SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_009140808.1 NCBI__GCF_000225705.1:WP_009140808.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

P69797 PTS system mannose-specific EIIAB component; EIIAB-Man; EIII-Man; EC 2.7.1.191 from Escherichia coli (strain K12) (see 4 papers)
42% identity, 91% coverage: 6:151/160 of query aligns to 164:310/323 of P69797

query
sites
P69797
I
 
I
L
 
G
L
 
L
T
 
A
R
 
R
I
 
I
D
 
D
N
 
D
R
 
R
L
 
L
I
 
I
H
|
H
G
 
G
Q
 
Q
V
 
V
A
 
A
T
 
T
Q
 
R
W
 
W
N
 
T
S
 
K
T
 
E
L
 
T
G
 
N
S
 
V
N
 
S
L
 
R
I
 
I
L
 
I
V
 
V
A
 
V
N
 
S
D
 
D
E
 
E
V
 
V
S
 
A
G
 
A
N
 
D
T
 
T
M
 
V
R
 
R
Q
 
K
N
 
T
L
 
L
M
 
L
K
 
T
M
 
Q
A
 
V
A
 
A
P
 
P
A
 
P
G
 
G
V
 
V
A
 
T
T
 
A
R
x
H
F
 
V
F
 
V
S
 
D
L
 
V
Q
 
A
H
 
K
T
 
M
I
 
I
D
 
R
I
 
V
I
 
Y
A
 
N
K
 
-
A
 
-
S
 
N
P
 
P
K
|
K
-
 
Y
-
 
A
-
 
G
Q
 
E
K
 
R
I
 
V
F
 
M
I
 
L
V
 
L
A
 
F
E
 
T
T
 
N
P
 
P
Q
 
T
D
 
D
V
 
V
L
 
E
T
 
R
L
 
L
V
 
V
K
 
E
G
 
G
G
 
G
V
 
V
P
 
K
I
 
I
R
 
T
K
 
S
V
 
V
N
 
N
I
 
V
G
 
G
N
 
G
M
 
M
H
 
A
M
 
F
S
 
R
E
 
Q
G
 
G
K
 
K
R
 
T
Q
 
Q
V
 
V
A
 
N
T
 
N
S
 
A
V
 
V
A
 
S
V
 
V
D
 
D
D
 
E
A
 
K
D
 
D
V
 
I
A
 
E
A
 
A
F
 
F
K
 
K
E
 
K
L
 
L
Q
 
N
E
 
A
L
 
R
G
 
G
V
 
I
E
 
E
L
 
L
E
 
E
I
 
V
R
 
R
R
 
K
V
 
V
P
 
S
S
 
T
T
 
D
P
 
P

Sites not aligning to the query:

P26380 PTS system fructose-specific EIIB component; EIIB-Fru; Fructose-specific phosphotransferase enzyme IIB component; lev-PTS; p18; EC 2.7.1.202 from Bacillus subtilis (strain 168) (see paper)
37% identity, 94% coverage: 5:155/160 of query aligns to 3:154/163 of P26380

query
sites
P26380
N
 
N
I
 
I
L
 
V
L
 
L
T
 
A
R
 
R
I
 
I
D
 
D
N
 
D
R
 
R
L
 
F
I
 
I
H
|
H
G
 
G
Q
 
Q
V
 
I
A
 
L
T
 
T
Q
 
R
W
 
W
N
 
I
S
 
K
T
 
V
L
 
H
G
 
A
S
 
A
N
 
D
L
 
R
I
 
I
L
 
I
V
 
V
A
 
V
N
 
S
D
 
D
E
 
D
V
 
I
S
 
A
G
 
Q
N
 
D
T
 
E
M
 
M
R
 
R
Q
 
K
N
 
T
L
 
L
M
 
I
K
 
L
M
 
S
A
 
V
A
 
A
P
 
P
A
 
S
G
 
N
V
 
V
A
 
K
T
 
A
R
 
S
F
 
A
F
 
V
S
 
S
L
 
V
Q
 
S
H
 
K
T
 
-
I
 
-
D
 
-
I
 
-
I
 
M
A
 
A
K
 
K
A
 
A
-
 
F
-
 
H
S
 
S
P
 
P
K
 
R
Q
 
Y
K
 
E
-
 
G
-
 
V
-
 
T
I
 
A
F
 
M
I
 
L
V
 
L
A
 
F
E
 
E
T
 
N
P
 
P
Q
 
S
D
 
D
V
 
I
L
 
V
T
 
S
L
 
L
V
 
I
K
 
E
G
 
A
G
 
G
V
 
V
P
 
P
I
 
I
R
 
K
K
 
T
V
 
V
N
 
N
I
 
V
G
 
G
N
 
G
M
 
M
H
 
R
M
 
F
S
 
E
E
 
N
G
 
H
K
 
R
R
 
R
Q
 
Q
V
 
I
A
 
T
T
 
K
S
 
S
V
 
V
A
 
S
V
 
V
D
 
T
D
 
E
A
 
Q
D
 
D
V
 
I
A
 
K
A
 
A
F
 
F
K
 
E
E
 
T
L
 
L
Q
 
S
E
 
D
L
 
K
G
 
G
V
 
V
E
 
K
L
 
L
E
 
E
I
 
L
R
 
R
R
 
Q
V
 
L
P
 
P
S
 
S
T
 
D
P
 
A
V
 
S
E
 
E
D
 
D
I
 
F

Query Sequence

>WP_009140808.1 NCBI__GCF_000225705.1:WP_009140808.1
MAEPNILLTRIDNRLIHGQVATQWNSTLGSNLILVANDEVSGNTMRQNLMKMAAPAGVAT
RFFSLQHTIDIIAKASPKQKIFIVAETPQDVLTLVKGGVPIRKVNIGNMHMSEGKRQVAT
SVAVDDADVAAFKELQELGVELEIRRVPSTPVEDINKLFS

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory