Comparing WP_012113865.1 NCBI__GCF_000017645.1:WP_012113865.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3jtxB Crystal structure of aminotransferase (np_283882.1) from neisseria meningitidis z2491 at 1.91 a resolution
35% identity, 94% coverage: 25:413/416 of query aligns to 12:390/393 of 3jtxB
6l1nA Substrate bound bacf structure from bacillus subtillis (see paper)
26% identity, 94% coverage: 23:411/416 of query aligns to 14:383/393 of 6l1nA
6l1oB Product bound bacf structure from bacillus subtillis (see paper)
26% identity, 90% coverage: 39:411/416 of query aligns to 31:384/392 of 6l1oB
Sites not aligning to the query:
6l1lB Apo-bacf structure from bacillus subtillis (see paper)
26% identity, 90% coverage: 39:411/416 of query aligns to 31:384/393 of 6l1lB
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
25% identity, 83% coverage: 68:411/416 of query aligns to 64:391/402 of P14909
Sites not aligning to the query:
1o4sB Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
24% identity, 91% coverage: 34:411/416 of query aligns to 31:378/384 of 1o4sB
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
23% identity, 93% coverage: 24:411/416 of query aligns to 12:378/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
23% identity, 93% coverage: 24:411/416 of query aligns to 12:378/388 of 1gd9A
2x5dD Crystal structure of a probable aminotransferase from pseudomonas aeruginosa (see paper)
26% identity, 67% coverage: 72:351/416 of query aligns to 51:324/380 of 2x5dD
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v (see paper)
26% identity, 78% coverage: 24:347/416 of query aligns to 13:331/402 of 5wmiA
Sites not aligning to the query:
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate (see paper)
29% identity, 79% coverage: 48:375/416 of query aligns to 39:351/382 of 1bkgA
1bjwA Aspartate aminotransferase from thermus thermophilus (see paper)
29% identity, 79% coverage: 48:375/416 of query aligns to 39:351/382 of 1bjwA
Sites not aligning to the query:
Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
29% identity, 79% coverage: 48:375/416 of query aligns to 39:351/385 of Q56232
Sites not aligning to the query:
2o1bA Structure of aminotransferase from staphylococcus aureus
23% identity, 89% coverage: 43:412/416 of query aligns to 22:369/376 of 2o1bA
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
29% identity, 79% coverage: 48:375/416 of query aligns to 39:351/382 of 1b5oA
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
28% identity, 79% coverage: 48:375/416 of query aligns to 39:351/382 of 1gc4A
Sites not aligning to the query:
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan (see paper)
28% identity, 79% coverage: 48:375/416 of query aligns to 39:351/382 of 1gc3A
Sites not aligning to the query:
5wmhA Arabidopsis thaliana prephenate aminotransferase (see paper)
26% identity, 78% coverage: 24:347/416 of query aligns to 12:331/399 of 5wmhA
Q02635 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.79 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
23% identity, 77% coverage: 39:358/416 of query aligns to 30:342/400 of Q02635
Sites not aligning to the query:
6f77A Crystal structure of the prephenate aminotransferase from rhizobium meliloti (see paper)
23% identity, 77% coverage: 39:358/416 of query aligns to 29:341/399 of 6f77A
>WP_012113865.1 NCBI__GCF_000017645.1:WP_012113865.1
MIAARKDRSAVPASPVAPPEDRRSPFIRLADLLAGIDPGRQPLSAAVGEPQHAMPDFVGP
VLAQALPGFGRYPRAEGTPTFRAAAARWLAQRYALARPIDADREVLALNGSREGLFSAAI
VARRLTDPKKGAKGRPAMLLPNPFYAAYAAGAEAAGCEAVVVPTSRESGWLPDLDALDPA
LLERTVALYIASPANPQGSIASAAYLGRALELARRHGAFLFSDECYSEIYLGAEKPAGIL
EVAGGDFSRAVAFNSLSKRSSLPGLRCGFCAGDPAFLKDFLAFRWVAAPQVPEPLQAVAV
AALEDEAHVTISRDLYRAKFDLADRMLEGRLGYERPGGGFFLWLDVSHLASDTLSGGEAA
AVKLWREQGLRTVPGGYLARRDLTGANPAANFLRVALVQDLPTCEEVLTRLVAALT
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory