Comparing WP_011765402.1 NCBI__GCF_000061505.1:WP_011765402.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6agmA Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy- d-arabino-heptulosonate-7-phosphate synthase from escherichia coli (see paper)
53% identity, 97% coverage: 8:355/358 of query aligns to 5:333/334 of 6agmA
1kflA Crystal structure of phenylalanine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase (dahp synthase) from e.Coli complexed with mn2+, pep, and phe (see paper)
51% identity, 94% coverage: 5:342/358 of query aligns to 4:339/350 of 1kflA
P0AB91 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Escherichia coli (strain K12) (see paper)
51% identity, 94% coverage: 5:342/358 of query aligns to 4:339/350 of P0AB91
1gg1A Crystal structure analysis of dahp synthase in complex with mn2+ and 2-phosphoglycolate (see paper)
51% identity, 94% coverage: 8:342/358 of query aligns to 1:329/339 of 1gg1A
5cksB Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase in complex with dahp oxime. (see paper)
51% identity, 94% coverage: 7:342/358 of query aligns to 1:334/345 of 5cksB
8e0sD Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase complexed with dahp oxime in unbound:(bound)2:unbound conformations (see paper)
51% identity, 94% coverage: 8:342/358 of query aligns to 1:333/343 of 8e0sD
7rudB Dahp synthase complex with trifluoropyruvate oxime (see paper)
51% identity, 94% coverage: 8:342/358 of query aligns to 1:333/343 of 7rudB
1qr7A Crystal structure of phenylalanine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from escherichia coli complexed with pb2+ and pep (see paper)
51% identity, 93% coverage: 9:342/358 of query aligns to 1:327/338 of 1qr7A
7rueA Dahp synthase complexed with trifluoropyruvate semicarbazone (see paper)
50% identity, 94% coverage: 6:342/358 of query aligns to 1:329/339 of 7rueA
5cksA Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase in complex with dahp oxime. (see paper)
50% identity, 94% coverage: 6:342/358 of query aligns to 1:328/339 of 5cksA
8e0sA Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase complexed with dahp oxime in unbound:(bound)2:unbound conformations (see paper)
50% identity, 94% coverage: 8:342/358 of query aligns to 1:325/336 of 8e0sA
4hsoA Crystal structure of s213g variant dah7ps from neisseria meningitidis (see paper)
47% identity, 97% coverage: 6:354/358 of query aligns to 2:344/345 of 4hsoA
1ofoA Crystal structure of the tyrosine regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae in complex with 2-phosphoglycolate (see paper)
48% identity, 97% coverage: 8:356/358 of query aligns to 1:341/344 of 1ofoA
7reuB Crystal structure of aro4p, 3-deoxy-d-arabino-heptulosonate-7- phosphate (dahp) synthase from candida auris, l-tyr complex
44% identity, 99% coverage: 5:357/358 of query aligns to 2:356/358 of 7reuB
5dcdA Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated (tyrosine)
47% identity, 97% coverage: 6:354/358 of query aligns to 4:346/346 of 5dcdA
5dcbC Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated and complexed with pep
47% identity, 97% coverage: 6:354/358 of query aligns to 6:348/348 of 5dcbC
5dceA Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated (tryptophan) (see paper)
47% identity, 97% coverage: 6:354/358 of query aligns to 2:344/344 of 5dceA
1of6A Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with tyrosine and manganese
48% identity, 98% coverage: 7:356/358 of query aligns to 4:348/350 of 1of6A
3tqkA Structure of phospho-2-dehydro-3-deoxyheptonate aldolase from francisella tularensis schu s4 (see paper)
50% identity, 88% coverage: 27:342/358 of query aligns to 18:330/341 of 3tqkA
1ofrC Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with phenylalanine and manganese (see paper)
48% identity, 98% coverage: 7:356/358 of query aligns to 2:345/348 of 1ofrC
>WP_011765402.1 NCBI__GCF_000061505.1:WP_011765402.1
MSVAQTENLNIATVDHMPSPEEIKARVPLSDRAAATVLAGRKALADILEGRDKRLFVVVG
PCSIHDPVAGLDYARRLKALADEVSDTMLLVMRVYFEKPRTSTGWKGFINDPFMDDSFRI
DVGMEKARRFLLDVCEIGLPTGTEALDPNAPQYYGDLVTWTAIGARTSESQTHREMASGL
STPVGFKNATDGDLEVAINAIISAAHPHSFLGINGQGQSAILRTRGNRHGHVVLRGGGGR
PNYDTVSVSLAEQALAKAKLPVNIVVDCSHANSWKKPELQPLVMKDVIHQIREGNRSVVG
LMIESNLEAGNQAIPADLSQLKYGCSVTDACVGWDTTVDMIRSAHGVLRDALARRERA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory