Comparing WP_011950992.1 NCBI__GCF_000016765.1:WP_011950992.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
26% identity, 90% coverage: 45:463/468 of query aligns to 56:487/503 of Q8C165
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
23% identity, 92% coverage: 34:462/468 of query aligns to 6:398/408 of Q03154
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
28% identity, 80% coverage: 43:418/468 of query aligns to 13:335/383 of 7uoiA
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
29% identity, 47% coverage: 40:257/468 of query aligns to 6:214/381 of 8uw6B
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
29% identity, 53% coverage: 39:286/468 of query aligns to 4:239/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
29% identity, 53% coverage: 39:286/468 of query aligns to 4:239/375 of 4pqaA
Sites not aligning to the query:
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
25% identity, 77% coverage: 104:462/468 of query aligns to 75:397/407 of P37111
Sites not aligning to the query:
1lfwA Crystal structure of pepv (see paper)
35% identity, 26% coverage: 55:177/468 of query aligns to 42:155/468 of 1lfwA
Sites not aligning to the query:
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
35% identity, 26% coverage: 55:177/468 of query aligns to 42:155/470 of P45494
Sites not aligning to the query:
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
33% identity, 31% coverage: 64:210/468 of query aligns to 27:188/265 of 4op4B
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
23% identity, 92% coverage: 35:463/468 of query aligns to 20:454/458 of 2pokA
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
33% identity, 21% coverage: 99:196/468 of query aligns to 94:193/426 of 3pfoA
Sites not aligning to the query:
1q7lA Zn-binding domain of the t347g mutant of human aminoacylase-i (see paper)
38% identity, 16% coverage: 104:176/468 of query aligns to 69:142/192 of 1q7lA
Sites not aligning to the query:
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
29% identity, 45% coverage: 62:273/468 of query aligns to 29:238/377 of 7t1qA
Sites not aligning to the query:
Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human)
31% identity, 28% coverage: 46:177/468 of query aligns to 24:168/475 of Q96KP4
Sites not aligning to the query:
7lgpB Dape enzyme from shigella flexneri
26% identity, 40% coverage: 95:283/468 of query aligns to 54:237/377 of 7lgpB
P06621 Carboxypeptidase G2; CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase; EC 3.4.17.11 from Pseudomonas sp. (strain RS-16) (see paper)
32% identity, 36% coverage: 7:176/468 of query aligns to 14:176/415 of P06621
Sites not aligning to the query:
P15288 Cytosol non-specific dipeptidase; Aminoacyl-histidine dipeptidase; Beta-alanyl-histidine dipeptidase; Carnosinase; Cysteinylglycinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase; EC 3.4.13.18 from Escherichia coli (strain K12) (see 2 papers)
29% identity, 21% coverage: 40:138/468 of query aligns to 12:109/485 of P15288
Sites not aligning to the query:
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
25% identity, 45% coverage: 46:256/468 of query aligns to 28:257/478 of 2zogA
Sites not aligning to the query:
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
25% identity, 45% coverage: 46:256/468 of query aligns to 28:257/478 of 2zofA
Sites not aligning to the query:
>WP_011950992.1 NCBI__GCF_000016765.1:WP_011950992.1
MRRSRTLPIALLAGAILPLAAQPVHGAAPTPVDPAQHGQMLDIWKKMIAIPTVHGRGQTR
AMADYIAGLLKQGGFAAEDIVIEGDGDDISLAARYRGTGKGKPILLSGHMDVVEARPSDW
TRDPFVPVEENGFVYGRGALDMKFGDAVLVSTLLKLKAEGFKPSRDILLLLSGDEETAMA
TTARLAERYGGDAELLLNADGGGGMLDDQGKPVAFYVQGGEKTYADIEISVTDPGGHSSR
PGATNAIATLAQAIDRIAAYKFPAQVNEITRAYFKATGKQVGGTIGAAMLRFADDPNDAA
AVATLRAEPEYVGITGTTCVPTMLSGGHALNALPQKATVSVNCRIFPGVPIDSVRDTLAK
VIDNPKATVTILDHPLGSDASPLRPDLMKAVRKGIDQSFPGLPIVPQMAAGATDSLYFRA
KGVPSYGVLGMFLNPADDFSHGLNERAPVASIDPALRLMRTLIVDLSK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory