Comparing WP_011737168.1 NCBI__GCF_000015045.1:WP_011737168.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47 from Escherichia coli (strain K12) (see paper)
46% identity, 96% coverage: 5:296/305 of query aligns to 3:292/303 of P16703
2bhtA Crystal structure of o-acetylserine sulfhydrylase b (see paper)
45% identity, 96% coverage: 5:296/305 of query aligns to 3:292/294 of 2bhtA
5xoqA Crystal structure of o-acetylserine sulfhydrylase with bound transcription factor peptide inhibitor from planctomyces limnophilus
44% identity, 95% coverage: 9:299/305 of query aligns to 11:309/310 of 5xoqA
P9WP55 O-acetylserine sulfhydrylase; OAS sulfhydrylase; OASS; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase; EC 2.5.1.47 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
43% identity, 98% coverage: 3:300/305 of query aligns to 4:309/310 of P9WP55
2q3dA 2.2 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) from mycobacterium tuberculosis in complex with the reaction intermediate alpha-aminoacrylate (see paper)
43% identity, 96% coverage: 3:296/305 of query aligns to 4:305/306 of 2q3dA
3zeiA Structure of the mycobacterium tuberculosis o-acetylserine sulfhydrylase (oass) cysk1 in complex with a small molecule inhibitor (see paper)
43% identity, 94% coverage: 4:291/305 of query aligns to 5:300/300 of 3zeiA
2q3cA 2.1 a resolution crystal structure of o-acetylserine sulfhydrylase (oass) holoenzyme from mycobacterium tuberculosis in complex with the inhibitory peptide dfsi (see paper)
43% identity, 94% coverage: 4:291/305 of query aligns to 5:300/300 of 2q3cA
2efyA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 4-acetylbutyric acid
45% identity, 94% coverage: 9:296/305 of query aligns to 6:301/302 of 2efyA
2ecqA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 3-hydroxylactate
45% identity, 94% coverage: 9:296/305 of query aligns to 6:301/302 of 2ecqA
2ecoA Crystal structure of t.Th. Hb8 o-acetylserine sulfhydrylase complexed with 4-methylvalerate
45% identity, 94% coverage: 9:296/305 of query aligns to 6:301/302 of 2ecoA
4lmbA Crystal structure analysis of o-acetylserine sulfhydrylase cysk2 complexed with cystine from microcystis aeruginosa 7806 (see paper)
43% identity, 96% coverage: 3:296/305 of query aligns to 4:308/310 of 4lmbA
4lmaA Crystal structure analysis of o-acetylserine sulfhydrylase cysk1 from microcystis aeruginosa 7806 (see paper)
43% identity, 95% coverage: 10:299/305 of query aligns to 11:311/318 of 4lmaA
8b9wA Cysteine synthase from trypanosoma theileri with plp bound (see paper)
42% identity, 95% coverage: 10:299/305 of query aligns to 17:314/329 of 8b9wA
4aecA Crystal structure of the arabidopsis thaliana o-acetyl-serine-(thiol)- lyasE C (see paper)
44% identity, 95% coverage: 10:299/305 of query aligns to 21:319/323 of 4aecA
P47999 Cysteine synthase, chloroplastic/chromoplastic; At.OAS.7-4; Beta-substituted Ala synthase 2;1; ARAth-Bsas2;1; CSase B; AtCS-B; CS-B; O-acetylserine (thiol)-lyase; O-acetylserine sulfhydrylase; OAS-TL B; cpACS1; EC 2.5.1.47 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
43% identity, 96% coverage: 10:303/305 of query aligns to 83:385/392 of P47999
Sites not aligning to the query:
5xemA Crystal structure of a hydrogen sulfide-producing enzyme (fn1220) from fusobacterium nucleatum in complex with l-lanthionine-plp schiff base
40% identity, 95% coverage: 4:292/305 of query aligns to 4:301/302 of 5xemA
Sites not aligning to the query:
4jblB Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with methionine (see paper)
38% identity, 96% coverage: 4:296/305 of query aligns to 14:318/335 of 4jblB
3bm5B Crystal structure of o-acetyl-serine sulfhydrylase from entamoeba histolytica in complex with cysteine (see paper)
38% identity, 96% coverage: 4:296/305 of query aligns to 14:318/335 of 3bm5B
4jbnA Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with serine acetyl transferase derived tetrapeptide, spsi (see paper)
38% identity, 96% coverage: 4:296/305 of query aligns to 14:318/336 of 4jbnA
4il5A Crystal structure of o-acetyl serine sulfhydrylase from entamoeba histolytica in complex with isoleucine (see paper)
38% identity, 96% coverage: 4:296/305 of query aligns to 14:318/336 of 4il5A
>WP_011737168.1 NCBI__GCF_000015045.1:WP_011737168.1
MKGQSLINAIGSTPMVEIISINPNPKVTILAKLEGNNPGGSVKDRPARQMILAAEASGEL
TREKIILEPTSGNTGIALAMIAAARGYRIKLVMPACVSVERRGVLEAYGAEIVLSPGCEA
TDGAIRLAHKIHDDAPETYFMPNQYANPHNALAHYETTAPEIMSQTEGGVTHVVAGMGTG
GTLMGIARYFREVSPNVKVIGIEPMPGHRIQGLKNMQEAIVPPIYNENALDRKIVIEDDP
AFETARLLASHEGVFCGMSGGAAMSGALRLAGELESGVIVVILPDRGDRYLSTNLFTSMC
AHCPP
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory