Comparing WP_011427914.1 NCBI__GCF_000092045.1:WP_011427914.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2buuA Crystal structure of protocatechuate 3,4-dioxygenase from acinetobacter sp. Adp1 mutant r457s in complex with 4-nitrocatechol
53% identity, 97% coverage: 7:203/203 of query aligns to 2:202/202 of 2buuA
2buqA Crystal structure of wild-type protocatechuate 3,4-dioxygenase from acinetobacter sp. Adp1 in complex with catechol (see paper)
53% identity, 97% coverage: 7:203/203 of query aligns to 2:202/202 of 2buqA
4whsC 4-fluorocatechol bound to protocatechuate 3,4-dioxygenase (pseudomonas putida) at ph 8.5 (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 4whsC
4whrA Anhydride reaction intermediate trapped in protocatechuate 3,4- dioxygenase (pseudomonas putida) at ph 8.5 (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 4whrA
4whqA Alkylperoxo reaction intermediate trapped in protocatechuate 3,4- dioxygenase (pseudomonas putida) at ph 6.5 (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 4whqA
4whoA Resting protocatechuate 3,4-dioxygenase (pseudomonas putida) at ph 8.5 (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 4whoA
3pcmF Structure of protocatechuate 3,4-dioxygenase complexed with 6- hydroxynicotinic acid n-oxide and cyanide (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pcmF
3pclA Structure of protocatechuate 3,4-dioxygenase complexed with 2- hydroxyisonicotinic acid n-oxide and cyanide (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pclA
3pciA Structure of protocatechuate 3,4-dioxygenase complexed with 3-iodo-4- hydroxybenzoate (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pciA
3pchA Structure of protocatechuate 3,4-dioxygenase complexed with 3-chloro- 4-hydroxybenzoate (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pchA
3pcgC Structure of protocatechuate 3,4-dioxygenase complexed with the inhibitor 4-hydroxyphenylacetate (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pcgC
3pcfA Structure of protocatechuate 3,4-dioxygenase complexed with 3-fluro-4- hydroxybenzoate (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pcfA
3pceC Structure of protocatechuate 3,4-dioxygenase complexed with 3- hydroxyphenylacetate (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pceC
3pcbF Structure of protocatechuate 3,4-dioxygenase complexed with 3- hydroxybenzoate (see paper)
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3pcbF
3mi5A Axial ligand swapping in double mutant maintains intradiol-cleavage chemistry in protocatechuate 3,4-dioxygenase
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3mi5A
3mflA Axial ligand swapping in double mutant maintains intradiol-cleavage chemistry in protocatechuate 3,4-dioxygenase
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3mflA
3lxvB Tyrosine 447 of protocatechuate 3,4-dioxygenase controls efficient progress through catalysis
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3lxvB
3lxvA Tyrosine 447 of protocatechuate 3,4-dioxygenase controls efficient progress through catalysis
45% identity, 97% coverage: 7:203/203 of query aligns to 5:200/200 of 3lxvA
P00437 Protocatechuate 3,4-dioxygenase beta chain; 3,4-PCD; EC 1.13.11.3 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
35% identity, 98% coverage: 2:200/203 of query aligns to 35:236/239 of P00437
Sites not aligning to the query:
4whrB Anhydride reaction intermediate trapped in protocatechuate 3,4- dioxygenase (pseudomonas putida) at ph 8.5 (see paper)
35% identity, 98% coverage: 2:200/203 of query aligns to 34:235/238 of 4whrB
Sites not aligning to the query:
>WP_011427914.1 NCBI__GCF_000092045.1:WP_011427914.1
MQQLGYLKETPSQTAGPYVHIGLTPNFCDITGVYDSDLGTQMVNDKTLGERITVTGRIFD
GAGALVRDAVAEIWQADSAGLYNSPSELRGAADPNFAGWGRCPTRAEDGVYSFETIKPGR
VPFKDGRRQAPHITVWIVARGINIGLHTRMYFPEETEANASDPLLSRIEHRERVATMIAT
RDGATCHFDIHLQGPHETVFLDI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory