Comparing WP_011382532.1 NCBI__GCF_000009985.1:WP_011382532.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P74285 UTP--glucose-1-phosphate uridylyltransferase; Cyanobacterial UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase; UDP-Glc PPase; EC 2.7.7.9 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
30% identity, 62% coverage: 123:340/349 of query aligns to 4:241/388 of P74285
7d73E Cryo-em structure of gmppa/gmppb complex bound to gtp (state i) (see paper)
31% identity, 65% coverage: 123:349/349 of query aligns to 4:237/360 of 7d73E
7d72K Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
31% identity, 65% coverage: 123:349/349 of query aligns to 4:237/360 of 7d72K
7d72E Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
31% identity, 65% coverage: 123:349/349 of query aligns to 4:237/360 of 7d72E
7whsA Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gtp (see paper)
31% identity, 62% coverage: 123:337/349 of query aligns to 4:225/366 of 7whsA
7x8kA Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound) (see paper)
32% identity, 62% coverage: 123:337/349 of query aligns to 4:225/365 of 7x8kA
O22287 Mannose-1-phosphate guanylyltransferase 1; GDP-mannose pyrophosphorylase 1; Protein CYTOKINESIS DEFECTIVE 1; Protein EMBRYO DEFECTIVE 101; Protein HYPERSENSITIVE TO AMMONIUM ION 1; Protein SENSITIVE TO OZONE 1; Protein VITAMIN C DEFECTIVE 1; EC 2.7.7.13 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
32% identity, 62% coverage: 123:337/349 of query aligns to 4:226/361 of O22287
Sites not aligning to the query:
7x8kB Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound) (see paper)
32% identity, 62% coverage: 123:337/349 of query aligns to 4:226/367 of 7x8kB
7whtA Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gdp-mannose (see paper)
31% identity, 62% coverage: 123:337/349 of query aligns to 4:218/360 of 7whtA
Q88QT2 N-acetylmuramate alpha-1-phosphate uridylyltransferase; MurNAc-1P uridylyltransferase; MurNAc-alpha-1P uridylyltransferase; EC 2.7.7.99 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
31% identity, 63% coverage: 122:341/349 of query aligns to 3:216/223 of Q88QT2
4y7uA Structural analysis of muru (see paper)
31% identity, 63% coverage: 122:341/349 of query aligns to 3:216/224 of 4y7uA
4y7vA Structural analysis of muru (see paper)
31% identity, 63% coverage: 122:341/349 of query aligns to 3:211/216 of 4y7vA
6t37A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 5:231/289 of 6t37A
Sites not aligning to the query:
5ifyA Crystal structure of glucose-1-phosphate thymidylyltransferase from burkholderia vietnamiensis in complex with 2 -deoxyuridine-5'- monophosphate and 2'-deoxy-thymidine-b-l-rhamnose
29% identity, 62% coverage: 123:340/349 of query aligns to 5:234/293 of 5ifyA
Sites not aligning to the query:
4b5bA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 6:235/293 of 4b5bA
Sites not aligning to the query:
4b4gA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 6:235/293 of 4b4gA
Sites not aligning to the query:
4b42A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 6:235/293 of 4b42A
Sites not aligning to the query:
4b3uA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 12:241/299 of 4b3uA
Sites not aligning to the query:
4asyA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 6:235/293 of 4asyA
Sites not aligning to the query:
4b4mA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
28% identity, 62% coverage: 123:340/349 of query aligns to 9:238/296 of 4b4mA
Sites not aligning to the query:
>WP_011382532.1 NCBI__GCF_000009985.1:WP_011382532.1
MKRWQDTLVSPTTPVLDAIKALDLGAMQIVLVVDGQSRLLGTITDGDIRRGLLRGLPLES
PASEVMNPRFHHGRVEDEAGVLLATMRRLQISQMPLLDGDGRVVGLKTLEQMLALDGCDN
WVVLMAGGEGRRLRPLTQDVPKPLLPVGPRPILETILKNFIEAGFRNFFISVNYRAEQVE
SHFGDGSALGVSIRYLREDRQLGTAGALGLLPGTPSEPLIVMNGDILTTVDFKQLLAFHQ
EHRAAATMAVREYHFEVPYGVVEVEGTRLKGIEEKPVVRNFVNAGIYVLNPEVLNLVKPG
QPHNMPQIYQTLMDGGQDCAVFPIREYWLDIGRLDDFDRANLDFHEVFR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory