Comparing WP_011841308.1 NCBI__GCF_000015985.1:WP_011841308.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q56YA5 Serine--glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase; AGT; Asparagine aminotransferase; Serine--pyruvate aminotransferase; EC 2.6.1.45; EC 2.6.1.44; EC 2.6.1.-; EC 2.6.1.51 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
34% identity, 98% coverage: 6:395/400 of query aligns to 8:388/401 of Q56YA5
6pk3B Alanine-glyoxylate aminotransferase 1 (agt1) from arabidopsis thaliana (see paper)
34% identity, 98% coverage: 6:395/400 of query aligns to 7:387/400 of 6pk3B
6pk1A Alanine-glyoxylate aminotransferase 1 (agt1) from arabidopsis thaliana in presence of serine (see paper)
34% identity, 98% coverage: 6:395/400 of query aligns to 6:386/399 of 6pk1A
2huuA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase in complex with alanine (see paper)
34% identity, 70% coverage: 13:290/400 of query aligns to 25:303/385 of 2huuA
Sites not aligning to the query:
2huiA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase in complex with glyoxylic acid (see paper)
34% identity, 70% coverage: 13:290/400 of query aligns to 25:303/385 of 2huiA
Sites not aligning to the query:
2hufA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase (see paper)
34% identity, 70% coverage: 13:290/400 of query aligns to 25:303/385 of 2hufA
Sites not aligning to the query:
Q3LSM4 Alanine--glyoxylate aminotransferase; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (see paper)
34% identity, 70% coverage: 13:290/400 of query aligns to 25:303/393 of Q3LSM4
Sites not aligning to the query:
Q7PRG3 3-hydroxykynurenine transaminase; AgHKT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Anopheles gambiae (African malaria mosquito) (see paper)
29% identity, 70% coverage: 13:290/400 of query aligns to 24:302/396 of Q7PRG3
6mfbD Crystal structure of 3-hydroxykynurenine transaminase from aedes aegypti
28% identity, 75% coverage: 13:312/400 of query aligns to 24:319/386 of 6mfbD
2ch2A Structure of the anopheles gambiae 3-hydroxykynurenine transaminase in complex with inhibitor (see paper)
28% identity, 70% coverage: 13:290/400 of query aligns to 22:300/387 of 2ch2A
Sites not aligning to the query:
2ch1A Structure of anopheles gambiae 3-hydroxykynurenine transaminase (see paper)
29% identity, 70% coverage: 13:290/400 of query aligns to 23:301/388 of 2ch1A
Q0IG34 3-hydroxykynurenine transaminase; 3-hydroxykynurenine transaminase and alanine--glyoxylate aminotransferase; Ae-HKT/AGT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
28% identity, 75% coverage: 13:312/400 of query aligns to 24:319/400 of Q0IG34
1vjoA Crystal structure of alanine--glyoxylate aminotransferase (alr1004) from nostoc sp. At 1.70 a resolution (see paper)
29% identity, 70% coverage: 13:290/400 of query aligns to 24:299/377 of 1vjoA
2bkwA Yeast alanine:glyoxylate aminotransferase yfl030w (see paper)
27% identity, 68% coverage: 10:279/400 of query aligns to 6:288/381 of 2bkwA
Sites not aligning to the query:
1j04A Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro (see paper)
26% identity, 75% coverage: 13:313/400 of query aligns to 25:321/387 of 1j04A
Sites not aligning to the query:
2dr1A Crystal structure of the ph1308 protein from pyrococcus horikoshii ot3
27% identity, 76% coverage: 58:362/400 of query aligns to 68:357/381 of 2dr1A
1iugA The crystal structure of aspartate aminotransferase which belongs to subgroup iv from thermus thermophilus (see paper)
29% identity, 90% coverage: 9:368/400 of query aligns to 2:335/348 of 1iugA
1h0cA The crystal structure of human alanine:glyoxylate aminotransferase (see paper)
26% identity, 75% coverage: 13:313/400 of query aligns to 25:319/385 of 1h0cA
Sites not aligning to the query:
3zrrA Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from sulfolobus solfataricus (see paper)
27% identity, 96% coverage: 14:398/400 of query aligns to 5:379/379 of 3zrrA
Sites not aligning to the query:
3zrqA Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from sulfolobus solfataricus (see paper)
27% identity, 96% coverage: 14:398/400 of query aligns to 8:382/382 of 3zrqA
>WP_011841308.1 NCBI__GCF_000015985.1:WP_011841308.1
MSLAHGRPYLAIPGPSAMPDRVLNAMHRAAPNIYEGALHEMVASLWPDLKRIAGTEHQVA
LYIANGHGAWEAANANLFSRGDRALVLATGRFGHGWAESARALGVDVQLIDFGRAAPADP
ARLEEALRADPGHRIKAVLVTHVDTATSIRNDVAALRAAIDAVGHPALLAVDCIASLACD
EYRMDEWGADVTVGASQKGLMTPPGLGFVWYSDRALERCRASDLRTPYWDWTPRSFGTEF
WQHFCGTAPTHHLYGLRAALDMILEEGLPAVWARHEALARAVWTAFDRWGAGNPEIALNV
ADAACRGRSVTAARMGAPHATRLREWTETRAGVTLGIGLGMALPSEPAYHGFLRVAHMGH
VNAHMTLGALAVMEAGLAALEIPHGEGALAAAAASLGAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory