Comparing WP_011814644.1 NCBI__GCF_000015585.1:WP_011814644.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
31% identity, 77% coverage: 13:274/341 of query aligns to 8:286/364 of P97084
Sites not aligning to the query:
1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica (see paper)
30% identity, 77% coverage: 13:274/341 of query aligns to 1:279/355 of 1lkcA
Sites not aligning to the query:
1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate (see paper)
30% identity, 77% coverage: 13:274/341 of query aligns to 2:280/356 of 1lc8A
Sites not aligning to the query:
1lc7A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
30% identity, 77% coverage: 13:274/341 of query aligns to 5:283/358 of 1lc7A
Sites not aligning to the query:
4wbtA Crystal structure of histidinol-phosphate aminotransferase from sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
31% identity, 50% coverage: 141:309/341 of query aligns to 158:333/369 of 4wbtA
Sites not aligning to the query:
7szpA Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
34% identity, 33% coverage: 139:249/341 of query aligns to 146:256/353 of 7szpA
Sites not aligning to the query:
1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate (see paper)
34% identity, 33% coverage: 139:249/341 of query aligns to 132:242/335 of 1geyA
Sites not aligning to the query:
1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate (see paper)
34% identity, 33% coverage: 139:249/341 of query aligns to 146:256/354 of 1fg7A
Sites not aligning to the query:
1fg3A Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
34% identity, 33% coverage: 139:249/341 of query aligns to 146:256/354 of 1fg3A
Sites not aligning to the query:
3ly1D Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
25% identity, 67% coverage: 110:338/341 of query aligns to 119:335/354 of 3ly1D
Sites not aligning to the query:
2o1bA Structure of aminotransferase from staphylococcus aureus
26% identity, 66% coverage: 80:303/341 of query aligns to 87:330/376 of 2o1bA
5yhvA Crystal structure of an aminotransferase from mycobacterium tuberculosis
26% identity, 72% coverage: 87:330/341 of query aligns to 112:382/394 of 5yhvA
Sites not aligning to the query:
P96847 Valine--pyruvate aminotransferase; Alanine--valine transaminase; EC 2.6.1.66 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
26% identity, 72% coverage: 87:330/341 of query aligns to 106:376/388 of P96847
5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
26% identity, 72% coverage: 87:330/341 of query aligns to 105:375/387 of 5yhvB
Sites not aligning to the query:
Q0ZQ41 CMP-5'-(3-aminopropyl)phosphonate synthase; EC 2.7.7.-; EC 4.1.1.- from Streptomyces rubellomurinus (strain ATCC 31215) (see paper)
30% identity, 52% coverage: 82:257/341 of query aligns to 337:525/628 of Q0ZQ41
Sites not aligning to the query:
4r8dA Crystal structure of rv1600 encoded aminotransferase in complex with plp-mes from mycobacterium tuberculosis
28% identity, 54% coverage: 139:323/341 of query aligns to 163:339/369 of 4r8dA
Sites not aligning to the query:
4r5zA Crystal structure of rv3772 encoded aminotransferase (see paper)
28% identity, 55% coverage: 141:327/341 of query aligns to 150:339/353 of 4r5zA
Sites not aligning to the query:
4r2nA Crystal structure of rv3772 in complex with its substrate (see paper)
28% identity, 55% coverage: 141:327/341 of query aligns to 150:339/353 of 4r2nA
Sites not aligning to the query:
>WP_011814644.1 NCBI__GCF_000015585.1:WP_011814644.1
MAEQHPLPRMEEHGGNLDQATARFGLPREGWVDLSTGINPTPFPLTPAPDAAWHRLPEAD
DLEARAAEHYRAGNNAALALPGSQAAISLLPALEPPGYVAIPAPEYAEHARAWQRWGHRV
ERLTADCIAAGPPRRLPWQTMVLSHPNNPTGTRHSAATLLAWCDALAAEGGQLIVDEAFC
DAEPETSLAPSAGRPGLVLLRSLGKFYGLAGARVGFLLGPQALRQRLADLLGPWPVAGPA
RHAARQALADSAWQDRQRHVLAASSERLDHLLTRAGLAPTGGTALFRWTPCHDARQRQAE
LARAGIWVRAFDAPAGLRFGLPGPESDWQRLAAALGCPPGD
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory