83 (= A87), K85 (= K89), S124 (= S128), T125 (= T129), K139 (= K143), Y165 (= Y169), G166 (= G170)
4tqgA Crystal structure of megavirus udp-glcnac 4,6-dehydratase, 5-epimerase mg534 (see paper)
36% identity, 88% coverage: 2:299/340 of query aligns to 3:279/297 of 4tqgA
- binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate: G12 (= G11), S14 (≠ T13), G15 (= G14), S16 (= S15), L17 (≠ F16), R36 (= R39), D37 (= D40), D59 (= D65), I60 (≠ V66), A81 (= A85), A82 (= A86), A83 (= A87), K85 (= K89), V128 (≠ L127), Y140 (= Y139), K144 (= K143), Y168 (= Y169), G169 (= G170), V171 (= V172)
3vvbA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in apo form (see paper)
34% identity, 96% coverage: 2:329/340 of query aligns to 1:260/270 of 3vvbA