Comparing WP_011813685.1 NCBI__GCF_000015585.1:WP_011813685.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
O53289 Phosphoserine phosphatase SerB2; PSP; PSPase; O-phosphoserine phosphohydrolase; Protein-serine/threonine phosphatase; EC 3.1.3.3; EC 3.1.3.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
25% identity, 88% coverage: 5:203/227 of query aligns to 183:365/409 of O53289
Sites not aligning to the query:
8a21A Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with phenylimidazole (see paper)
27% identity, 88% coverage: 5:203/227 of query aligns to 181:363/396 of 8a21A
Sites not aligning to the query:
8a1zA Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea (see paper)
27% identity, 88% coverage: 5:203/227 of query aligns to 181:363/396 of 8a1zA
A0QJI1 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Mycobacterium avium (strain 104) (see paper)
27% identity, 88% coverage: 5:203/227 of query aligns to 185:367/411 of A0QJI1
5jlpA Crystal structure of mycobacterium avium serb2 in complex with serine at act domain
27% identity, 88% coverage: 5:203/227 of query aligns to 181:363/396 of 5jlpA
Sites not aligning to the query:
>WP_011813685.1 NCBI__GCF_000015585.1:WP_011813685.1
MSVALFDLDNTLIAGDSDSLWGEYLVACGAVDSEAFAETHRRFHQDYIEGRLDIDAFLAF
ALSPLAQHPEEQLHAWRADFTRDWIEPLVLPAAEALLEEHRRAGHHLAIVTATNRFVTAP
IAERLDVGTLLATEPERRDGRYTGRHTGTPTFREGKIRVVEAWLREHGLEQAEKWFYSDS
LNDLPLLRHVEHPVAVDPDDTLRAEARRNGWPVLTLRQAETPECCSA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory