SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_011385764.1 NCBI__GCF_000009985.1:WP_011385764.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 2 papers)
26% identity, 86% coverage: 29:226/230 of query aligns to 102:291/296 of P68183

query
sites
P68183

L

L

G

S

L

T

G

T

C

C

A

A

W

Y

V

A

L

F

A

A

R

R

L

M

D

R

F

F

P

P

G

G

K

K

V

A

V

T

V

L

D

L

G

K

I

G

I

M

H

L

L

I

P

F

L

Q

V

M

L

F

P

P

P

A

V

V

V

L

V

S

G

L

Y

V

G

A

L

L

L

Y

V

A

V

L

L

F

G

D

R

R

R

L

G

G

V

E

V

-

G

-

G

-

W

-

L

-

Y

Y

D

I

W

P

F

F

G

-

I

-

T

-

L

I

A

G

F

L

N

N

W

T

K

H

G

G

A

G

A

V

V

I

A

F

S

A

A

Y

V

L

I

G

A

G

F

I

P

A

L

L

M

H

V

V

R

W

A

T

I

I

R

K

L

G

A

Y

L

F

E

E

G

T

V

I

D

D

R

S

G

S

L

L

E

E

Q
x
E

A

A

A
|
A

R

A

T

L

L

D

G
|
G

C

A

G

T

P

P

I

W

R

Q

T

A

F

F

W

R

S

L

V

V

T

L

L

L

P
|
P

L

L

M

S

L

V

P

P

G

I

V

L

L

A

T

V

G

V

V

F

I

I

L

L

A

S

F

F

A

I

R

A

S

A

L

I

S

T

E

E

F

V

G

P

A

V

T

A

I

S

T

L

F

L

V

L

S

R

N

D

I

V

P

N

G

S

E

Y

T

T

R

L

T

A

L

V

P

G

I

M

A

Q

L

Q

Y

Y

A

L

L

N

T

P

Q

Q

-

N

-

Y

V

L

P

W

G

G

G

D

D

F

E

A

A

A

A

A

L

A

R

V

L

M

C

S

V

A

I

L

S

P

V

I

V

T

V

I

A

V

F

F

A

-

A

-

L

L

L

L

A

A

S

Q

E

R

Y

W

L

L

A

V

R

N

R

G

V

L

Q

T

A

A

E190 (≠ Q125) mutation E->A,C,K,L: Reduction of transport rate.
A192 (= A127) mutation A->D,S,L: Loss of transport and MalK dissociation from the membrane.
G196 (= G131) mutation to A: No effect.; mutation to P: Loss of transport and MalK dissociation from the membrane.
P209 (= P144) mutation to A: No effect.

Query Sequence

>WP_011385764.1 NCBI__GCF_000009985.1:WP_011385764.1
MFTLTPLEMEALRLSLLVSFWAVAASLPLGLGCAWVLARLDFPGKVVVDGIIHLPLVLPP
VVVGYGLLVVLGRRGVVGGWLYDWFGITLAFNWKGAAVASAVIAFPLMVRAIRLALEGVD
RGLEQAARTLGCGPIRTFWSVTLPLMLPGVLTGVILAFARSLSEFGATITFVSNIPGETR
TLPIALYALTQVPGGDEAALRLCVISVVVAFAALLASEYLARRVQARLKG

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory