SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_011654049.1 NCBI__GCF_000009265.1:WP_011654049.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

Q54VI3 Glutamate dehydrogenase 2; NAD-specific glutamate dehydrogenase; NAD-GDH; EC 1.4.1.2 from Dictyostelium discoideum (Social amoeba) (see paper)
25% identity, 30% coverage: 688:1167/1592 of query aligns to 446:894/1042 of Q54VI3

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Q54VI3
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L

Query Sequence

>WP_011654049.1 NCBI__GCF_000009265.1:WP_011654049.1
MAARNNPKREKQIESARKIAKATGEAHLDPEILFGRASNDDLELYTPEMLALSAVHSAKE
LAAWNGKAPRVGIDTITDVTPDGIAVSVLSVTDQNMPFLFESVMGEVTSTYRDLFMAVHP
ILVMEKGKAPALYSADHPSDPANRVSHIQLHIAPLNSTQAADLVKRIEKVLEQVRLSVSD
WKPMLSKIDGVIAELAANGASRKKADRDEAVAFLTWLRDENFTFLGMREYVYSGKGAEAK
VERDKGAGLGILSNPDVLVLRTGKDAVTTTPEILAFLDGPDFLIVTKANVKSIVHRRAYM
DYVGVKRFDADGNVTGELRIVGLFTSTAYTSLASEIPLLRSKIEKVKEHFGFDPMSHSGR
MLDNTLESYPRDDLFQIDTTLLASFAEQINDLGDRPRVRVLPRIDHFDRFVSVIVYVPRE
EYDSIVRERIGTYLKTVYDGRVSAYYPAFPEGGVARVHFIIGRSGGKTPRIPQAKLEQVI
REITARWDDRFEALAGVKAPKISVDQAFQDSFTPEETVADLADIGACATGEPLRIHFYHR
QEEEQGRILSLKIFHAGGQLALSRRVPLLENLGFNVVSERTFDIGVPVADGEKKLVVLHD
MELEARNGGEIDLQRYGAALEEGFVAAFAGTIDNDSFNRLILSAGLSARETNVLRAYARY
LRQAGIPYSQDYIATTLDKYPGVAAAIFRLFHDTLDTRLTEKARVKKLAELHQAIETELA
NVPSLDDDRILRRYVNIVDATLRTNYFQKNPDGSPKPMLAFKLDPHLVDGLPEPKPFREM
FVYGVEVEGVHLRFGKVARGGLRWSDRAEDYRTEVLGLVKAQQVKNAVIVPVGAKGGFYP
KKLPVSGSRDETFNAGREAYKTYIRTLLSITDNISGADIVPPKDTVRLDGDDPYFVVAAD
KGTATFSDTANALAQEAGFWLDDAFASGGSAGYDHKKMGITARGAWETVKRHFREMDIDI
QTTPFTVAGVGDMSGDVFGNGMLLSPKIRLIAAFDHRDIVIDPDPDMEKTLTERQRLFDL
PRSSWQDFDKSVLSKGAMIISRSAKSVTLTPEAVAAIGIDKAVATPFEIMTAILKSPVDL
LWFGGIGTYVKASSETDTEVGDRANDPIRITAAEVRAKVIGEGANLGVTQKGRIAYGLKG
GRCNSDAIDNSAGVNTSDVEVNIKIALAAAMHDGRLTRVKRDQLLSSMTSEVATLVLRNN
YLQSLAISLTERKGTANGLELGRFMSVLEGAGQLNRKVETLPDDQTLAERYAAGKPLTRP
EIGVLVSYAKIVLFDALAASDLPDDPYFIATLLNYFPVKMQKSNAGDIASHRLKREIVAT
VLANEAINRGGPSFTVAMMDATAASAPEVVRAAIVARDGFDLTRLWAETDALDGKISGDL
QNRIYEEISHSFIVLTRLLLKTGMTKADMVEVISRLQAALKKLKTAFAGQVAGEVAVRQA
EYSQAGLPEKLAADIASLPIFALVPEIMQIAERTGEPLVRAAENYIAVSQTFRIGRLLAA
GGRILTSDHYENLALARSIDQIASARRDIVISALSDHGKEKLPVQAWHAQDRIRINRILE
ELSSLSDGGDPNLARITVAAGILTDLARDRAR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory