Comparing WP_011988773.1 NCBI__GCF_000016505.1:WP_011988773.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate (see paper)
43% identity, 97% coverage: 4:208/211 of query aligns to 4:207/207 of 1h2fA
Sites not aligning to the query:
1h2eA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
43% identity, 97% coverage: 4:208/211 of query aligns to 4:207/207 of 1h2eA
4ij6A Crystal structure of a novel-type phosphoserine phosphatase mutant (h9a) from hydrogenobacter thermophilus tk-6 in complex with l-phosphoserine (see paper)
35% identity, 97% coverage: 1:205/211 of query aligns to 1:203/207 of 4ij6A
6m1xC Crystal structure of phosphoserine phosphatase in complex with 3- phosphoglyceric acid from entamoeba histolytica (see paper)
35% identity, 79% coverage: 1:166/211 of query aligns to 1:162/196 of 6m1xC
5zr2C Crystal structure of phosphoserine phosphatase mutant (h9a) from entamoeba histolytica in complex with phosphoserine (see paper)
34% identity, 79% coverage: 1:166/211 of query aligns to 1:162/198 of 5zr2C
P36623 Phosphoglycerate mutase; PGAM; BPG-dependent PGAM; MPGM; Phosphoglyceromutase; EC 5.4.2.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 79% coverage: 4:170/211 of query aligns to 10:182/211 of P36623
Q9HIJ2 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) (see paper)
31% identity, 87% coverage: 6:189/211 of query aligns to 6:179/200 of Q9HIJ2
1tipA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase (see paper)
28% identity, 81% coverage: 1:170/211 of query aligns to 1:162/191 of 1tipA
1c81A Michaelis complex of fructose-2,6-bisphosphatase
28% identity, 81% coverage: 1:170/211 of query aligns to 1:162/191 of 1c81A
1c80A Regulatory complex of fructose-2,6-bisphosphatase
28% identity, 81% coverage: 1:170/211 of query aligns to 1:162/191 of 1c80A
1c7zA Regulatory complex of fructose-2,6-bisphosphatase
28% identity, 81% coverage: 1:170/211 of query aligns to 1:162/191 of 1c7zA
1fbtA The bisphosphatase domain of the bifunctional rat liver 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase (see paper)
28% identity, 79% coverage: 4:170/211 of query aligns to 3:161/190 of 1fbtA
P07953 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Rattus norvegicus (Rat) (see 3 papers)
28% identity, 79% coverage: 4:170/211 of query aligns to 254:412/471 of P07953
Sites not aligning to the query:
Q7ZVE3 Fructose-2,6-bisphosphatase TIGAR B; TP53-induced glycolysis and apoptosis regulator B; EC 3.1.3.46 from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
28% identity, 65% coverage: 4:140/211 of query aligns to 6:142/257 of Q7ZVE3
P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme; EC 2.7.1.105; EC 3.1.3.46 from Homo sapiens (Human) (see paper)
28% identity, 79% coverage: 4:170/211 of query aligns to 254:412/471 of P16118
Sites not aligning to the query:
1k6mA Crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (see paper)
27% identity, 79% coverage: 4:170/211 of query aligns to 215:373/432 of 1k6mA
Sites not aligning to the query:
3gp5A Crystal structure of phosphoglyceromutase from burkholderia pseudomallei with 3-phosphoglyceric acid and vanadate (see paper)
30% identity, 78% coverage: 1:164/211 of query aligns to 1:195/248 of 3gp5A
Q3JWH7 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM; EC 5.4.2.11 from Burkholderia pseudomallei (strain 1710b) (see paper)
30% identity, 78% coverage: 1:164/211 of query aligns to 1:195/249 of Q3JWH7
3gp3A Crystal structure of phosphoglyceromutase from burkholderia pseudomallei with 2-phosphoserine (see paper)
30% identity, 78% coverage: 1:164/211 of query aligns to 1:195/229 of 3gp3A
3fdzA Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b with bound 2,3-diphosphoglyceric acid and 3- phosphoglyceric acid (see paper)
30% identity, 78% coverage: 1:164/211 of query aligns to 1:195/230 of 3fdzA
>WP_011988773.1 NCBI__GCF_000016505.1:WP_011988773.1
MVKLYLVRHGETIWNIERKMQGGMKDSPLTKKGIEQANLLKNRMENINFDIIYSSPLERA
VKTSRIVAAQRNIPIIKDDRLMEIDIGEWGGLTKEQARERNPEQLNNFWTNPKIYVPDTG
ESFAQVKTRVVSLIKEIISKYEGKSILIVTHTVILRIMMAYFENRPLDELWEGSYIHQAS
LSEVEIENGCYNILLYGDTSHLGEIKSVNTI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory