Comparing WP_011605773.1 NCBI__GCF_000058485.1:WP_011605773.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 13 hits to proteins with known functional sites (download)
7lgpB Dape enzyme from shigella flexneri
27% identity, 86% coverage: 21:358/394 of query aligns to 7:361/377 of 7lgpB
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
22% identity, 89% coverage: 18:369/394 of query aligns to 6:379/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
22% identity, 89% coverage: 18:369/394 of query aligns to 2:375/377 of P44514
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
28% identity, 89% coverage: 18:369/394 of query aligns to 2:375/375 of 4pqaA
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
28% identity, 89% coverage: 18:369/394 of query aligns to 2:375/376 of 4o23A
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
28% identity, 79% coverage: 49:358/394 of query aligns to 38:346/360 of 2f7vA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
27% identity, 61% coverage: 32:272/394 of query aligns to 16:267/377 of 7t1qA
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
28% identity, 79% coverage: 49:358/394 of query aligns to 37:351/366 of Q8P8J5
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
24% identity, 86% coverage: 16:353/394 of query aligns to 5:362/383 of 7uoiA
5xoyA Crystal structure of lysk from thermus thermophilus in complex with lysine (see paper)
27% identity, 86% coverage: 20:358/394 of query aligns to 2:323/341 of 5xoyA
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
25% identity, 68% coverage: 72:340/394 of query aligns to 88:389/426 of 3pfoA
Sites not aligning to the query:
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
23% identity, 85% coverage: 21:354/394 of query aligns to 6:360/381 of 8uw6B
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
34% identity, 31% coverage: 21:144/394 of query aligns to 5:135/265 of 4op4B
Sites not aligning to the query:
>WP_011605773.1 NCBI__GCF_000058485.1:WP_011605773.1
MYSQSGRYPTAGVEVLERTDLLRLAAALVEVPSVSGDEHLLAGLVEHRLRARAPGLRMIR
DGNNIIATTRGAQAGKPARDRHVVLAGHLDTVPAAKNYPTAIPGTVSGLGAVDMKGGLAV
MLVLAERAQDSDHHLTFVFYDNEEVGSRRSGMTLLFDRYQDFLQADLAILLEPTGGLLEA
GCQGNLVVELRYDGSRAHTARPWRGVNAIHRATPALARFGSFEPGPAVVDGLTYRQSLSV
VGVSSGVQGNVVPDACQVRVNFRHAPNLSSEEALGTVVGLAGDADGTQVVLSSPPAPPNL
EHPLLAALRASAGVDVRPKLGWTDVGRFAAHGVPAVNFGPGDSELAHTGRETVSGAELAA
CHAALARFLFADAAGIPPDRLRNIGPHPASEVRP
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory