Comparing WP_011446055.1 NCBI__GCF_000013325.1:WP_011446055.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2hwgA Structure of phosphorylated enzyme i of the phosphoenolpyruvate:sugar phosphotransferase system (see paper)
36% identity, 66% coverage: 282:833/836 of query aligns to 1:569/572 of 2hwgA
P08839 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Escherichia coli (strain K12) (see 2 papers)
36% identity, 66% coverage: 282:833/836 of query aligns to 2:570/575 of P08839
P23533 Phosphoenolpyruvate-protein phosphotransferase; Phosphotransferase system, enzyme I; EC 2.7.3.9 from Staphylococcus carnosus (strain TM300) (see paper)
36% identity, 59% coverage: 340:834/836 of query aligns to 70:572/573 of P23533
2wqdA Crystal structure of enzyme i of the phosphoenolpyruvate:sugar phosphotransferase system in the dephosphorylated state (see paper)
35% identity, 66% coverage: 282:832/836 of query aligns to 4:570/570 of 2wqdA
2xz7A Crystal structure of the phosphoenolpyruvate-binding domain of enzyme i in complex with phosphoenolpyruvate from the thermoanaerobacter tengcongensis pep-sugar phosphotransferase system (pts) (see paper)
42% identity, 36% coverage: 533:835/836 of query aligns to 17:324/324 of 2xz7A
2xz9A Crystal structure from the phosphoenolpyruvate-binding domain of enzyme i in complex with pyruvate from the thermoanaerobacter tengcongensis pep-sugar phosphotransferase system (pts) (see paper)
42% identity, 36% coverage: 533:835/836 of query aligns to 10:317/317 of 2xz9A
5lu4A C4-type pyruvate phosphate dikinase: conformational intermediate of central domain in the swiveling mechanism (see paper)
30% identity, 44% coverage: 426:791/836 of query aligns to 426:839/850 of 5lu4A
Sites not aligning to the query:
P37349 PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM; Dihydroxyacetone kinase subunit M; EC 2.7.1.121 from Escherichia coli (strain K12) (see paper)
31% identity, 39% coverage: 167:489/836 of query aligns to 154:462/472 of P37349
Sites not aligning to the query:
5jvjB C4-type pyruvate phosphate dikinase: different conformational states of the nucleotide binding domain in the dimer (see paper)
28% identity, 44% coverage: 426:791/836 of query aligns to 353:784/797 of 5jvjB
Sites not aligning to the query:
Q39735 Pyruvate, phosphate dikinase, chloroplastic; Cold-sensitive pyruvate, orthophosphate dikinase; Pyruvate, orthophosphate dikinase; EC 2.7.9.1 from Flaveria bidentis (Coastal plain yellowtops) (Ethulia bidentis) (see 2 papers)
28% identity, 44% coverage: 426:791/836 of query aligns to 505:940/953 of Q39735
Sites not aligning to the query:
5jvlA C4-type pyruvate phospate dikinase: nucleotide binding domain with bound atp analogue (see paper)
28% identity, 44% coverage: 426:791/836 of query aligns to 426:861/874 of 5jvlA
Sites not aligning to the query:
P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see paper)
44% identity, 15% coverage: 7:132/836 of query aligns to 501:626/648 of P09323
Sites not aligning to the query:
1vbgA Pyruvate phosphate dikinase from maize (see paper)
30% identity, 36% coverage: 426:730/836 of query aligns to 426:784/874 of 1vbgA
Sites not aligning to the query:
P69783 PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component from Escherichia coli (strain K12) (see 6 papers)
41% identity, 15% coverage: 3:129/836 of query aligns to 19:145/169 of P69783
Sites not aligning to the query:
P11155 Pyruvate, phosphate dikinase 1, chloroplastic; Pyruvate, orthophosphate dikinase 1; EC 2.7.9.1 from Zea mays (Maize) (see 7 papers)
30% identity, 36% coverage: 426:730/836 of query aligns to 499:857/947 of P11155
Sites not aligning to the query:
1glcF Cation promoted association (cpa) of a regulatory and target protein is controlled by phosphorylation (see paper)
40% identity, 15% coverage: 1:129/836 of query aligns to 9:137/161 of 1glcF
1o2fA Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
40% identity, 15% coverage: 4:129/836 of query aligns to 1:126/150 of 1o2fA
5jvlB C4-type pyruvate phospate dikinase: nucleotide binding domain with bound atp analogue (see paper)
30% identity, 31% coverage: 536:791/836 of query aligns to 180:507/520 of 5jvlB
Sites not aligning to the query:
1kc7A Pyruvate phosphate dikinase with bound mg-phosphonopyruvate (see paper)
27% identity, 44% coverage: 426:791/836 of query aligns to 424:857/872 of 1kc7A
Sites not aligning to the query:
P22983 Pyruvate, phosphate dikinase; Pyruvate, orthophosphate dikinase; EC 2.7.9.1 from Clostridium symbiosum (Bacteroides symbiosus) (see 4 papers)
27% identity, 44% coverage: 426:791/836 of query aligns to 425:858/874 of P22983
Sites not aligning to the query:
>WP_011446055.1 NCBI__GCF_000013325.1:WP_011446055.1
MMGSIVLSAPIAGWVSALDEVPDGVFSARLLGDGVAIDPVEGLLCAPCDGEILSVHAARH
AVTMAGEGGVELLMHLGIDTVELKGDGFETLVRAGHRVVRGQPLLRFSLDDLAGRAPSLV
SPVIVTNGDRFTISSCTVDALVAVGDDLIRLDPVGVAPSPDRAPVGEAVGAIVVVPLPNG
LHARPAARLGEAARAFAAETRIVKNGRAVSTRSPVGLLGLSIQLGDEILVEASGPDASQA
VAALVDLIRSGLGEGAEHDAAAEPRASSAGMPPFAPVPDGALRGNLASPGFALGTCHRLD
RSEPELPVQGKGKEEERIRLLSAMDHLRSRLAISSEVSPKAAICSAHRALLDDPELEAAA
LSRIAEGEDAAHAWREACRASAVVLRGSGSARFAERADDVLDLGRQLVTILIGELDETLA
FPPGTILLADELLPSQIMQLGAEVTGIALANGGPTSHVAILAASMGIPMLVAIGDALAGV
RAGDKAILDADGGFLLPAPGAAALAEAEAEVAARQARRADALASASELCHSRDGARIEVF
ANLGSLDDARRAVSAGAEGCGLLRTEFLFLERESAPTVAQQAELYAGIADALGGRPLIVR
LLDIGGDKPATYLPIAPEANPALGLRGIRVGLAHPDVLEDQLRAILSVERGGALRIMVPM
VTGVAEVREVRQRVDRISAELGLAQRVEVGIMVETPAAAATAFLLAPHADFMSIGTNDLT
QYVLAMDRDNPAVAGGIDGLHPAVLNLIAQTVRGAQSVGRWTGVCGGLAADRLAVPLLLG
LGVTELSVPLRQLPEIKALVRGLSISDCKTLALEALQLESAAEIRALSRAFVETLP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory