Comparing WP_010876205.1 NCBI__GCF_000008645.1:WP_010876205.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2gptA Crystal structure of arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase in complex with tartrate and shikimate (see paper)
34% identity, 90% coverage: 5:204/221 of query aligns to 7:215/498 of 2gptA
Sites not aligning to the query:
2o7qA Crystal structure of the a. Thaliana dhq-dehydroshikimate-sdh- shikimate-NADP(h)
34% identity, 90% coverage: 5:204/221 of query aligns to 7:215/501 of 2o7qA
Sites not aligning to the query:
6bmqA Crystal structure of arabidopsis dehydroquinate dehydratase-shikimate dehydrogenase (t381g mutant) in complex with tartrate and shikimate (see paper)
34% identity, 90% coverage: 5:204/221 of query aligns to 7:215/498 of 6bmqA
Sites not aligning to the query:
2o7sA Crystal structure of the a. Thaliana dhq-dehydroshikimate-sdh- shikimate-NADP(h)
34% identity, 90% coverage: 5:204/221 of query aligns to 7:215/500 of 2o7sA
Sites not aligning to the query:
Q9SQT8 Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic; DHQ-SDH protein; DHQase-SORase; Protein EMBRYO DEFECTIVE 3004; EC 4.2.1.10; EC 1.1.1.25 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
34% identity, 90% coverage: 5:204/221 of query aligns to 96:304/603 of Q9SQT8
Sites not aligning to the query:
1sfjA 2.4a crystal structure of staphylococcus aureus type i 3- dehydroquinase, with 3-dehydroquinate bound (see paper)
34% identity, 91% coverage: 7:207/221 of query aligns to 2:217/227 of 1sfjA
Q186A6 3-dehydroquinate dehydratase; 3-dehydroquinase; Type I DHQase; Type I dehydroquinase; DHQ1; EC 4.2.1.10 from Clostridioides difficile (strain 630) (Peptoclostridium difficile) (see paper)
33% identity, 91% coverage: 4:205/221 of query aligns to 18:238/255 of Q186A6
4h3dB 1.95 angstrom crystal structure of of type i 3-dehydroquinate dehydratase (arod) from clostridium difficile with covalent modified comenic acid.
33% identity, 91% coverage: 4:205/221 of query aligns to 18:238/254 of 4h3dB
3js3A Crystal structure of type i 3-dehydroquinate dehydratase (arod) from clostridium difficile with covalent reaction intermediate (see paper)
33% identity, 91% coverage: 4:205/221 of query aligns to 18:238/253 of 3js3A
Q6GII7 3-dehydroquinate dehydratase; 3-dehydroquinase; Type I DHQase; Type I dehydroquinase; DHQ1; EC 4.2.1.10 from Staphylococcus aureus (strain MRSA252) (see paper)
33% identity, 86% coverage: 19:207/221 of query aligns to 22:228/238 of Q6GII7
O66440 3-dehydroquinate dehydratase; 3-dehydroquinase; Type I DHQase; Type I dehydroquinase; DHQ1; EC 4.2.1.10 from Aquifex aeolicus (strain VF5) (see paper)
33% identity, 86% coverage: 18:208/221 of query aligns to 13:207/219 of O66440
P58687 3-dehydroquinate dehydratase; 3-dehydroquinase; DHQD; Type I DHQase; Type I dehydroquinase; DHQ1; EC 4.2.1.10 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
33% identity, 92% coverage: 4:207/221 of query aligns to 17:239/252 of P58687
4gujA 1.50 angstrom crystal structure of the salmonella enterica 3- dehydroquinate dehydratase (arod) in complex with shikimate (see paper)
33% identity, 92% coverage: 4:207/221 of query aligns to 16:238/251 of 4gujA
4guiA 1.78 angstrom crystal structure of the salmonella enterica 3- dehydroquinate dehydratase (arod) in complex with quinate (see paper)
33% identity, 92% coverage: 4:207/221 of query aligns to 16:238/251 of 4guiA
3m7wA Crystal structure of type i 3-dehydroquinate dehydratase (arod) from salmonella typhimurium lt2 in covalent complex with dehydroquinate (see paper)
33% identity, 92% coverage: 4:207/221 of query aligns to 16:238/251 of 3m7wA
8b2aBBB 3-dehydroquinate dehydratase (see paper)
33% identity, 86% coverage: 19:207/221 of query aligns to 22:228/238 of 8b2aBBB
6sfhA Crystal structure of dhq1 from staphylococcus aureus covalently modified by ligand 7 (see paper)
33% identity, 86% coverage: 19:207/221 of query aligns to 21:227/237 of 6sfhA
4guhB 1.95 angstrom crystal structure of the salmonella enterica 3- dehydroquinate dehydratase (arod) e86a mutant in complex with dehydroshikimate (crystal form #2) (see paper)
32% identity, 92% coverage: 4:207/221 of query aligns to 30:252/265 of 4guhB
4clmB Structure of salmonella typhi type i dehydroquinase irreversibly inhibited with a 1,3,4-trihydroxyciclohexane-1-carboxylic acid derivative (see paper)
30% identity, 95% coverage: 4:214/221 of query aligns to 16:245/251 of 4clmB
8b2cAAA 3-dehydroquinate dehydratase (see paper)
30% identity, 95% coverage: 4:214/221 of query aligns to 17:246/252 of 8b2cAAA
>WP_010876205.1 NCBI__GCF_000008645.1:WP_010876205.1
MNTKICVPVFEKTAPEVTESAGRAIDAGADILEIRIDGLQNPGEVNIRELIEDIGFPVIA
TNRSPVEGGHFSGSEDERIKLLMAAAEVADFVDIELSSAREDIERVTGSARRSIVSYHNF
RETPSLEALLRIVRMAKEMGDIAKVAVMPENLADTLVVLQLLTFEEDTVAISMGELGKYT
RVAAALFGSPITFASMGRGTAPGQMDVDVTRKMIGELMPED
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory