Comparing WP_011736257.1 NCBI__GCF_000015045.1:WP_011736257.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
48% identity, 100% coverage: 1:459/461 of query aligns to 2:461/464 of 4f4fA
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
46% identity, 92% coverage: 1:424/461 of query aligns to 5:465/514 of Q42598
1kl7A Crystal structure of threonine synthase from yeast (see paper)
47% identity, 91% coverage: 3:423/461 of query aligns to 7:461/509 of 1kl7A
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
37% identity, 92% coverage: 1:423/461 of query aligns to 5:442/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
35% identity, 100% coverage: 1:459/461 of query aligns to 1:427/428 of 1vb3A
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine (see paper)
24% identity, 68% coverage: 106:417/461 of query aligns to 124:406/444 of 2c2bA
Sites not aligning to the query:
Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 68% coverage: 106:417/461 of query aligns to 199:481/526 of Q9S7B5
Sites not aligning to the query:
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
25% identity, 67% coverage: 84:390/461 of query aligns to 26:328/350 of 6nmxA
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
25% identity, 67% coverage: 84:390/461 of query aligns to 24:326/345 of 6cgqB
A0R220 Threonine synthase; TS; EC 4.2.3.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
28% identity, 38% coverage: 88:261/461 of query aligns to 39:203/360 of A0R220
>WP_011736257.1 NCBI__GCF_000015045.1:WP_011736257.1
MRYISTRGGIQPINFKDAVMMGLATDGGLLLPESYPQISRQELDQWRSLSYPDLALRIIS
PFVDDIPVDDLKGLIQRSYATFNHPQVTPVVHRDGVHILELFHGVTLAFKDVALQLLGNL
FEYILAERGERLNILGATSGDTGSAAIHGVRGKKGITIFILHPHGKTSPVQALQMITVGD
ANVHNIAIRGTFDDCQNMVKALFNDLQFKEKYSLGAVNSINWARVLAQVVYYFYAWLRVT
DEGDRPVCFSVPTGNFGDIFAGYVAKRMGLPMGRLLLATNENNILTRFVRDGDYSLANVV
ATVSPSMDIQLASNFERYLFHLYDQDPGRVRAAFAELRECGRISFTPAEMEQVRADFCSA
TVDQAATLETIGSFNRETGYLLDPHTAVGVRAALDLLPSDAARVCLATAHPAKFGEAVEK
AVGTPAPVPGSIAALAGMETRCTVMDADLEKVRQFVVEHVA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory