Comparing WP_011881757.1 NCBI__GCF_000016205.1:WP_011881757.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5bntC X-ray crystal structure of a aspartate-semialdehyde dehydrogenase bound to NADP from pseudomonas aeruginosa
73% identity, 99% coverage: 3:373/373 of query aligns to 5:371/371 of 5bntC
7tcmA Crystal structure of aspartate-semialdehyde dehydrogenase from acinetobacter baumannii in complex with NADP
72% identity, 100% coverage: 1:372/373 of query aligns to 3:370/373 of 7tcmA
3pzrA Crystals structure of aspartate beta-semialdehyde dehydrogenase from vibrio cholerae with NADP and product of s-carbamoyl-l-cysteine (see paper)
69% identity, 99% coverage: 1:371/373 of query aligns to 1:367/370 of 3pzrA
Q9KQG2 Aspartate-semialdehyde dehydrogenase 1; ASA dehydrogenase 1; ASADH 1; Aspartate-beta-semialdehyde dehydrogenase 1; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
69% identity, 99% coverage: 1:371/373 of query aligns to 1:367/370 of Q9KQG2
4r5mA Crystal structure of vc-aspartate beta-semialdehyde-dehydrogenase with NADP and 4-nitro-2-phosphono-benzoic acid (see paper)
69% identity, 99% coverage: 1:371/373 of query aligns to 1:367/369 of 4r5mA
1mb4A Crystal structure of aspartate semialdehyde dehydrogenase from vibrio cholerae with NADP and s-methyl-l-cysteine sulfoxide (see paper)
69% identity, 99% coverage: 1:371/373 of query aligns to 1:367/369 of 1mb4A
1gl3A Aspartate beta-semialdehyde dehydrogenase in complex with NADP and substrate analogue s-methyl cysteine sulfoxide (see paper)
69% identity, 99% coverage: 2:370/373 of query aligns to 3:366/367 of 1gl3A
P0A9Q9 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Escherichia coli (strain K12) (see 2 papers)
69% identity, 99% coverage: 2:370/373 of query aligns to 3:366/367 of P0A9Q9
P44801 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
68% identity, 99% coverage: 2:371/373 of query aligns to 3:370/371 of P44801
1pquA Crystal structure of the h277n mutant of aspartate semialdehyde dehydrogenase from haemophilus influenzae bound with NADP, s-methyl cysteine sulfoxide and cacodylate (see paper)
67% identity, 99% coverage: 2:371/373 of query aligns to 3:370/371 of 1pquA
1tb4A Crystal structure of aspartate-semialdehyde dehydrogenase from haemophilus influenzae with a bound periodate (see paper)
66% identity, 99% coverage: 2:371/373 of query aligns to 3:356/357 of 1tb4A
1ta4A Crystal structure of aspartate-semialdehyde dehydrogenase from haemophilus influenzae with a bound arsenate (see paper)
66% identity, 99% coverage: 2:371/373 of query aligns to 3:356/357 of 1ta4A
1nx6A Crystal structure of aspartate semialdehyde dehydrogenase from haemophilus influenzae as a tetrahedral hemithiocetal reaction intermediate with phosphate at 2.15 a (see paper)
66% identity, 99% coverage: 2:371/373 of query aligns to 3:356/357 of 1nx6A
1pqpA Crystal structure of the c136s mutant of aspartate semialdehyde dehydrogenase from haemophilus influenzae bound with aspartate semialdehyde and phosphate (see paper)
66% identity, 99% coverage: 2:371/373 of query aligns to 3:356/357 of 1pqpA
8jusA Crystal structure of aspartate semialdehyde dehydrogenase from porphyromonas gingivalis complexed with 2',5'adenosine diphosphate
28% identity, 97% coverage: 1:360/373 of query aligns to 1:319/335 of 8jusA
3tz6A Crystal structure of aspartate semialdehyde dehydrogenase complexed with inhibitor smcs (cys) and phosphate from mycobacterium tuberculosis h37rv (see paper)
28% identity, 97% coverage: 1:360/373 of query aligns to 2:330/342 of 3tz6A
Sites not aligning to the query:
Q04797 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Bacillus subtilis (strain 168) (see paper)
25% identity, 97% coverage: 1:360/373 of query aligns to 5:330/346 of Q04797
P23247 Aspartate-semialdehyde dehydrogenase 2; ASA dehydrogenase 2; ASADH 2; Aspartate-beta-semialdehyde dehydrogenase 2; EC 1.2.1.11 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
24% identity, 99% coverage: 1:371/373 of query aligns to 5:333/337 of P23247
2r00C Crystal structure of aspartate semialdehyde dehydrogenase ii complexed with asa from vibrio cholerae (see paper)
24% identity, 99% coverage: 1:371/373 of query aligns to 4:332/336 of 2r00C
4r51A Crystal complex structure of sp-aspartate-semialdehyde-dehydrogenase with nicotinamide adenine dinucleotide phosphate and phthalic acid (see paper)
25% identity, 96% coverage: 2:360/373 of query aligns to 3:330/360 of 4r51A
>WP_011881757.1 NCBI__GCF_000016205.1:WP_011881757.1
MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNTGGKAPSFAKNETTLKDATNVD
ELKKCDVIITCQGGDYTNEVFPKLRAAGWNGYWIDAASSLRMNDDAVIILDPVNLDVIKD
ALVKGTKNFVGGNCTVSLMLMALGGLFRENLVDWMTAMTYQAASGAGAQNMRELLSQMGA
LHGSVEQQLADPASAILDIDRRVLATMNSDAMPTSQFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAETNKILGKPAMGQPGSIPVDGLCVRIGAMRCHSQALTIKLKKDVPLDEINGILA
SANDWVKVVPNEREASMRDLSPAKITGTLTVPVGRLRKLAMGGEYLSAFTVGDQLLWGAA
EPLRRMLRILLDK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory