Comparing WP_011879826.1 NCBI__GCF_000016205.1:WP_011879826.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
33% identity, 93% coverage: 23:382/387 of query aligns to 29:377/381 of 8uw6B
Sites not aligning to the query:
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
28% identity, 83% coverage: 67:386/387 of query aligns to 62:377/377 of P44514
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
28% identity, 82% coverage: 67:383/387 of query aligns to 66:378/380 of 5vo3A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
32% identity, 78% coverage: 67:369/387 of query aligns to 62:360/375 of 4pqaA
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
31% identity, 81% coverage: 67:381/387 of query aligns to 62:376/376 of 4o23A
7lgpB Dape enzyme from shigella flexneri
34% identity, 50% coverage: 67:260/387 of query aligns to 63:259/377 of 7lgpB
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
28% identity, 82% coverage: 67:384/387 of query aligns to 70:383/383 of 7uoiA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
32% identity, 54% coverage: 69:276/387 of query aligns to 64:274/377 of 7t1qA
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
32% identity, 49% coverage: 67:256/387 of query aligns to 99:289/426 of 3pfoA
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
43% identity, 26% coverage: 67:166/387 of query aligns to 64:167/258 of 4h2kA
Sites not aligning to the query:
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
27% identity, 96% coverage: 10:381/387 of query aligns to 13:358/360 of 2f7vA
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
30% identity, 56% coverage: 65:280/387 of query aligns to 73:295/407 of P37111
Sites not aligning to the query:
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
27% identity, 96% coverage: 10:381/387 of query aligns to 12:363/366 of Q8P8J5
4mmoA The crystal structure of a m20 family metallo-carboxypeptidase sso-cp2 from sulfolobus solfataricus
33% identity, 44% coverage: 47:215/387 of query aligns to 44:222/437 of 4mmoA
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
36% identity, 32% coverage: 45:166/387 of query aligns to 51:165/265 of 4op4B
Sites not aligning to the query:
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
27% identity, 56% coverage: 65:280/387 of query aligns to 73:296/408 of Q03154
Sites not aligning to the query:
3rzaA Crystal structure of a tripeptidase (sav1512) from staphylococcus aureus subsp. Aureus mu50 at 2.10 a resolution
24% identity, 82% coverage: 69:384/387 of query aligns to 74:371/373 of 3rzaA
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
26% identity, 55% coverage: 63:276/387 of query aligns to 82:351/458 of 2pokA
Sites not aligning to the query:
3dljA Crystal structure of human carnosine dipeptidase 1
37% identity, 23% coverage: 64:153/387 of query aligns to 93:185/471 of 3dljA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
37% identity, 23% coverage: 64:153/387 of query aligns to 124:216/507 of Q96KN2
Sites not aligning to the query:
>WP_011879826.1 NCBI__GCF_000016205.1:WP_011879826.1
MSDTSSRMLLARLVGFATVSRDSNLAMIDFIRDYLDGYGVTSELFYNAEGTKASLYATIG
PRDRSGIALSGHTDVVPVDGQAWTVEPFRLTERDGRLYGRGTADMKGFIASMLAAVPALV
ARPLHTPVHLLLSYDEEIGCVGVRPMLEALAGREHRPRVCVIGEPTGLQPVLGHKGKLAM
RCHVKGAACHSAYAPLGVNAIDYAAKLIARLGEIGAALARPEHRDERFDPPFSTVQTGLI
SGGRALNIVPAECEFDFEVRALPSFDAHDVPSQLQQYAQGELLPRMRAVQPDTDIRLQAL
GAYPGLATAPDSDAARLIAMLSGSDAFGTVAFGTEGGLFGAAGMPTVVCGPGSMDQGHKP
DEFVTLEQLHGCDAMLGRLVSHVAASA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory