Comparing WP_011974176.1 NCBI__GCF_000017185.1:WP_011974176.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
6n2oC 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
37% identity, 96% coverage: 15:377/377 of query aligns to 202:567/572 of 6n2oC
Sites not aligning to the query:
6n2oA 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
37% identity, 96% coverage: 15:377/377 of query aligns to 202:567/572 of 6n2oA
Sites not aligning to the query:
6n2nA Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
37% identity, 96% coverage: 15:377/377 of query aligns to 202:567/572 of 6n2nA
5b47A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - pyruvate complex (see paper)
30% identity, 95% coverage: 15:374/377 of query aligns to 232:607/627 of 5b47A
5b46A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand free form (see paper)
30% identity, 95% coverage: 15:374/377 of query aligns to 232:607/627 of 5b46A
Q96XT2 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
30% identity, 95% coverage: 15:374/377 of query aligns to 233:608/628 of Q96XT2
Q96Y66 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
30% identity, 88% coverage: 8:340/377 of query aligns to 220:573/627 of Q96Y66
Sites not aligning to the query:
P72578 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Sulfolobus sp. (see 2 papers)
30% identity, 88% coverage: 8:340/377 of query aligns to 220:573/632 of P72578
5b48A 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai (see paper)
30% identity, 87% coverage: 13:340/377 of query aligns to 198:525/576 of 5b48A
9bt4A Pyruvate:ferredoxin oxidoreductase from methanosarcina acetivorans (see paper)
25% identity, 98% coverage: 9:376/377 of query aligns to 7:379/402 of 9bt4A
6cioA Pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with lactyl-tpp bound (see paper)
23% identity, 79% coverage: 36:334/377 of query aligns to 25:321/1164 of 6cioA
Sites not aligning to the query:
6cipA Pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with acetyl-tpp bound (see paper)
23% identity, 79% coverage: 36:334/377 of query aligns to 25:321/1165 of 6cipA
Sites not aligning to the query:
6ciqA Pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with coenzyme a bound (see paper)
23% identity, 79% coverage: 36:334/377 of query aligns to 25:321/1169 of 6ciqA
Sites not aligning to the query:
6cinB Crystal structure of pyruvate:ferredoxin oxidoreductase from moorella thermoacetica (see paper)
23% identity, 79% coverage: 36:334/377 of query aligns to 25:321/1169 of 6cinB
Sites not aligning to the query:
Q2RMD6 Pyruvate:ferredoxin oxidoreductase; PFOR; Pyruvate synthase; EC 1.2.7.1 from Moorella thermoacetica (strain ATCC 39073 / JCM 9320) (see paper)
23% identity, 79% coverage: 36:334/377 of query aligns to 26:322/1171 of Q2RMD6
Sites not aligning to the query:
>WP_011974176.1 NCBI__GCF_000017185.1:WP_011974176.1
MIGKDGKLKPGTYFMQGNEACAEGALSAGCNFFGGYPITPSSEVAERLSKRLPQIGRPYV
QMEDEISALATVLGASWAGAKAMTATSGPGFSLMQEHIGYGVMTETPFVLVDVQRGSPST
GQPTMASQSDMMQAKWGSHGDYQIIAFAPSSVQECFEYTIKAFNMSEKYRVPAFVMSDEI
VGHMREKLVIPEEIEIINRKEGLGKYPFYPEEDLIPKMPTFGNGWNTHVTGLTHSEKGYP
DAASKPAEHHKLVKRLNDKILNNLKDIVSYEEKYLDDCGDVVVVSYGAPSRSAETAVNEL
REKGVSAGILRLETVWPFPDYKILEIAKKTEKIIIPEMNFGQISREVQRASKGHCEVSLV
GKTGGEIHVPEEIINEL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory