Comparing WP_011607175.1 NCBI__GCF_000058485.1:WP_011607175.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3tdtA Complex of tetrahydrodipicolinate n-succinyltransferase with 2-amino- 6-oxopimelate and coenzyme a (see paper)
41% identity, 95% coverage: 10:274/280 of query aligns to 2:271/274 of 3tdtA
2tdtA Complex of tetrahydrodipicolinate n-succinyltransferase with 2- aminopimelate and coenzyme a (see paper)
41% identity, 95% coverage: 10:274/280 of query aligns to 2:271/274 of 2tdtA
1kgtA Crystal structure of tetrahydrodipicolinate n-succinyltransferase in complex with pimelate and succinyl-coa (see paper)
41% identity, 95% coverage: 10:274/280 of query aligns to 2:271/274 of 1kgtA
1kgqA Crystal structure of tetrahydrodipicolinate n-succinyltransferase in complex with l-2-aminopimelate and succinamide-coa (see paper)
41% identity, 95% coverage: 10:274/280 of query aligns to 2:271/274 of 1kgqA
3r8yA Structure of the bacillus anthracis tetrahydropicolinate succinyltransferase
43% identity, 32% coverage: 103:192/280 of query aligns to 77:167/203 of 3r8yA
P43889 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
32% identity, 34% coverage: 114:208/280 of query aligns to 330:428/456 of P43889
Sites not aligning to the query:
4kqlA Hin glmu bound to wg578 (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 4kqlA
Sites not aligning to the query:
4kpzA Hin glmu bound to a small molecule fragment (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 4kpzA
Sites not aligning to the query:
4kpxA Hin glmu bound to wg766 (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 4kpxA
Sites not aligning to the query:
4knxA Hin glmu bound to wg176 (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 4knxA
Sites not aligning to the query:
4knrA Hin glmu bound to wg188 (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 4knrA
Sites not aligning to the query:
4e1kA Glmu in complex with a quinazoline compound (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 4e1kA
Sites not aligning to the query:
2w0wA Crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 2
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 2w0wA
Sites not aligning to the query:
2w0vA Crystal structure of glmu from haemophilus influenzae in complex with quinazoline inhibitor 1
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 2w0vA
Sites not aligning to the query:
2vd4A Structure of small-molecule inhibitor of glmu from haemophilus influenzae reveals an allosteric binding site (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 2vd4A
Sites not aligning to the query:
2v0lA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu) (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 2v0lA
Sites not aligning to the query:
2v0kA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu) (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 2v0kA
Sites not aligning to the query:
2v0iA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu) (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/450 of 2v0iA
Sites not aligning to the query:
2v0jA Characterization of substrate binding and catalysis of the potential antibacterial target n-acetylglucosamine-1-phosphate uridyltransferase (glmu) (see paper)
32% identity, 34% coverage: 114:208/280 of query aligns to 327:425/449 of 2v0jA
Sites not aligning to the query:
4ac3A S.Pneumoniae glmu in complex with an antibacterial inhibitor (see paper)
29% identity, 50% coverage: 100:238/280 of query aligns to 318:438/456 of 4ac3A
Sites not aligning to the query:
>WP_011607175.1 NCBI__GCF_000058485.1:WP_011607175.1
MSAPKTSIDSPIDPIIDELWDRRADLTPDDADARKTIVAAVDAIDAGIARVATVAADGSV
VVDERAKRAILLSFKVLPMAESAAGDFQYHDRMPLKTRFDGVRVVPGAIVRWGAHVQPGA
ILMPSYTNIGGYVGAGTLVDTWATVGSCAQVGSNVHLSGGVGLGGVLEPPNAVPVVIEDD
AFVGSRCMVVDGARVRRGAKLGAGAILTASTHVFDANTGEEYPRGEIPERAVAVGSSRLK
SFPGGEFAMPCILVLRTLAEGEIHDKLALNDVLREHGVAG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory