Comparing WP_010964030.1 NCBI__GCF_000008765.1:WP_010964030.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P27876 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Bacillus subtilis (strain 168) (see paper)
60% identity, 99% coverage: 1:246/248 of query aligns to 1:247/253 of P27876
P00943 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
55% identity, 99% coverage: 1:246/248 of query aligns to 1:247/253 of P00943
3uwuA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-3-phosphate (see paper)
54% identity, 99% coverage: 1:246/248 of query aligns to 1:249/253 of 3uwuA
Q6GIL6 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Staphylococcus aureus (strain MRSA252) (see paper)
54% identity, 99% coverage: 1:246/248 of query aligns to 1:249/253 of Q6GIL6
3uwzA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-2-phosphate (see paper)
54% identity, 99% coverage: 1:246/248 of query aligns to 2:250/254 of 3uwzA
3uwwA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 3-phosphoglyceric acid (see paper)
54% identity, 99% coverage: 1:246/248 of query aligns to 2:250/254 of 3uwwA
1btmA Triosephosphate isomerase (tim) complexed with 2-phosphoglycolic acid (see paper)
55% identity, 99% coverage: 2:246/248 of query aligns to 1:246/251 of 1btmA
3uwvA Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid (see paper)
54% identity, 99% coverage: 1:246/248 of query aligns to 3:251/255 of 3uwvA
3uwzB Crystal structure of staphylococcus aureus triosephosphate isomerase complexed with glycerol-2-phosphate (see paper)
53% identity, 99% coverage: 1:246/248 of query aligns to 1:246/250 of 3uwzB
P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
52% identity, 96% coverage: 2:238/248 of query aligns to 402:639/654 of P36204
Sites not aligning to the query:
6bveA Triosephosphate isomerase of synechocystis in complex with 2- phosphoglycolic acid (see paper)
48% identity, 100% coverage: 1:248/248 of query aligns to 1:240/242 of 6bveA
4y96A Crystal structure of triosephosphate isomerase from gemmata obscuriglobus (see paper)
44% identity, 99% coverage: 2:247/248 of query aligns to 2:247/250 of 4y96A
6neeB Crystal structure of a reconstructed ancestor of triosephosphate isomerase from eukaryotes (see paper)
50% identity, 99% coverage: 2:247/248 of query aligns to 4:249/252 of 6neeB
5zfxB Crystal structure of triosephosphate isomerase from opisthorchis viverrini (see paper)
46% identity, 99% coverage: 2:247/248 of query aligns to 1:245/248 of 5zfxB
3taoA Structure of mycobacterium tuberculosis triosephosphate isomerase bound to phosphoglycolohydroxamate (see paper)
42% identity, 98% coverage: 2:245/248 of query aligns to 2:250/256 of 3taoA
P9WG43 Triosephosphate isomerase; TIM; TPI; Triose-phosphate isomerase; EC 5.3.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
42% identity, 98% coverage: 2:245/248 of query aligns to 3:251/261 of P9WG43
2y63A Crystal structure of leishmanial e65q-tim complexed with bromohydroxyacetone phosphate (see paper)
45% identity, 98% coverage: 4:247/248 of query aligns to 5:246/249 of 2y63A
2y61A Crystal structure of leishmanial e65q-tim complexed with s-glycidol phosphate (see paper)
45% identity, 98% coverage: 4:247/248 of query aligns to 5:246/249 of 2y61A
2vxnA E65q-tim complexed with phosphoglycolohydroxamate at 0.82 a resolution (see paper)
45% identity, 98% coverage: 4:247/248 of query aligns to 5:246/249 of 2vxnA
1if2A X-ray structure of leishmania mexicana triosephosphate isomerase complexed with ipp (see paper)
45% identity, 98% coverage: 4:247/248 of query aligns to 5:246/249 of 1if2A
>WP_010964030.1 NCBI__GCF_000008765.1:WP_010964030.1
MRTPIIAGNWKMNNTISESLKLIEELKPLVKDAKAEVVVAPTAVSLETVVNATKGSNIKV
AAQNAHFEESGAFTGEISLKALEELGVSYVILGHSERRQYFNETDCALNKKVKAAFAHNI
TPILCCGETLEEREANVTNEVTGKQIKLDLAGLSAEQAAKVVIAYEPIWAIGTGKTATDE
QANETIGAIRKTVEVMFGKEVAEKVRIQYGGSVKPNTIKAQMAKPEIDGALVGGASLKAA
DFAAIVNF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory