Comparing WP_011841302.1 NCBI__GCF_000015985.1:WP_011841302.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form.
34% identity, 93% coverage: 9:368/387 of query aligns to 8:361/381 of 8uw6B
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
29% identity, 96% coverage: 11:382/387 of query aligns to 12:362/366 of Q8P8J5
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
29% identity, 96% coverage: 11:382/387 of query aligns to 13:357/360 of 2f7vA
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
27% identity, 78% coverage: 70:371/387 of query aligns to 72:367/383 of 7uoiA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
27% identity, 82% coverage: 70:385/387 of query aligns to 64:374/377 of 7t1qA
7lgpB Dape enzyme from shigella flexneri
28% identity, 82% coverage: 68:385/387 of query aligns to 63:375/377 of 7lgpB
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
29% identity, 57% coverage: 67:286/387 of query aligns to 98:319/426 of 3pfoA
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
25% identity, 83% coverage: 66:386/387 of query aligns to 73:399/408 of Q03154
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
27% identity, 56% coverage: 66:283/387 of query aligns to 73:291/407 of P37111
Sites not aligning to the query:
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
31% identity, 47% coverage: 68:250/387 of query aligns to 66:248/380 of 5vo3A
Sites not aligning to the query:
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
31% identity, 47% coverage: 68:250/387 of query aligns to 62:244/377 of P44514
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
29% identity, 51% coverage: 68:263/387 of query aligns to 62:258/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
29% identity, 51% coverage: 68:263/387 of query aligns to 62:258/375 of 4pqaA
Sites not aligning to the query:
Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human)
42% identity, 21% coverage: 67:148/387 of query aligns to 93:177/475 of Q96KP4
Sites not aligning to the query:
Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 2 papers)
41% identity, 21% coverage: 67:148/387 of query aligns to 93:177/475 of Q9D1A2
Sites not aligning to the query:
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
41% identity, 21% coverage: 67:148/387 of query aligns to 97:181/478 of 2zogA
Sites not aligning to the query:
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
41% identity, 21% coverage: 67:148/387 of query aligns to 97:181/478 of 2zofA
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
37% identity, 30% coverage: 68:182/387 of query aligns to 64:187/258 of 4h2kA
Sites not aligning to the query:
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
29% identity, 48% coverage: 8:193/387 of query aligns to 52:260/503 of Q8C165
Sites not aligning to the query:
1q7lA Zn-binding domain of the t347g mutant of human aminoacylase-i (see paper)
38% identity, 19% coverage: 66:140/387 of query aligns to 67:144/192 of 1q7lA
Sites not aligning to the query:
>WP_011841302.1 NCBI__GCF_000015985.1:WP_011841302.1
MPSLLTPRQILERLVAFPTVSRDSNLALVDWVEEFLEGAGITAHRVWNEERTKAALYAHV
GPEVDGAVVLSGHTDVVPVEGQDWSSDPWTLTERDGRLYGRGTCDMKGFDALALAALALA
QETGVKRPLQIALSFDEEVGCLGAPAMIDEMARCLPKGRAVIVGEPSRMQVVTGHKGGGG
LICQVQGHEVHSSIMHRGVNAIMSAARLIDWANRRNAQSAAARPSEVAALFDPPWTTVHV
GTIRGGTAGNITARDCRFDMGFRAVPGETVEEWAAAFEAEAQALEAEMKAIHPEAAIRIA
RLFGYPPLRPETEGAAEALARRLSGDNGTHVVSYGTEAGQFQAAGYSAVVCGPGDIAQAH
QPDEYLEVAQFEEGWTFLQRLVADLAR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory