Comparing WP_011318570.1 NCBI__GCF_000204075.1:WP_011318570.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
38% identity, 97% coverage: 6:360/367 of query aligns to 8:356/364 of P97084
1lc7A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
37% identity, 97% coverage: 6:360/367 of query aligns to 5:353/358 of 1lc7A
1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate (see paper)
37% identity, 97% coverage: 6:360/367 of query aligns to 2:350/356 of 1lc8A
1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica (see paper)
37% identity, 97% coverage: 6:360/367 of query aligns to 1:349/355 of 1lkcA
8bj3A Crystal structure of medicago truncatula histidinol-phosphate aminotransferase (hisn6) in complex with histidinol-phosphate (see paper)
32% identity, 92% coverage: 13:349/367 of query aligns to 24:350/360 of 8bj3A
Sites not aligning to the query:
2f8jA Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
25% identity, 69% coverage: 80:334/367 of query aligns to 83:313/335 of 2f8jA
1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
25% identity, 77% coverage: 53:334/367 of query aligns to 48:307/329 of 1uu1A
Sites not aligning to the query:
1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
25% identity, 77% coverage: 53:334/367 of query aligns to 47:306/328 of 1uu0A
1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (see paper)
25% identity, 77% coverage: 53:334/367 of query aligns to 48:307/329 of 1h1cA
Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
25% identity, 69% coverage: 80:334/367 of query aligns to 82:312/335 of Q9X0D0
P0DV65 L-serine phosphate decarboxylase; CobD homolog SMUL_1544; SmCobD; L-serine O-phosphate decarboxylase; L-Ser-P decarboxylase; Norcobamide biosynthesis protein SMUL_1544; Threonine phosphate decarboxylase-like enzyme; EC 4.1.1.- from Sulfurospirillum multivorans (strain DM 12446 / JCM 15788 / NBRC 109480) (see paper)
23% identity, 86% coverage: 51:364/367 of query aligns to 76:391/392 of P0DV65
Sites not aligning to the query:
1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate (see paper)
30% identity, 64% coverage: 124:358/367 of query aligns to 108:350/354 of 1fg7A
Sites not aligning to the query:
1fg3A Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
30% identity, 64% coverage: 124:358/367 of query aligns to 108:350/354 of 1fg3A
Sites not aligning to the query:
1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate (see paper)
30% identity, 64% coverage: 124:357/367 of query aligns to 94:335/335 of 1geyA
Sites not aligning to the query:
7szpA Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
25% identity, 86% coverage: 43:357/367 of query aligns to 42:349/353 of 7szpA
4wbtA Crystal structure of histidinol-phosphate aminotransferase from sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
27% identity, 82% coverage: 27:327/367 of query aligns to 36:333/369 of 4wbtA
4r5zA Crystal structure of rv3772 encoded aminotransferase (see paper)
25% identity, 89% coverage: 25:349/367 of query aligns to 25:352/353 of 4r5zA
4r2nA Crystal structure of rv3772 in complex with its substrate (see paper)
25% identity, 89% coverage: 25:349/367 of query aligns to 25:352/353 of 4r2nA
Sites not aligning to the query:
4r8dA Crystal structure of rv1600 encoded aminotransferase in complex with plp-mes from mycobacterium tuberculosis
26% identity, 84% coverage: 41:349/367 of query aligns to 50:364/369 of 4r8dA
3ly1D Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
25% identity, 75% coverage: 13:287/367 of query aligns to 7:280/354 of 3ly1D
>WP_011318570.1 NCBI__GCF_000204075.1:WP_011318570.1
MRQPDHGGNLAWAAALAGCPADAIVDFSASISPLGPPQSAIAAIQSQISNLRHYPDPDYS
ELRLALGHFHQLPLEWILPGNGSAELLTLAGRELAQLAATVLITPAFGDYYRTLRAYHAR
VLEFPLVSVESRVLGTECHLTQLHTQHSGLSTNYALLLNNPHNPTGKLFTREAILPLLEQ
FALVVVDEAFMDFVPPDEEQSLIPVVAEYPNLVILRSLTKFYSLPGLRLGYAIAHPDRLQ
KWQLWRDPWPVNTLAAAAAIAALEDREFQVQTWQWLPPAREELFQGLTAIPGLTPQASAA
NFLLVETQQSSLELQQKLLQQHQILIRDCLSFKELGDRFFRLAVRSHTDNQRLTKALKTI
AQNSLDH
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory