SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_011883536.1 NCBI__GCF_000016205.1:WP_011883536.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

5u2kA Crystal structure of galactoside o-acetyltransferase complex with coa (h3 space group)
37% identity, 55% coverage: 71:182/202 of query aligns to 74:188/190 of 5u2kA

query
sites
5u2kA
N
 
N
V
 
V
R
 
K
I
 
L
G
 
G
D
 
K
N
 
N
C
 
V
V
 
Y
L
 
V
N
 
N
R
 
T
E
 
N
I
 
C
Y
 
Y
L
 
F
D
x
M
G
 
D
R
 
G
T
 
G
G
 
Q
I
 
I
E
 
T
I
 
I
G
 
G
N
 
D
N
 
N
V
 
V
N
 
F
I
 
I
S
 
G
F
 
P
Q
 
N
C
 
C
C
 
G
L
 
F
L
x
Y
S
 
T
L
x
A
H
 
T
H
|
H
D
 
P
-
 
L
-
 
N
-
 
F
-
 
H
H
 
H
N
 
R
H
 
N
P
 
E
G
 
G
F
 
F
M
 
E
S
 
K
I
 
A
G
 
G
G
 
P
I
 
I
V
 
-
T
 
H
I
 
I
H
 
G
D
 
S
H
 
N
A
 
T
W
 
W
L
 
F
G
 
G
A
 
G
R
 
H
A
 
V
I
 
A
I
 
V
L
|
L
P
 
P
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
E
G
 
G
A
 
S
V
 
V
V
 
I
A
 
G
A
 
A
G
 
G
A
 
S
V
 
V
V
 
V
T
|
T
K
|
K
D
 
D
V
 
I
P
 
P
D
 
P
F
 
H
T
 
S
V
 
L
V
 
A
G
 
V
G
 
G
V
 
N
P
 
P
A
 
C
K
 
K
I
 
V
I
 
V
G
 
R
Q
 
K
R
 
I
N
 
D
P
 
N
D
 
D
V
 
L

3igjC Crystal structure of maltose o-acetyltransferase complexed with acetyl coenzyme a from bacillus anthracis
38% identity, 61% coverage: 52:175/202 of query aligns to 74:183/188 of 3igjC

query
sites
3igjC
G
 
G
Q
 
Y
R
 
N
T
 
I
H
 
H
V
 
V
S
 
G
M
 
-
R
 
K
Q
 
S
F
 
F
F
|
F
T
 
A
G
 
N
Y
 
F
H
 
N
T
 
C
R
 
V
-
 
I
-
 
L
-
 
D
-
 
V
C
 
C
N
 
E
V
 
V
R
 
R
I
 
I
G
 
G
D
 
D
N
 
H
C
 
C
V
 
M
L
 
F
N
x
A
R
 
P
E
 
G
I
 
V
Y
 
H
L
 
I
D
x
Y
G
 
T
R
x
A
T
 
T
G
 
-
I
 
-
E
 
-
I
 
-
G
 
-
N
 
-
N
 
-
V
 
-
N
 
-
I
 
-
S
 
-
F
 
-
Q
 
-
C
 
-
C
 
-
L
 
-
L
x
H
S
 
P
L
 
L
H
 
H
H
 
P
D
 
V
H
 
E
N
 
R
H
 
N
P
 
S
G
 
G
F
 
-
M
 
K
S
 
E
I
 
Y
G
 
G
G
 
K
I
 
P
V
 
V
T
 
K
I
 
I
H
 
G
D
 
N
H
 
N
A
 
V
W
 
W
L
 
V
G
|
G
A
 
G
R
 
G
A
 
A
I
 
I
I
 
I
L
x
N
P
 
P
G
 
G
V
 
V
T
 
S
I
 
I
G
 
G
K
 
D
G
 
N
A
 
A
V
 
V
V
 
I
A
|
A
A
x
S
G
 
G
A
 
A
V
 
V
V
 
V
T
|
T
K
 
K
D
 
D
V
 
V
P
 
P
D
 
N
F
 
N
T
 
V
V
 
V
V
 
V
G
 
G
G
 
G
V
x
N
P
 
P
A
 
A
K
 
K
I
 
V
I
 
I

4isxA The crystal structure of maltose o-acetyltransferase from clostridium difficile 630 in complex with acetyl-coa
35% identity, 58% coverage: 60:177/202 of query aligns to 59:183/186 of 4isxA

query
sites
4isxA
R
 
K
Q
 
Q
F
 
I
F
 
N
T
 
V
G
 
E
Y
 
Q
H
 
N
T
 
I
R
 
R
C
 
C
-
 
D
-
 
Y
-
 
G
-
 
Y
N
 
N
V
 
I
R
 
H
I
 
V
G
 
G
D
 
E
N
 
N
C
 
F
V
 
F
L
 
A
N
|
N
R
 
Y
E
 
D
-
 
C
I
 
I
Y
 
F
L
 
L
D
 
D
G
 
-
R
 
V
T
 
C
G
 
K
I
 
I
E
 
E
I
 
I
G
 
G
N
 
D
N
 
N
V
 
V
N
 
M
I
 
L
S
x
A
F
 
P
Q
 
N
C
 
V
C
 
Q
L
 
I
L
 
Y
S
 
T
L
 
A
H
 
Y
H
 
H
D
 
P
H
 
I
N
 
D
-
 
A
-
 
Q
-
 
L
H
 
R
P
 
N
G
 
S
F
 
G
M
 
I
S
 
E
I
 
Y
G
 
G
G
 
S
I
 
P
V
 
V
T
 
K
I
 
I
H
 
G
D
 
D
H
 
N
A
 
V
W
|
W
L
 
I
G
|
G
A
x
G
R
 
G
A
 
V
I
 
I
I
 
I
L
 
T
P
 
P
G
 
G
V
 
I
T
 
T
I
 
I
G
 
G
K
 
D
G
 
N
A
 
V
V
 
V
V
 
I
A
 
G
A
|
A
G
 
G
A
 
S
V
 
V
V
 
V
T
 
T
K
 
K
D
 
D
V
 
I
P
 
P
D
 
P
F
 
N
T
 
T
V
 
V
V
 
A
G
x
V
G
 
G
V
 
N
P
 
P
A
 
C
K
 
R
I
 
V
I
 
I
G
x
K
Q
 
K

1krvA Galactoside acetyltransferase in complex with coa and pnp-beta-gal (see paper)
34% identity, 54% coverage: 70:179/202 of query aligns to 73:185/201 of 1krvA

query
sites
1krvA
C
 
S
N
 
N
V
 
I
R
 
H
I
 
I
G
 
G
D
 
R
N
 
N
C
 
F
V
x
Y
L
 
A
N
|
N
R
 
F
E
 
N
I
 
L
Y
 
T
L
 
I
D
x
V
G
 
D
R
x
D
T
 
Y
G
 
T
I
 
V
E
 
T
I
 
I
G
 
G
N
 
D
N
 
N
V
 
V
-
 
L
-
 
I
-
x
A
-
 
P
N
 
N
I
 
V
S
 
T
F
 
L
Q
x
S
C
 
V
C
x
T
L
 
G
L
 
H
S
 
P
L
 
V
H
 
H
H
 
H
D
 
E
H
 
L
N
 
R
H
 
K
P
 
N
G
 
G
F
 
E
M
|
M
S
 
-
I
 
Y
G
 
S
G
 
F
I
 
P
V
 
I
T
 
T
I
 
I
H
 
G
D
 
N
H
 
N
A
 
V
W
|
W
L
 
I
G
|
G
A
x
S
R
 
H
A
 
V
I
 
V
I
 
I
L
x
N
P
 
P
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
D
G
 
N
A
 
S
V
 
V
V
 
I
A
 
G
A
|
A
G
 
G
A
 
S
V
 
I
V
 
V
T
 
T
K
 
K
D
 
D
V
 
I
P
 
P
D
 
P
F
 
N
T
 
V
V
 
V
V
 
A
G
 
A
G
 
G
V
 
V
P
|
P
A
 
C
K
x
R
I
 
V
I
 
I
G
x
R
Q
 
E
R
 
I
N
 
N

Sites not aligning to the query:

1kruA Galactoside acetyltransferase in complex with iptg and coenzyme a (see paper)
34% identity, 54% coverage: 70:179/202 of query aligns to 73:185/201 of 1kruA

query
sites
1kruA
C
 
S
N
 
N
V
 
I
R
 
H
I
 
I
G
 
G
D
 
R
N
 
N
C
 
F
V
x
Y
L
 
A
N
|
N
R
 
F
E
 
N
I
 
L
Y
 
T
L
 
I
D
x
V
G
 
D
R
x
D
T
 
Y
G
 
T
I
 
V
E
 
T
I
 
I
G
 
G
N
 
D
N
 
N
V
 
V
-
x
L
-
 
I
-
 
A
-
 
P
N
 
N
I
 
V
S
 
T
F
 
L
Q
 
S
C
 
V
C
 
T
L
 
G
L
x
H
S
 
P
L
 
V
H
 
H
H
 
H
D
 
E
H
 
L
N
 
R
H
 
K
P
 
N
G
 
G
F
 
E
M
|
M
S
 
-
I
 
Y
G
 
S
G
 
F
I
 
P
V
 
I
T
 
T
I
 
I
H
 
G
D
 
N
H
 
N
A
 
V
W
|
W
L
 
I
G
|
G
A
x
S
R
 
H
A
 
V
I
 
V
I
 
I
L
 
N
P
 
P
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
D
G
 
N
A
 
S
V
 
V
V
 
I
A
x
G
A
|
A
G
 
G
A
 
S
V
 
I
V
 
V
T
 
T
K
 
K
D
 
D
V
 
I
P
 
P
D
 
P
F
 
N
T
 
V
V
 
V
V
 
A
G
 
A
G
 
G
V
 
V
P
|
P
A
 
C
K
 
R
I
 
V
I
 
I
G
x
R
Q
 
E
R
 
I
N
 
N

Sites not aligning to the query:

1krrA Galactoside acetyltransferase in complex with acetyl-coenzyme a (see paper)
34% identity, 54% coverage: 70:179/202 of query aligns to 73:185/200 of 1krrA

query
sites
1krrA
C
 
S
N
 
N
V
 
I
R
 
H
I
 
I
G
 
G
D
 
R
N
 
N
C
 
F
V
 
Y
L
 
A
N
|
N
R
 
F
E
 
N
I
 
L
Y
 
T
L
 
I
D
 
V
G
 
D
R
 
D
T
 
Y
G
 
T
I
 
V
E
 
T
I
 
I
G
 
G
N
 
D
N
 
N
V
 
V
-
 
L
-
x
I
-
x
A
-
x
P
N
 
N
I
 
V
S
 
T
F
 
L
Q
 
S
C
 
V
C
x
T
L
 
G
L
x
H
S
 
P
L
 
V
H
 
H
H
 
H
D
 
E
H
 
L
N
 
R
H
 
K
P
 
N
G
 
G
F
 
E
M
 
M
S
 
-
I
 
Y
G
 
S
G
 
F
I
 
P
V
 
I
T
 
T
I
 
I
H
 
G
D
 
N
H
 
N
A
 
V
W
 
W
L
 
I
G
|
G
A
x
S
R
 
H
A
 
V
I
 
V
I
 
I
L
x
N
P
 
P
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
D
G
 
N
A
 
S
V
 
V
V
 
I
A
x
G
A
|
A
G
 
G
A
 
S
V
 
I
V
 
V
T
 
T
K
 
K
D
 
D
V
 
I
P
 
P
D
 
P
F
 
N
T
 
V
V
 
V
V
 
A
G
x
A
G
 
G
V
 
V
P
|
P
A
 
C
K
 
R
I
 
V
I
 
I
G
x
R
Q
 
E
R
 
I
N
 
N

P07464 Galactoside O-acetyltransferase; GAT; Acetyl-CoA:galactoside 6-O-acetyltransferase; Thiogalactoside acetyltransferase; Thiogalactoside transacetylase; EC 2.3.1.18 from Escherichia coli (strain K12) (see 3 papers)
34% identity, 54% coverage: 70:179/202 of query aligns to 74:186/203 of P07464

query
sites
P07464
C
 
S
N
 
N
V
 
I
R
 
H
I
 
I
G
 
G
D
 
R
N
 
N
C
 
F
V
 
Y
L
 
A
N
|
N
R
 
F
E
 
N
I
 
L
Y
 
T
L
 
I
D
 
V
G
 
D
R
x
D
T
 
Y
G
 
T
I
 
V
E
 
T
I
 
I
G
 
G
N
 
D
N
 
N
V
 
V
-
 
L
-
 
I
-
 
A
-
 
P
N
 
N
I
 
V
S
 
T
F
 
L
Q
 
S
C
 
V
C
 
T
L
 
G
L
x
H
S
 
P
L
 
V
H
 
H
H
 
H
D
 
E
H
 
L
N
 
R
H
 
K
P
 
N
G
 
G
F
 
E
M
 
M
S
 
-
I
 
Y
G
 
S
G
 
F
I
 
P
V
 
I
T
 
T
I
 
I
H
 
G
D
 
N
H
 
N
A
 
V
W
 
W
L
 
I
G
 
G
A
x
S
R
 
H
A
 
V
I
 
V
I
 
I
L
 
N
P
 
P
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
D
G
 
N
A
 
S
V
 
V
V
 
I
A
 
G
A
|
A
G
 
G
A
 
S
V
 
I
V
 
V
T
|
T
K
|
K
D
 
D
V
 
I
P
 
P
D
 
P
F
 
N
T
 
V
V
 
V
V
 
A
G
 
A
G
 
G
V
 
V
P
 
P
A
 
C
K
x
R
I
 
V
I
 
I
G
x
R
Q
 
E
R
 
I
N
 
N

Sites not aligning to the query:

3nz2J Crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor
36% identity, 51% coverage: 72:175/202 of query aligns to 75:181/185 of 3nz2J

query
sites
3nz2J
V
 
I
R
 
R
I
 
I
G
 
G
D
 
D
N
 
H
C
 
T
V
 
F
L
 
I
N
 
N
R
 
M
E
 
N
I
 
V
Y
 
V
L
 
M
D
 
L
G
 
D
R
 
G
T
 
A
G
 
P
I
 
I
E
 
T
I
 
I
G
 
G
N
 
D
N
 
H
V
 
V
N
 
L
I
 
I
S
x
G
F
 
P
Q
 
S
C
 
T
C
 
Q
L
 
F
L
x
Y
S
 
T
L
 
A
H
 
S
H
|
H
D
 
S
H
 
L
N
 
D
H
 
Y
-
 
R
-
 
R
-
 
R
P
 
Q
G
 
A
F
 
W
M
 
E
S
 
T
I
 
I
G
 
C
G
 
K
I
 
P
V
 
I
T
 
V
I
 
I
H
 
E
D
 
D
H
 
D
A
 
V
W
|
W
L
 
I
G
|
G
A
 
G
R
 
N
A
 
V
I
 
V
I
 
I
L
 
N
P
 
Q
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
A
G
 
R
A
 
S
V
 
V
V
 
V
A
|
A
A
|
A
G
 
N
A
 
S
V
 
V
V
 
V
T
x
N
K
 
Q
D
 
D
V
 
V
P
 
P
D
 
P
F
 
D
T
 
T
V
 
L
V
 
V
G
|
G
G
 
G
V
x
T
P
|
P
A
 
A
K
 
R
I
 
I
I
 
L

Sites not aligning to the query:

3nz2C Crystal structure of hexapeptide-repeat containing-acetyltransferase vca0836 complexed with acetyl co enzyme a from vibrio cholerae o1 biovar eltor
36% identity, 51% coverage: 72:175/202 of query aligns to 72:178/183 of 3nz2C

query
sites
3nz2C
V
 
I
R
 
R
I
 
I
G
 
G
D
 
D
N
 
H
C
 
T
V
 
F
L
 
I
N
 
N
R
 
M
E
 
N
I
 
V
Y
 
V
L
 
M
D
 
L
G
 
D
R
 
G
T
 
A
G
 
P
I
 
I
E
 
T
I
 
I
G
 
G
N
 
D
N
 
H
V
 
V
N
 
L
I
 
I
S
 
G
F
 
P
Q
 
S
C
 
T
C
 
Q
L
 
F
L
x
Y
S
 
T
L
 
A
H
 
S
H
|
H
D
 
S
H
 
L
N
 
D
H
 
Y
-
 
R
-
 
R
-
 
R
P
 
Q
G
 
A
F
 
W
M
 
E
S
 
T
I
 
I
G
 
C
G
 
K
I
 
P
V
 
I
T
 
V
I
 
I
H
 
E
D
 
D
H
 
D
A
 
V
W
 
W
L
 
I
G
|
G
A
 
G
R
 
N
A
 
V
I
 
V
I
 
I
L
 
N
P
 
Q
G
 
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
A
G
 
R
A
 
S
V
 
V
V
 
V
A
|
A
A
|
A
G
x
N
A
 
S
V
 
V
V
 
V
T
x
N
K
 
Q
D
 
D
V
 
V
P
 
P
D
 
P
F
 
D
T
 
T
V
 
L
V
 
V
G
|
G
G
 
G
V
x
T
P
|
P
A
 
A
K
 
R
I
 
I
I
x
L

Sites not aligning to the query:

3ectA Crystal structure of the hexapeptide-repeat containing- acetyltransferase vca0836 from vibrio cholerae
36% identity, 51% coverage: 72:175/202 of query aligns to 65:171/176 of 3ectA

query
sites
3ectA
V
 
I
R
 
R
I
 
I
G
 
G
D
 
D
N
 
H
C
 
T
V
 
F
L
 
I
N
 
N
R
 
M
E
 
N
I
 
V
Y
 
V
L
 
M
D
 
L
G
 
D
R
 
G
T
 
A
G
 
P
I
 
I
E
 
T
I
 
I
G
 
G
N
 
D
N
 
H
V
 
V
N
 
L
I
 
I
S
 
G
F
 
P
Q
 
S
C
 
T
C
 
Q
L
 
F
L
 
Y
S
 
T
L
 
A
H
 
S
H
 
H
D
 
S
H
 
L
N
 
D
H
 
Y
-
 
R
-
 
R
-
 
R
P
 
Q
G
 
A
F
 
W
M
 
E
S
 
T
I
 
I
G
 
C
G
 
K
I
 
P
V
 
I
T
 
V
I
 
I
H
 
E
D
 
D
H
 
D
A
 
V
W
 
W
L
 
I
G
 
G
A
 
G
R
 
N
A
 
V
I
 
V
I
 
I
L
 
N
P
 
Q
G
|
G
V
 
V
T
 
T
I
 
I
G
 
G
K
 
A
G
 
R
A
 
S
V
 
V
V
 
V
A
 
A
A
 
A
G
 
N
A
 
S
V
 
V
V
 
V
T
 
N
K
 
Q
D
|
D
V
 
V
P
 
P
D
 
P
F
 
D
T
 
T
V
 
L
V
 
V
G
 
G
G
 
G
V
 
T
P
 
P
A
 
A
K
 
R
I
 
I
I
 
L

A1ADJ6 Polysialic acid O-acetyltransferase; Capsule O-acetyl transferase; EC 2.3.1.136 from Escherichia coli O1:K1 / APEC (see paper)
31% identity, 65% coverage: 49:179/202 of query aligns to 169:280/307 of A1ADJ6

query
sites
A1ADJ6
V
 
V
L
 
I
I
 
I
G
 
G
Q
 
R
R
 
R
T
 
T
H
 
T
V
 
I
S
 
G
M
 
A
R
 
-
Q
 
-
F
 
G
F
 
F
T
 
E
G
 
V
Y
 
V
H
 
T
T
 
D
R
 
K
C
 
C
N
 
N
V
 
V
R
 
T
I
 
I
G
 
G
D
 
H
N
 
D
C
 
C
V
 
M
L
 
I
N
 
A
R
 
R
E
 
D
I
 
V
Y
 
I
L
 
L
D
 
R
G
 
A
R
 
S
T
 
D
G
 
G
I
x
H
E
 
P
I
 
I
G
 
-
N
 
-
N
 
-
V
 
-
N
 
-
I
 
-
S
 
-
F
 
-
Q
 
-
C
 
-
C
 
-
L
 
-
L
 
-
S
 
-
L
 
-
H
 
-
H
 
F
D
 
D
H
 
I
N
 
H
H
 
S
P
 
K
G
 
K
F
 
R
M
 
I
S
 
N
I
 
W
G
 
A
G
 
K
I
 
D
V
 
I
T
 
I
I
 
I
H
 
S
D
 
S
H
 
Y
A
 
V
W
|
W
L
 
V
G
 
G
A
 
R
R
 
N
A
 
V
I
 
S
I
 
I
L
 
M
P
 
K
G
 
G
V
 
V
T
 
S
I
 
V
G
 
G
K
 
S
G
 
G
A
 
S
V
 
V
V
 
I
A
 
G
A
 
Y
G
 
G
A
 
S
V
 
I
V
 
V
T
 
T
K
 
K
D
 
D
V
 
V
P
 
P
D
 
S
F
 
M
T
 
C
V
 
A
V
 
A
G
 
A
G
 
G
V
 
N
P
 
P
A
 
A
K
 
K
I
 
I
I
 
I
G
 
-
Q
 
K
R
 
R
N
 
N

6pubA Crystal structure of the type b chloramphenicol acetyltransferase from vibrio cholerae in the complex with crystal violet
50% identity, 33% coverage: 117:182/202 of query aligns to 105:169/210 of 6pubA

query
sites
6pubA
G
 
G
F
 
F
M
 
T
S
 
R
I
 
S
G
 
G
G
 
D
I
 
T
V
 
I
T
 
I
I
 
G
H
 
H
D
 
D
H
 
-
A
 
V
W
 
W
L
 
I
G
 
G
A
 
T
R
 
E
A
 
A
I
 
M
I
 
I
L
 
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
H
G
 
G
A
 
A
V
 
I
V
 
I
A
 
A
A
 
S
G
 
R
A
 
S
V
 
V
V
 
V
T
 
T
K
 
K
D
 
D
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
E
V
 
V
V
 
V
G
 
G
G
 
S
V
 
N
P
 
P
A
 
A
K
 
K
I
 
H
I
 
I
G
 
K
Q
 
F
R
 
R
N
 
F
P
 
S
D
 
D
V
 
V

Sites not aligning to the query:

6u9cA The 2.2 a crystal structure of the type b chloramphenicol acetyltransferase from vibrio cholerae in the complex with acetyl coa
50% identity, 33% coverage: 117:182/202 of query aligns to 102:166/206 of 6u9cA

query
sites
6u9cA
G
 
G
F
 
F
M
 
T
S
 
R
I
 
S
G
 
G
G
 
D
I
 
T
V
 
I
T
 
I
I
 
G
H
 
H
D
 
D
H
 
-
A
 
V
W
|
W
L
 
I
G
 
G
A
 
T
R
 
E
A
 
A
I
 
M
I
 
I
L
 
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
H
G
 
G
A
 
A
V
 
I
V
 
I
A
|
A
A
 
S
G
 
R
A
 
S
V
 
V
V
 
V
T
 
T
K
 
K
D
 
D
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
E
V
 
V
V
 
V
G
 
G
G
 
S
V
 
N
P
 
P
A
 
A
K
 
K
I
 
H
I
|
I
G
 
K
Q
 
F
R
 
R
N
 
F
P
 
S
D
 
D
V
 
V

8j40A Crystal structure of catb8 in complex with chloramphenicol (see paper)
43% identity, 30% coverage: 122:181/202 of query aligns to 107:166/209 of 8j40A

query
sites
8j40A
G
 
A
G
 
G
I
 
D
V
 
T
T
 
V
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
|
W
L
 
I
G
 
G
A
 
S
R
 
E
A
 
A
I
 
M
I
 
I
L
 
M
P
 
P
G
 
G
V
 
I
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
|
V
V
 
I
A
 
G
A
x
S
G
 
R
A
 
S
V
 
L
V
 
V
T
 
T
K
 
K
D
 
D
V
 
V
P
 
E
D
 
P
F
 
Y
T
 
A
V
 
I
V
 
I
G
 
G
G
 
G
V
 
N
P
 
P
A
 
A
K
 
K
I
 
Q
I
 
I
G
 
K
Q
 
K
R
 
R
N
 
F
P
 
S
D
 
D

Sites not aligning to the query:

4hurA Crystal structure of streptogramin group a antibiotic acetyltransferase vata from staphylococcus aureus in complex with acetyl coenzyme a (see paper)
44% identity, 31% coverage: 119:181/202 of query aligns to 107:169/211 of 4hurA

query
sites
4hurA
M
 
L
S
 
P
I
 
L
G
x
K
G
 
G
I
 
D
V
 
I
T
 
E
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
|
W
L
x
I
G
|
G
A
x
R
R
 
D
A
 
V
I
 
T
I
 
I
L
x
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
 
I
V
 
I
A
|
A
A
|
A
G
 
E
A
 
A
V
 
V
V
 
V
T
|
T
K
 
K
D
 
N
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
S
V
 
I
V
 
V
G
|
G
G
 
G
V
 
N
P
|
P
A
 
L
K
 
K
I
 
F
I
|
I
G
x
R
Q
 
K
R
 
R
N
 
F
P
 
S
D
 
D

Sites not aligning to the query:

6x3cA Crystal structure of streptogramin a acetyltransferase vata from staphylococcus aureus in complex with streptogramin analog f1037 (47) (see paper)
44% identity, 31% coverage: 119:181/202 of query aligns to 107:169/207 of 6x3cA

query
sites
6x3cA
M
 
L
S
 
P
I
 
L
G
 
K
G
 
G
I
 
D
V
 
I
T
 
E
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
|
W
L
 
I
G
|
G
A
x
R
R
 
D
A
 
V
I
 
T
I
 
I
L
x
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
 
I
V
 
I
A
|
A
A
|
A
G
 
E
A
 
A
V
 
V
V
 
V
T
 
T
K
 
K
D
 
N
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
S
V
 
I
V
 
V
G
 
G
G
 
G
V
 
N
P
 
P
A
 
L
K
 
K
I
 
F
I
 
I
G
 
R
Q
 
K
R
 
R
N
 
F
P
 
S
D
 
D

Sites not aligning to the query:

4husA Crystal structure of streptogramin group a antibiotic acetyltransferase vata from staphylococcus aureus in complex with virginiamycin m1 (see paper)
44% identity, 31% coverage: 119:181/202 of query aligns to 107:169/212 of 4husA

query
sites
4husA
M
 
L
S
 
P
I
 
L
G
 
K
G
 
G
I
 
D
V
 
I
T
 
E
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
 
W
L
 
I
G
 
G
A
 
R
R
 
D
A
 
V
I
 
T
I
 
I
L
 
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
 
I
V
 
I
A
 
A
A
 
A
G
 
E
A
 
A
V
 
V
V
 
V
T
 
T
K
 
K
D
 
N
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
S
V
 
I
V
 
V
G
 
G
G
 
G
V
 
N
P
 
P
A
 
L
K
 
K
I
 
F
I
 
I
G
 
R
Q
 
K
R
 
R
N
 
F
P
 
S
D
 
D

Sites not aligning to the query:

6x3jA Crystal structure of streptogramin a acetyltransferase vata from staphylococcus aureus in complex with streptogramin analog f0224 (46) (see paper)
44% identity, 31% coverage: 119:181/202 of query aligns to 107:169/206 of 6x3jA

query
sites
6x3jA
M
x
L
S
 
P
I
 
L
G
 
K
G
 
G
I
 
D
V
 
I
T
 
E
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
|
W
L
 
I
G
|
G
A
 
R
R
 
D
A
 
V
I
 
T
I
 
I
L
 
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
 
I
V
 
I
A
 
A
A
 
A
G
 
E
A
 
A
V
 
V
V
 
V
T
 
T
K
 
K
D
 
N
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
S
V
 
I
V
 
V
G
 
G
G
 
G
V
 
N
P
 
P
A
 
L
K
 
K
I
 
F
I
 
I
G
 
R
Q
 
K
R
 
R
N
 
F
P
 
S
D
 
D

Sites not aligning to the query:

6x3cE Crystal structure of streptogramin a acetyltransferase vata from staphylococcus aureus in complex with streptogramin analog f1037 (47) (see paper)
44% identity, 31% coverage: 119:181/202 of query aligns to 107:169/203 of 6x3cE

query
sites
6x3cE
M
 
L
S
 
P
I
 
L
G
 
K
G
 
G
I
 
D
V
 
I
T
 
E
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
|
W
L
 
I
G
|
G
A
 
R
R
 
D
A
 
V
I
 
T
I
 
I
L
 
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
 
I
V
 
I
A
|
A
A
|
A
G
 
E
A
 
A
V
 
V
V
 
V
T
 
T
K
 
K
D
 
N
V
 
V
P
 
A
D
 
P
F
 
Y
T
 
S
V
 
I
V
 
V
G
 
G
G
 
G
V
x
N
P
|
P
A
 
L
K
 
K
I
 
F
I
 
I
G
 
R
Q
 
K
R
 
R
N
 
F
P
 
S
D
 
D

Sites not aligning to the query:

1mrlA Crystal structure of streptogramin a acetyltransferase with dalfopristin (see paper)
45% identity, 30% coverage: 119:178/202 of query aligns to 108:167/204 of 1mrlA

query
sites
1mrlA
M
x
L
S
 
P
I
 
I
G
 
K
G
 
G
I
 
D
V
 
T
T
 
I
I
 
I
H
 
G
D
 
N
H
 
D
A
 
V
W
 
W
L
 
I
G
 
G
A
 
K
R
 
D
A
 
V
I
 
V
I
 
I
L
 
M
P
 
P
G
 
G
V
 
V
T
 
K
I
 
I
G
 
G
K
 
D
G
 
G
A
 
A
V
 
I
V
 
V
A
 
A
A
 
A
G
 
N
A
 
S
V
 
V
V
 
V
T
 
V
K
 
K
D
 
D
V
 
I
P
 
A
D
 
P
F
 
Y
T
 
M
V
 
L
V
 
A
G
 
G
G
 
G
V
 
N
P
 
P
A
 
A
K
 
N
I
 
E
I
 
I
G
 
K
Q
 
Q
R
 
R

Sites not aligning to the query:

Query Sequence

>WP_011883536.1 NCBI__GCF_000016205.1:WP_011883536.1
MKSRIKARLLASSTYFFLAALKYYIGNNFIARMPIERVRNFYYRRVLGVLIGQRTHVSMR
QFFTGYHTRCNVRIGDNCVLNREIYLDGRTGIEIGNNVNISFQCCLLSLHHDHNHPGFMS
IGGIVTIHDHAWLGARAIILPGVTIGKGAVVAAGAVVTKDVPDFTVVGGVPAKIIGQRNP
DVAYLTDFSPFFDTDVFDESRG

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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory