SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_010876439.1 NCBI__GCF_000008645.1:WP_010876439.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

2gtvX Nmr structure of monomeric chorismate mutase from methanococcus jannaschii (see paper)
41% identity, 90% coverage: 8:95/98 of query aligns to 3:98/104 of 2gtvX

query
sites
2gtvX

E

E

V

K

L

L

R

A

R

E

S

I

R
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R

Q

K

K

K

I

I

D

D

G

E

I

I

D

D

R

N

D

K

I

I

L

L

D

K

-

A

-

R

-

W

-

P

-

W

-

A

-

E

-

K

L

L

I

I

T

A

S

E

R
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R

I

N

A

S

L

L

A

A

R

K

E

D

I
x
V

A

A

E

E

A

I

K
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K

E

N

V

Q

L

L

G

G

M

I

E

P

I

I

L

N

D
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D

P

P

E

E

R
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R

E
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E

L

K

Q

Y

I

I

I

Y

E

D

R

R

T

I

R

R

K

K

I

L

A

C

R

K

E

E

N

H

G

N

I

V

D

D

E

E

N

N

K

I

L

G

T

I

E

K

L

I

M

F

K

Q

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R

L

L

M

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D

E

L

H

S
x
N

K

K

T

A

E

L

Q
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Q

K

K

E

Q

M

Y

L

L

binding 8-hydroxy-2-oxa-bicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid: R9 (= R14), R34 (= R31), V41 (≠ I38), K45 (= K42), D54 (= D51), R57 (= R54), E58 (= E55), N90 (≠ S87), Q94 (= Q91)

Query Sequence

>WP_010876439.1 NCBI__GCF_000008645.1:WP_010876439.1
MDEYRAREVLRRSRQKIDGIDRDILDLITSRIALAREIAEAKEVLGMEILDPERELQIIE
RTRKIARENGIDENKLTELMKILMDLSKTEQKEMLRRQ

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory