SitesBLAST
Comparing WP_010438069.1 NCBI__GCF_000192475.1:WP_010438069.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
7vw6B Cryo-em structure of formate dehydrogenase 1 from methylorubrum extorquens am1 (see paper)
62% identity, 96% coverage: 19:565/567 of query aligns to 12:556/560 of 7vw6B
- binding fe2/s2 (inorganic) cluster: C108 (= C115), T112 (≠ S119), C113 (= C120), C141 (= C148), L144 (≠ R151), C145 (= C152)
- binding flavin mononucleotide: G221 (= G227), G223 (= G229), K232 (= K238), N248 (= N254), D250 (= D256), Y324 (= Y334), G327 (= G337), E328 (= E338), N363 (≠ H373), N364 (= N374), T367 (= T377)
- binding iron/sulfur cluster: I325 (= I335), P343 (= P353), S496 (= S505), C497 (= C506), G498 (= G507), Q499 (= Q508), C500 (= C509), C503 (= C512), I536 (= I545), C537 (= C546), L539 (= L548), G540 (= G549)
8a6tB Cryo-em structure of the electron bifurcating fe-fe hydrogenase hydabc complex from thermoanaerobacter kivui in the reduced state (see paper)
39% identity, 68% coverage: 183:566/567 of query aligns to 156:554/630 of 8a6tB
- binding flavin mononucleotide: G201 (= G229), N227 (= N254), E230 (= E257), N355 (= N374), G535 (= G547), L536 (= L548)
- binding nadp nicotinamide-adenine-dinucleotide phosphate: S320 (≠ E339), R337 (= R356), R340 (≠ F359), T341 (≠ V360), N342 (≠ A361), S433 (= S451)
- binding iron/sulfur cluster: S487 (= S505), C488 (= C506), G489 (= G507), C491 (= C509), C494 (= C512), C534 (= C546), L536 (= L548), G537 (= G549)
- binding zinc ion: C471 (≠ T489)
Sites not aligning to the query:
- binding fe2/s2 (inorganic) cluster: 31, 33, 36, 82, 85, 86
- binding iron/sulfur cluster: 575, 577, 582, 583, 585, 588, 592, 596, 597, 607, 612, 618, 622, 624, 626, 627
- binding zinc ion: 558, 564
7p8nB Tmhydabc- t. Maritima hydrogenase with bridge closed (see paper)
35% identity, 81% coverage: 110:566/567 of query aligns to 26:540/613 of 7p8nB
- binding fe2/s2 (inorganic) cluster: C31 (= C115), G33 (≠ S117), T34 (≠ L118), C36 (= C120), C67 (= C148), C68 (≠ M149), G69 (= G150), R70 (= R151), C71 (= C152)
- binding flavin mononucleotide: G185 (= G227), R186 (≠ L228), G187 (= G229), N213 (= N254), D215 (= D256), E216 (= E257), G217 (= G258), F301 (≠ Y334), G304 (= G337), E305 (= E338), E306 (= E339), N340 (≠ H373), N341 (= N374), G521 (= G547), L522 (= L548)
- binding iron/sulfur cluster: P320 (= P353), S473 (= S505), C474 (= C506), G475 (= G507), K476 (≠ Q508), C477 (= C509), C480 (= C512), L519 (≠ I545), C520 (= C546), L522 (= L548), G523 (= G549)
- binding zinc ion: C457 (≠ T489)
Sites not aligning to the query:
- binding iron/sulfur cluster: 560, 567, 570, 571, 573, 577, 590, 592, 597, 599, 600, 601, 603, 607
- binding zinc ion: 544, 549, 554
8qh7B Crystal structure of respiratory complex i subunits nuoef from aquifex aeolicus bound to reduced 3-acetylpyridine adenine dinucleotide (without reducing agent) (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 20:411/417 of 8qh7B
- binding acetyl pyridine adenine dinucleotide, reduced: G65 (= G229), G66 (= G230), A67 (= A231), F69 (= F233), K74 (= K238), E93 (= E257), E95 (= E259), Y178 (= Y334), E183 (= E339), Y203 (≠ F359)
- binding 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydro-2h-benzo[g]pteridin-1-id-10(5h)-yl)-5-o-phosphonato-d-ribitol: G63 (= G227), G65 (= G229), K74 (= K238), N90 (= N254), D92 (= D256), E93 (= E257), G181 (= G337), E182 (= E338), V216 (= V372), N217 (≠ H373), N218 (= N374), T221 (= T377)
- binding iron/sulfur cluster: P197 (= P353), T344 (≠ S505), C345 (= C506), G346 (= G507), Q347 (= Q508), C348 (= C509), C351 (= C512), S389 (= S544), I390 (= I545), C391 (= C546), L393 (= L548), G394 (= G549)
8qg1B Crystal structure of oxidized respiratory complex i subunits nuoef from aquifex aeolicus bound to adp-ribose (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 20:411/417 of 8qg1B
- binding adenosine-5-diphosphoribose: G66 (= G230), A67 (= A231), F69 (= F233), K74 (= K238), E183 (= E339), Y203 (≠ F359)
- binding flavin mononucleotide: G63 (= G227), G65 (= G229), K74 (= K238), N90 (= N254), D92 (= D256), E93 (= E257), Y178 (= Y334), G181 (= G337), E182 (= E338), V216 (= V372), N217 (≠ H373), N218 (= N374), T221 (= T377)
- binding iron/sulfur cluster: P197 (= P353), T344 (≠ S505), C345 (= C506), G346 (= G507), Q347 (= Q508), C348 (= C509), C351 (= C512), I390 (= I545), C391 (= C546), L393 (= L548), G394 (= G549)
8qgwB Crystal structure of oxidized respiratory complex i subunits nuoef from aquifex aeolicus bound to oxidized 3-acetylpyridine adenine dinucleotide (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 20:411/418 of 8qgwB
- binding 3-acetylpyridine adenine dinucleotide: G66 (= G230), A67 (= A231), F69 (= F233), K74 (= K238), E183 (= E339), Y203 (≠ F359)
- binding flavin mononucleotide: G63 (= G227), G65 (= G229), K74 (= K238), N90 (= N254), E93 (= E257), Y178 (= Y334), G181 (= G337), E182 (= E338), E183 (= E339), V216 (= V372), N217 (≠ H373), N218 (= N374), T221 (= T377)
- binding iron/sulfur cluster: P197 (= P353), T344 (≠ S505), C345 (= C506), G346 (= G507), Q347 (= Q508), C348 (= C509), C351 (= C512), I390 (= I545), C391 (= C546), L393 (= L548), G394 (= G549)
6q9cB Crystal structure of aquifex aeolicus nadh-quinone oxidoreductase subunits nuoe and nuof bound to nadh under anaerobic conditions (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 21:412/418 of 6q9cB
- binding flavin mononucleotide: G64 (= G227), G66 (= G229), K75 (= K238), N91 (= N254), D93 (= D256), E94 (= E257), G182 (= G337), E183 (= E338), E184 (= E339), V217 (= V372), N218 (≠ H373), N219 (= N374), T222 (= T377), G393 (= G547)
- binding 1,4-dihydronicotinamide adenine dinucleotide: G66 (= G229), G67 (= G230), A68 (= A231), F70 (= F233), K75 (= K238), E94 (= E257), E96 (= E259), Y179 (= Y334), E184 (= E339), Y204 (≠ F359)
- binding iron/sulfur cluster: P198 (= P353), T345 (≠ S505), C346 (= C506), G347 (= G507), Q348 (= Q508), C349 (= C509), C352 (= C512), I391 (= I545), C392 (= C546), L394 (= L548), G395 (= G549)
6hl3B Wild-type nuoef from aquifex aeolicus - oxidized form bound to NAD+ (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 20:411/416 of 6hl3B
- binding flavin mononucleotide: G63 (= G227), G65 (= G229), K74 (= K238), N90 (= N254), D92 (= D256), E93 (= E257), G181 (= G337), E182 (= E338), E183 (= E339), V216 (= V372), N217 (≠ H373), N218 (= N374), T221 (= T377)
- binding nicotinamide-adenine-dinucleotide: G65 (= G229), G66 (= G230), A67 (= A231), F69 (= F233), K74 (= K238), E95 (= E259), Y178 (= Y334), E183 (= E339), K200 (≠ R356), Y203 (≠ F359)
- binding iron/sulfur cluster: I179 (= I335), P197 (= P353), T344 (≠ S505), C345 (= C506), G346 (= G507), Q347 (= Q508), C348 (= C509), C351 (= C512), S389 (= S544), I390 (= I545), C391 (= C546), L393 (= L548), G394 (= G549)
6hl2B Wild-type nuoef from aquifex aeolicus - oxidized form (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 20:411/416 of 6hl2B
- binding flavin mononucleotide: G63 (= G227), G65 (= G229), K74 (= K238), N90 (= N254), E93 (= E257), G181 (= G337), E182 (= E338), E183 (= E339), V216 (= V372), N217 (≠ H373), N218 (= N374), T221 (= T377)
- binding iron/sulfur cluster: P197 (= P353), T344 (≠ S505), C345 (= C506), G346 (= G507), Q347 (= Q508), C348 (= C509), C351 (= C512), S389 (= S544), I390 (= I545), C391 (= C546), G394 (= G549)
6saqB Wild-type nuoef from aquifex aeolicus bound to nadh-oh (see paper)
41% identity, 68% coverage: 183:566/567 of query aligns to 21:412/419 of 6saqB