Comparing WP_011427992.1 NCBI__GCF_000092045.1:WP_011427992.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
Q01468 2-hydroxymuconate tautomerase; 4-oxalocrotonate tautomerase; 4-OT; EC 5.3.2.6 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
42% identity, 98% coverage: 1:60/61 of query aligns to 1:60/63 of Q01468
6bgnA Crystal structure of 4-oxalocrotonate tautomerase after incubation with 5-fluoro-2-hydroxy-2,4-pentadienoate (see paper)
41% identity, 97% coverage: 2:60/61 of query aligns to 1:59/59 of 6bgnA
5tigA Crystal structure of 4-oxalocrotonate tautomerase inactivated by brhpd (see paper)
41% identity, 97% coverage: 2:60/61 of query aligns to 1:59/62 of 5tigA
Sites not aligning to the query:
1bjpA Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2- oxo-3-pentynoate at 2.4 angstroms resolution (see paper)
41% identity, 97% coverage: 2:60/61 of query aligns to 1:59/62 of 1bjpA
Sites not aligning to the query:
P70994 2-hydroxymuconate tautomerase; (2Z,4E)-2-hydroxyhexa-2,4-dienedioate keto-enol isomerase; 4-oxalocrotonate tautomerase; 4-OT; EC 5.3.2.6 from Bacillus subtilis (strain 168) (see paper)
43% identity, 92% coverage: 1:56/61 of query aligns to 1:56/62 of P70994
6ghwC Substituting the prolines of 4-oxalocrotonate tautomerase with non- canonical analogue (2s)-3,4-dehydroproline (see paper)
41% identity, 92% coverage: 2:57/61 of query aligns to 1:56/57 of 6ghwC
2opaA Ywhb binary complex with 2-fluoro-p-hydroxycinnamate
42% identity, 90% coverage: 2:56/61 of query aligns to 1:55/61 of 2opaA
Sites not aligning to the query:
5cloM Crystal structure of a 4-oxalocrotonate tautomerase mutant in complex with nitrostyrene at 2.3 angstrom (see paper)
41% identity, 92% coverage: 2:57/61 of query aligns to 1:56/57 of 5cloM
>WP_011427992.1 NCBI__GCF_000092045.1:WP_011427992.1
MPILHLQMHPGRTDEQKRAFVREATRAAVDTLACPPESVEILITEVAKDSWAVGGKLKSE
G
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Lawrence Berkeley National Laboratory