Comparing WP_011842332.1 NCBI__GCF_000015985.1:WP_011842332.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1eyyA Crystal structure of the NADP+ dependent aldehyde dehydrogenase from vibrio harveyi. (see paper)
49% identity, 93% coverage: 37:507/508 of query aligns to 19:487/504 of 1eyyA
P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; FBP-CI; EC 1.5.1.6 from Rattus norvegicus (Rat) (see 5 papers)
30% identity, 59% coverage: 14:313/508 of query aligns to 425:716/902 of P28037
Sites not aligning to the query:
4go2A Crystal structure of thE C-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with thio-NADP (see paper)
30% identity, 59% coverage: 14:313/508 of query aligns to 21:312/498 of 4go2A
Sites not aligning to the query:
2o2rA Crystal structure of thE C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH (see paper)
30% identity, 59% coverage: 14:313/508 of query aligns to 21:312/498 of 2o2rA
Sites not aligning to the query:
7rluA Structure of aldh1l1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP (see paper)
30% identity, 59% coverage: 14:313/508 of query aligns to 106:397/583 of 7rluA
Sites not aligning to the query:
2d4eC Crystal structure of the hpcc from thermus thermophilus hb8
28% identity, 90% coverage: 13:470/508 of query aligns to 29:490/515 of 2d4eC
4neaA 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
26% identity, 87% coverage: 12:454/508 of query aligns to 19:456/505 of 4neaA
Sites not aligning to the query:
3ty7B Crystal structure of aldehyde dehydrogenase family protein from staphylococcus aureus
29% identity, 64% coverage: 10:332/508 of query aligns to 5:307/454 of 3ty7B
Sites not aligning to the query:
4cazA Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
29% identity, 58% coverage: 12:306/508 of query aligns to 7:287/489 of 4cazA
Sites not aligning to the query:
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct. (see paper)
29% identity, 58% coverage: 12:306/508 of query aligns to 7:287/489 of 2woxA
Sites not aligning to the query:
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa (see paper)
29% identity, 58% coverage: 12:306/508 of query aligns to 7:287/489 of 2wmeA
Sites not aligning to the query:
Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
29% identity, 58% coverage: 12:306/508 of query aligns to 8:288/490 of Q9HTJ1
Sites not aligning to the query:
O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Homo sapiens (Human) (see 2 papers)
28% identity, 54% coverage: 60:332/508 of query aligns to 477:734/902 of O75891
Sites not aligning to the query:
7yjjC Human cytosolic 10-formyltetrahydrofolate dehydrogenase and gossypol complex (see paper)
29% identity, 65% coverage: 5:332/508 of query aligns to 13:330/498 of 7yjjC
Sites not aligning to the query:
P25526 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli (strain K12) (see paper)
30% identity, 60% coverage: 3:305/508 of query aligns to 5:290/482 of P25526
Sites not aligning to the query:
3jz4A Crystal structure of e. Coli NADP dependent enzyme (see paper)
30% identity, 60% coverage: 3:305/508 of query aligns to 4:289/481 of 3jz4A
Sites not aligning to the query:
4yweA Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
27% identity, 94% coverage: 12:488/508 of query aligns to 2:475/476 of 4yweA
8vr1A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (ctp bound)
29% identity, 58% coverage: 10:306/508 of query aligns to 10:286/488 of 8vr1A
Sites not aligning to the query:
8vr0A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (gmp bound)
29% identity, 58% coverage: 10:306/508 of query aligns to 10:286/488 of 8vr0A
Sites not aligning to the query:
8vqzA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (cmp bound)
29% identity, 58% coverage: 10:306/508 of query aligns to 10:286/488 of 8vqzA
Sites not aligning to the query:
>WP_011842332.1 NCBI__GCF_000015985.1:WP_011842332.1
MLDTSVFTPHGKHLIAGEWVAGETSFTSDPAHGPSHAFSVGTPDLVDRACRAAEEAFWTY
GQTTRESRAAFLRAIADEIEARAEAITEIGRRETGLPEARLQGERGRTIGQLRLFAEHIL
EGGHLDRRHDVALPERQPLPRPDIRLVMRPIGPIAVFGASNFPLAFSTAGGDTAAALAAG
CPVVVKGHGAHPGTAEIVAEAILAAIRKTGMPDGVFSLIQGGRRDVGQALVQHPLIAAVG
FTGSLKGGRALFDLCAQREVPIPFFGELGSVNPMFLLPEAVKARGAAIGAGWAASLTMGA
GQFCTNPGIAVVEIGPEGDAFVAAAAEALRAVPAQCMLTPDIAQAYRKGRSRFDGRPDVR
PVLTTDSDGRNALPNLFETDAASYLRDPALGEEVFGPLGLVVRVSGADEVDALARGLEGQ
LTATIHMDEGDTALAQRLMPVLERKAGRLLVNGFPTGVEVSHAMVHGGPYPASTNFGATS
VGTLSIRRFLRPVSYQNLPPALLPRDLA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory