SitesBLAST
Comparing WP_011386481.1 NCBI__GCF_000009985.1:WP_011386481.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
7qh2C Cryo-em structure of ldh-etfab complex from acetobacterium woodii (see paper)
27% identity, 50% coverage: 45:516/936 of query aligns to 45:460/467 of 7qh2C
- binding flavin-adenine dinucleotide: V73 (≠ F73), G75 (≠ A75), S76 (≠ A76), G77 (= G77), T78 (= T78), G79 (≠ S79), L80 (= L80), A83 (≠ Q83), C84 (≠ A84), P137 (= P135), G138 (≠ A136), E139 (≠ S137), A142 (≠ C141), T143 (≠ K142), G146 (= G145), N147 (≠ I146), S149 (≠ A148), T150 (≠ N149), A152 (= A151), G153 (≠ S152), E203 (= E253), G204 (= G254), I209 (= I259), E422 (= E478), H423 (= H479)
- binding fe (iii) ion: H377 (= H433), H384 (= H440), E422 (= E478)
Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial; EC 1.1.99.39 from Homo sapiens (Human) (see 7 papers)
25% identity, 52% coverage: 28:516/936 of query aligns to 53:513/521 of Q8N465
- S109 (≠ E54) to W: in D2HGA1; uncertain significance; significant loss of catalytic activity; dbSNP:rs142050154
- N127 (≠ T72) to K: in D2HGA1; uncertain significance; complete loss of catalytic activity; dbSNP:rs762857195
- G131 (≠ A76) to V: in D2HGA1; uncertain significance; complete loss of catalytic activity
- I147 (= I92) to S: in D2HGA1; uncertain significance; severe phenotype; almost complete loss of catalytic activity; dbSNP:rs121434361
- M153 (≠ T98) to T: in D2HGA1; uncertain significance; significant loss of catalytic activity; to V: in D2HGA1; uncertain significance; significant loss of catalytic activity; dbSNP:rs1432270139
- C172 (≠ V115) to Y: in D2HGA1; uncertain significance; moderate reduction in catalytic activity; dbSNP:rs773735172
- P189 (≠ G132) to L: in D2HGA1; uncertain significance; almost complete loss of catalytic activity; dbSNP:rs587783517
- A205 (= A148) to V: in D2HGA1; uncertain significance; almost complete loss of catalytic activity; dbSNP:rs750889931
- A231 (= A174) to V: in D2HGA1; uncertain significance; significant loss of catalytic activity
- G233 (= G176) to S: in D2HGA1; uncertain significance; no effect on catalytic activity; dbSNP:rs374535734
- D375 (= D369) to Y: in D2HGA1; uncertain significance; moderate reduction in catalytic activity; dbSNP:rs267606759
- R386 (= R380) binding ; binding ; binding ; mutation to A: Loss of catalytic activity.
- T390 (≠ F384) binding ; binding ; mutation to A: Significantly reduced catalytic activity.
- V399 (= V390) to M: in D2HGA1; uncertain significance; moderate reduction in catalytic activity; dbSNP:rs746519212
- K401 (= K392) binding ; binding ; mutation to A: Loss of catalytic activity.
- R419 (≠ E417) to H: in D2HGA1; uncertain significance; moderate reduction in catalytic activity; dbSNP:rs199908032
- A426 (≠ G424) to T: in D2HGA1; uncertain significance; no effect on catalytic activity; dbSNP:rs146578303
- H434 (= H433) binding ; mutation to A: Loss of catalytic activity.
- G436 (≠ L435) to V: slight reduction in catalytic activity
- N439 (= N438) to D: in D2HGA1; uncertain significance; mild phenotype; moderate reduction in catalytic activity; dbSNP:rs121434362
- H441 (= H440) binding ; mutation to A: Loss of catalytic activity.
- N443 (≠ T442) binding ; mutation to A: Significantly reduced catalytic activity.
- V444 (≠ F443) to A: in D2HGA1; uncertain significance; severe phenotype; significant reduction in catalytic activity; dbSNP:rs121434360
- A446 (≠ Q445) to V: in D2HGA1; uncertain significance; moderate reduction in catalytic activity; dbSNP:rs746956176
- E475 (= E478) binding ; mutation to A: Loss of catalytic activity.
- H476 (= H479) binding ; binding ; binding ; mutation to A: Loss of catalytic activity.
- G477 (= G480) to R: in D2HGA1; uncertain significance; almost complete loss of catalytic activity; dbSNP:rs1453924640
Sites not aligning to the query:
- 15 R → G: in dbSNP:rs4675887
- 169:521 natural variant: Missing (in D2HGA1; uncertain significance)
- 400:521 natural variant: Missing (in D2HGA1; uncertain significance; complete loss of catalytic activity)
6lpnB Crystal structure of human d-2-hydroxyglutarate dehydrogenase in apo form (see paper)
25% identity, 52% coverage: 28:516/936 of query aligns to 1:461/467 of 6lpnB
- binding flavin-adenine dinucleotide: W40 (vs. gap), P76 (≠ F73), G78 (≠ A75), G79 (≠ A76), N80 (≠ G77), T81 (= T78), G82 (≠ S79), M83 (≠ L80), G86 (≠ Q83), S87 (≠ A84), L140 (≠ P135), A142 (≠ S137), C146 (= C141), H147 (≠ K142), G150 (= G145), N151 (≠ I146), A153 (= A148), T154 (≠ N149), G208 (= G254), I212 (≠ F258), I213 (= I259), E423 (= E478), N460 (= N515)
6lpxA Crystal structure of human d-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-og) (see paper)
25% identity, 50% coverage: 46:516/936 of query aligns to 48:460/466 of 6lpxA
- binding 2-oxoglutaric acid: R333 (= R380), T337 (≠ F384), K348 (= K392), Y379 (≠ F431), H381 (= H433), H388 (= H440), H423 (= H479)
- binding flavin-adenine dinucleotide: P75 (≠ F73), Q76 (≠ R74), G77 (≠ A75), G78 (≠ A76), N79 (≠ G77), T80 (= T78), G81 (≠ S79), M82 (≠ L80), G85 (≠ Q83), S86 (≠ A84), L139 (≠ P135), G140 (≠ A136), A141 (≠ S137), C145 (= C141), G149 (= G145), N150 (≠ I146), A152 (= A148), T153 (≠ N149), G157 (= G153), G207 (= G254), I212 (= I259), E422 (= E478), N459 (= N515)
- binding zinc ion: H381 (= H433), H388 (= H440), E422 (= E478)
Sites not aligning to the query:
6lpuA Crystal structure of human d-2-hydroxyglutarate dehydrogenase in complex with l-2-hydroxyglutarate (l-2-hg) (see paper)
25% identity, 50% coverage: 46:516/936 of query aligns to 48:460/466 of 6lpuA
- binding flavin-adenine dinucleotide: P75 (≠ F73), G77 (≠ A75), G78 (≠ A76), N79 (≠ G77), T80 (= T78), G81 (≠ S79), G85 (≠ Q83), S86 (≠ A84), L139 (≠ P135), G140 (≠ A136), A141 (≠ S137), C145 (= C141), H146 (≠ K142), G148 (= G144), G149 (= G145), N150 (≠ I146), A152 (= A148), T153 (≠ N149), A155 (= A151), E206 (= E253), G207 (= G254), I211 (≠ F258), I212 (= I259), E422 (= E478), N459 (= N515)
- binding (2s)-2-hydroxypentanedioic acid: R333 (= R380), T337 (≠ F384), K348 (= K392), Y379 (≠ F431), H381 (= H433), H388 (= H440), H423 (= H479)
- binding zinc ion: H381 (= H433), H388 (= H440), E422 (= E478)
Sites not aligning to the query:
6lpqA Crystal structure of human d-2-hydroxyglutarate dehydrogenase in complex with d-malate (d-mal) (see paper)
25% identity, 50% coverage: 46:516/936 of query aligns to 48:460/466 of 6lpqA
- binding flavin-adenine dinucleotide: P75 (≠ F73), G77 (≠ A75), G78 (≠ A76), N79 (≠ G77), T80 (= T78), G81 (≠ S79), G85 (≠ Q83), S86 (≠ A84), L139 (≠ P135), G140 (≠ A136), A141 (≠ S137), C145 (= C141), H146 (≠ K142), G149 (= G145), N150 (≠ I146), A152 (= A148), T153 (≠ N149), A155 (= A151), G157 (= G153), E206 (= E253), G207 (= G254), I211 (≠ F258), I212 (= I259), E422 (= E478), N459 (= N515)
- binding d-malate: M82 (≠ L80), R333 (= R380), T337 (≠ F384), K348 (= K392), Y379 (≠ F431), H381 (= H433), H388 (= H440), E422 (= E478), H423 (= H479)
- binding zinc ion: H381 (= H433), H388 (= H440), E422 (= E478)
Sites not aligning to the query:
6lppA Crystal structure of human d-2-hydroxyglutarate dehydrogenase in complex with d-2-hydroxyglutarate (d-2-hg) (see paper)
25% identity, 50% coverage: 46:516/936 of query aligns to 48:460/466 of 6lppA
- binding (2R)-2-hydroxypentanedioic acid: R333 (= R380), T337 (≠ F384), K348 (= K392), Y379 (≠ F431), H381 (= H433), H388 (= H440), N390 (≠ T442), H423 (= H479)
- binding flavin-adenine dinucleotide: P75 (≠ F73), G77 (≠ A75), G78 (≠ A76), N79 (≠ G77), T80 (= T78), G81 (≠ S79), M82 (≠ L80), G85 (≠ Q83), S86 (≠ A84), L139 (≠ P135), G140 (≠ A136), A141 (≠ S137), C145 (= C141), G149 (= G145), N150 (≠ I146), A152 (= A148), T153 (≠ N149), A155 (= A151), G157 (= G153), G207 (= G254), I212 (= I259), E422 (= E478), H423 (= H479)
- binding zinc ion: H381 (= H433), H388 (= H440), E422 (= E478)
Sites not aligning to the query:
8jduA Crystal structure of mldhd in complex with 2-ketovaleric acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:455/455 of 8jduA
- binding 2-oxopentanoic acid: R318 (= R380), W322 (≠ F384), H369 (= H433), H376 (= H440), H414 (= H479)
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W322 (≠ F384), E413 (= E478), N450 (= N515)
- binding manganese (ii) ion: H369 (= H433), H376 (= H440), E413 (= E478)
8jdeA Crystal structure of mldhd in complex with d-lactate (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:455/455 of 8jdeA
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W322 (≠ F384), E413 (= E478), H414 (= H479), N450 (= N515)
- binding lactic acid: R318 (= R380), H369 (= H433), H376 (= H440), H414 (= H479)
- binding manganese (ii) ion: H369 (= H433), H376 (= H440), E413 (= E478)
8jdxA Crystal structure of mldhd in complex with 2-ketoisovaleric acid (see paper)
25% identity, 54% coverage: 11:520/936 of query aligns to 5:455/455 of 8jdxA
- binding flavin-adenine dinucleotide: E32 (≠ A38), P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W322 (≠ F384), E413 (= E478), H414 (= H479), N450 (= N515)
- binding 3-methyl-2-oxobutanoic acid: R318 (= R380), H369 (= H433), H376 (= H440), H414 (= H479)
- binding manganese (ii) ion: H369 (= H433), H376 (= H440), E413 (= E478)
8jdsA Crystal structure of mldhd in complex with pyruvate (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:456/456 of 8jdsA
- binding flavin-adenine dinucleotide: E32 (≠ A38), P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W323 (≠ F384), E414 (= E478), H415 (= H479), N451 (= N515)
- binding manganese (ii) ion: H370 (= H433), H377 (= H440), E414 (= E478)
- binding pyruvic acid: R319 (= R380), H370 (= H433), H377 (= H440), H415 (= H479)
8jdtA Crystal structure of mldhd in complex with 2-ketobutanoic acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:455/455 of 8jdtA
- binding 2-ketobutyric acid: R318 (= R380), H369 (= H433), H376 (= H440), H414 (= H479)
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W322 (≠ F384), E413 (= E478), H414 (= H479), N450 (= N515)
- binding manganese (ii) ion: H369 (= H433), H376 (= H440), E413 (= E478)
P9WIT1 Uncharacterized FAD-linked oxidoreductase Rv2280; EC 1.-.-.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
26% identity, 50% coverage: 56:520/936 of query aligns to 51:456/459 of P9WIT1
- K354 (≠ A411) modified: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
8jdvA Crystal structure of mldhd in complex with 2-ketohexanoic acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:454/454 of 8jdvA
- binding 2-Ketohexanoic acid: V75 (≠ S79), R317 (= R380), W321 (≠ F384), H368 (= H433), H375 (= H440), H413 (= H479)
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (≠ G94), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W321 (≠ F384), Y322 (≠ P385), E412 (= E478), H413 (= H479), N449 (= N515)
- binding manganese (ii) ion: H368 (= H433), H375 (= H440), E412 (= E478)
8jdzA Crystal structure of mldhd in complex with 2-keto-3-methylvaleric acid (see paper)
25% identity, 54% coverage: 11:520/936 of query aligns to 5:454/454 of 8jdzA
- binding (3S)-3-methyl-2-oxopentanoic acid: R318 (= R380), W322 (≠ F384), H369 (= H433), H376 (= H440), H413 (= H479)
- binding flavin-adenine dinucleotide: E32 (≠ A38), P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), W322 (≠ F384), E412 (= E478), H413 (= H479), N449 (= N515)
- binding manganese (ii) ion: H369 (= H433), H376 (= H440), E412 (= E478)
8jdyA Crystal structure of mldhd in complex with 2-ketoisocaproic acid (see paper)
25% identity, 54% coverage: 11:520/936 of query aligns to 5:454/454 of 8jdyA
- binding 2-oxo-4-methylpentanoic acid: R318 (= R380), W322 (≠ F384), S336 (≠ I399), H369 (= H433), H376 (= H440), H413 (= H479)
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), E412 (= E478), N449 (= N515)
- binding manganese (ii) ion: H369 (= H433), H376 (= H440), E412 (= E478)
8jdrA Crystal structure of h405a mldhd in complex with d-2-hydroxy-3-methyl- valeric acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:456/456 of 8jdrA
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), Y324 (≠ P385), H370 (= H433), E414 (= E478), N451 (= N515)
- binding (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid: R319 (= R380), W323 (≠ F384), H415 (= H479)
8jdqA Crystal structure of h405a mldhd in complex with d-2-hydroxyisocaproic acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:456/456 of 8jdqA
- binding (2R)-2-hydroxy-4-methylpentanoic acid: R319 (= R380), W323 (≠ F384), H370 (= H433), H415 (= H479)
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), H370 (= H433), E414 (= E478), N451 (= N515)
8jdoA Crystal structure of h405a mldhd in complex with d-2-hydroxyhexanoic acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:456/456 of 8jdoA
- binding (2R)-2-hydroxyhexanoic acid: R319 (= R380), W323 (≠ F384), H415 (= H479)
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), Y324 (≠ P385), H370 (= H433), E414 (= E478), N451 (= N515)
8jdnA Crystal structure of h405a mldhd in complex with d-2-hydroxyvaleric acid (see paper)
24% identity, 54% coverage: 11:520/936 of query aligns to 5:456/456 of 8jdnA
- binding flavin-adenine dinucleotide: P68 (vs. gap), G70 (≠ R74), T71 (≠ A75), G72 (≠ A76), T73 (≠ G77), G74 (≠ T78), G78 (= G82), V79 (≠ Q83), L90 (= L93), P132 (= P135), G133 (≠ A136), A134 (≠ S137), G140 (= G145), M141 (≠ I146), A143 (= A148), T144 (≠ N149), A146 (= A151), S147 (= S152), E200 (= E253), G201 (= G254), I206 (= I259), H370 (= H433), E414 (= E478), N451 (= N515)
- binding (2R)-2-oxidanylpentanoic acid: R319 (= R380), W323 (≠ F384), H415 (= H479)
Query Sequence
>WP_011386481.1 NCBI__GCF_000009985.1:WP_011386481.1
MTRTAPDYSALLQDLTGVMPVSRLITDPLRRLAYGTDASFYRLVPQVVAEVRDEAEVKGV
LAACRRHGAPVTFRAAGTSLSGQAVSDSVLMILGTGWTQAVVEDEGKRIRLQPGVIGAEA
NRRLAAFARKIGPDPASIDSCKIGGIAANNASGMCCGTSDNSYQTVMSMRLVLADGTLVD
TGNPESVAAFRASHAELLSRLDDMGRRVRDDETLAGRIRHKFAIKNTTGYSLNALVDFTD
PLDILTHLMIGSEGTLGFIAEITYRTVPEHAHKASALLLFPDIAEACRAVVALKQAPVSA
VELMDRASLRCVEDKPGMPAQIRGLADGVTSLLVEARGETAEALAANLAEIGRVLSGVTT
LFPPAFTDDPYEYGTLWKIRKGLFPALGAVRKVGTTVIIEDVAFPIESLAAATTDLEHLC
RKHGYDEAIIFGHALDGNLHFTFTQDFGIKEEVDRYARFMDEVAELVVNKYDGSLKAEHG
TGRNMAPFVEMEWGTEATALMWDIKGLLDPLGLLNPGVLLDKDPRAHLNNLKPLPAADSL
VDTCIECGFCERMCPSHGLTLSPRQRITSWREISRRTAANENSDELRRLYDYQGIDTCAA
CGLCATACPVGIETGRLTKSLRGRRLGSGAHAVGQWASRHYGAAMAATRFGLGAAALVSR
LAGPSAMAAMASGLRTLSGGRTPKLGEHLPTAADFAPPANAPSGERVVYFPTCAARTMGP
ASGDPEKDSLPTVMTRVLARAGFGVVIPDGVENLCCGQAFESKGLQATADAKAAELEAAL
FKASDHGRLPIVMDASACAWRMKTYLGERLKVVDSVEFLHDAALPRLSPTPQDAPVLVHV
NCGARKQGLDDKMVGLAKACAKTAIVPEAVGCCGFAGDKGFTNPELNDHALRHLAPQVPQ
GCEAGYSSNRTCEIGLADHADVPYRSIVYLLDRTTR
Or try a new SitesBLAST search
SitesBLAST's Database
SitesBLAST's database includes
(1) SwissProt
entries with experimentally-supported functional features;
and (2) protein structures with bound ligands, from the
BioLip database.
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory