SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_011385002.1 NCBI__GCF_000009985.1:WP_011385002.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 2 papers)
28% identity, 56% coverage: 62:212/268 of query aligns to 86:234/296 of P68183

query
sites
P68183

W

W

L

N

S

S

L

V

K

K

I

V

A

A

F

G

L

I

N

S

A

A

C

I

L

G

A

I

T

V

A

A

L

L

G

S

T

T

M

T

A

C

A

A

V

Y

V

A

L

F

V

A

R

R

F

M

R

R

R

-

F

F

S

P

G

G

R

K

A

A

-

T

L

L

F

L

T

K

G

G

M

M

V

L

S

I

A

F

P

Q

L

M

V

-

M

F

P

P

E

A

I

V

I

L

T

S

G

L

L

V

A

A

L

L

L

Y

L

A

L

L

F

F

V

D

G

R

M

L

E

G

N

E

L

Y

L

I

G

P

W

F

P

I

D

G

G

L

R

N

S

T

M

H

T

G

T

G

I

V

V

I

I

F

A

A

H

Y

V

L

T

G

F

-

S

G

L

I

S

A

F

L

V

H

T

V

V

W

V

T

V

I

R

K

S

G

R

Y

L

F

A

E

Q

T

M

I

D

D

L

S

S

S

L

L

E

E

E
|
E

A

A

A
|
A

M

A

D

L

L

D

G
|
G

A

A

R

T

P

P

L

W

T

Q

V

A

F

F

F

R

S

L

I

V

T

L

L

L

P
|
P

I

L

I

S

A

V

P

P

A

I

L

L

A

A

A

V

G

V

W

F

L

I

L

L

A

S

F

F

T

I

L

A

S

A

V

I

D

T

D

E

V

V

V

P

I

V

S

A

A

S

E190 (= E168) mutation E->A,C,K,L: Reduction of transport rate.
A192 (= A170) mutation A->D,S,L: Loss of transport and MalK dissociation from the membrane.
G196 (= G174) mutation to A: No effect.; mutation to P: Loss of transport and MalK dissociation from the membrane.
P209 (= P187) mutation to A: No effect.

Query Sequence

>WP_011385002.1 NCBI__GCF_000009985.1:WP_011385002.1
MKNRGFALYTALALVYAFLYLPIALLVIYSFNASKLVTVWGGFSTKWYGELLHDAQVLDA
AWLSLKIAFLNACLATALGTMAAVVLVRFRRFSGRALFTGMVSAPLVMPEIITGLALLLL
FVGMENLLGWPDGRSMTTIVIAHVTFSLSFVTVVVRSRLAQMDLSLEEAAMDLGARPLTV
FFSITLPIIAPALAAGWLLAFTLSVDDVVISAFVSGPGATPLPIVIFSKVRLGVSPEINA
LATIVVALVGVAIAVAGRVMMTREKQGG

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory