Comparing WP_011385204.1 NCBI__GCF_000009985.1:WP_011385204.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
45% identity, 84% coverage: 53:339/340 of query aligns to 14:301/303 of 8skyB
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
45% identity, 84% coverage: 53:339/340 of query aligns to 15:302/303 of 8sutA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
47% identity, 67% coverage: 110:338/340 of query aligns to 55:274/277 of 6iymA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
41% identity, 63% coverage: 118:332/340 of query aligns to 66:269/279 of 6v77B
3r6oA Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
35% identity, 78% coverage: 72:335/340 of query aligns to 4:257/265 of 3r6oA
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
38% identity, 62% coverage: 127:338/340 of query aligns to 73:278/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
38% identity, 62% coverage: 127:338/340 of query aligns to 73:278/290 of 8gsrA
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
39% identity, 66% coverage: 111:336/340 of query aligns to 50:264/269 of 4dbhA
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
32% identity, 70% coverage: 98:336/340 of query aligns to 42:274/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
32% identity, 70% coverage: 98:336/340 of query aligns to 42:274/280 of 6j5xA
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
39% identity, 66% coverage: 111:336/340 of query aligns to 50:245/252 of 3qdfA
1gttA Crystal structure of hpce (see paper)
33% identity, 74% coverage: 59:309/340 of query aligns to 137:392/421 of 1gttA
Q6P587 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; YisK-like protein; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 3 papers)
37% identity, 60% coverage: 115:317/340 of query aligns to 8:205/224 of Q6P587
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
37% identity, 60% coverage: 115:317/340 of query aligns to 3:200/218 of 6fogA
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
37% identity, 57% coverage: 125:317/340 of query aligns to 12:199/216 of 6sbiA
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
33% identity, 80% coverage: 39:309/340 of query aligns to 1:238/264 of 6jvwB
6j5yA Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
36% identity, 56% coverage: 123:313/340 of query aligns to 22:212/233 of 6j5yA
3v77A Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from oleispira antarctica (see paper)
33% identity, 56% coverage: 119:309/340 of query aligns to 10:197/224 of 3v77A
1nkqA Crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein
29% identity, 61% coverage: 124:330/340 of query aligns to 8:224/247 of 1nkqA
2hzyA Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate (see paper)
28% identity, 37% coverage: 182:307/340 of query aligns to 196:353/416 of 2hzyA
Sites not aligning to the query:
>WP_011385204.1 NCBI__GCF_000009985.1:WP_011385204.1
MDEKRRQFLTLGAGVAAGALLTRAAGAAGPIPNSAAGALRLVTYSAGGVAPRVGVVKASG
RVVDLGAAAKARGMALAFDPASMVSLIRAGDFALAQARQLMQEGPETGPLVSEVRLLAPI
PEPSRNVYAVGWNYLEHFKEGEAMRLKSADLPEHPVFFTKAVGTVNGPYDPIPYDAAVST
SIDWECELAVIIGKGGKNIAEADAMKHVFGFCVINDTTARDVQQKKHGGQWFKGKSLDGH
GPLGPWIVPASDIDHTRVHLITRVNGVVKQDASTEQMYFKVPRIIAELSAGLTLEPGDII
ATGTPPGVGGARKPPEFLKPGDVMETEIVEIGLLRNVIGG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory