Comparing WP_011970457.1 NCBI__GCF_000017145.1:WP_011970457.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
32% identity, 94% coverage: 21:371/374 of query aligns to 30:377/381 of 8uw6B
Sites not aligning to the query:
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
30% identity, 95% coverage: 6:359/374 of query aligns to 13:368/383 of 7uoiA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
30% identity, 75% coverage: 47:328/374 of query aligns to 46:330/377 of 7t1qA
Sites not aligning to the query:
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
29% identity, 91% coverage: 20:361/374 of query aligns to 24:367/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
29% identity, 91% coverage: 20:361/374 of query aligns to 20:363/377 of P44514
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
30% identity, 91% coverage: 28:369/374 of query aligns to 33:359/366 of Q8P8J5
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
28% identity, 100% coverage: 1:374/374 of query aligns to 3:376/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
27% identity, 99% coverage: 2:373/374 of query aligns to 4:375/375 of 4pqaA
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
29% identity, 91% coverage: 28:369/374 of query aligns to 34:354/360 of 2f7vA
7lgpB Dape enzyme from shigella flexneri
27% identity, 87% coverage: 48:374/374 of query aligns to 49:377/377 of 7lgpB
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
29% identity, 53% coverage: 65:262/374 of query aligns to 76:282/408 of Q03154
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
26% identity, 94% coverage: 6:358/374 of query aligns to 24:406/426 of 3pfoA
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
23% identity, 82% coverage: 35:340/374 of query aligns to 58:363/407 of P37111
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
31% identity, 51% coverage: 20:208/374 of query aligns to 22:204/258 of 4h2kA
Sites not aligning to the query:
3dljA Crystal structure of human carnosine dipeptidase 1
35% identity, 25% coverage: 52:146/374 of query aligns to 83:181/471 of 3dljA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
35% identity, 25% coverage: 52:146/374 of query aligns to 114:212/507 of Q96KN2
Sites not aligning to the query:
Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 2 papers)
40% identity, 21% coverage: 66:144/374 of query aligns to 96:177/475 of Q9D1A2
Sites not aligning to the query:
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
40% identity, 21% coverage: 66:144/374 of query aligns to 100:181/478 of 2zogA
Sites not aligning to the query:
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
40% identity, 21% coverage: 66:144/374 of query aligns to 100:181/478 of 2zofA
Sites not aligning to the query:
5xoyA Crystal structure of lysk from thermus thermophilus in complex with lysine (see paper)
33% identity, 43% coverage: 65:223/374 of query aligns to 58:200/341 of 5xoyA
Sites not aligning to the query:
>WP_011970457.1 NCBI__GCF_000017145.1:WP_011970457.1
MQAAEILGKLVGFRSVVGLPNDDAVSWIRGYLECHGIAVDVLPGPEGDRSNIFATIGPKE
AHGYILSGHMDVVPATEAGWTSDPFILRAEGGRLYGRGTTDMKGFLAAGLAAVPKLAAMP
LRRPLHLAFSYDEEAGCRGVPHMIARMPELCRQPLGAIIGEPSGMRAIRAHKGKAAARLT
VRGRSGHSSRPDQGLNAIHGVAGVLTQAVAEAVRLAGGPFEHVFEPPYSSLQIGTVKGGQ
AVNIIPDSCEVELEARAISGVDPAELLTPVRKIAEALTALGFEVEWQELSAYPALSLEPH
APLAALLEALTGREPLPAVSYGTEAGLFQRAGIDAIICGPGDIGRAHKADEYILIDELMA
CQAMIEALGAHCIA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory