SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing WP_012115897.1 NCBI__GCF_000017645.1:WP_012115897.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

3al0C Crystal structure of the glutamine transamidosome from thermotoga maritima in the glutamylation state. (see paper)
29% identity, 96% coverage: 3:93/95 of query aligns to 2:92/564 of 3al0C

query
sites
3al0C

V

V

D

T

Q

K

A

D

T

L

V

V

R

L

R

H

V

L

A

E

H

N

L

L

A

A

R

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I

L

S

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R

S

E

E

D

D

E

Q

L

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G

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H

S

L

L

Q

M

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K

E

D

L

F

N

Q

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E

I

I

L

L

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D

F

Y

V

V

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E

Q

L

L

L

A

N

D

E

L

V

D

D

V

V

S

E

G

G

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V

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E

P

P

L

M

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Y

S

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P

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V

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S

L

A

P

K

M

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R

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K

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F

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F

H

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C

M

P

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L

K

A

K

N

N

A

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P

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G

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G

G

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I

Sites not aligning to the query:

active site: 110, 335
binding o5'-(l-glutamyl-sulfamoyl)-adenosine: 106, 108, 109, 118, 122, 142, 276, 294, 295, 297, 298, 324, 325, 333
binding : 144, 145, 148, 208, 213, 252, 255, 266, 269, 270, 276, 297, 298, 299, 300, 301, 304, 330, 332, 363, 364, 365, 370, 387, 389, 391, 392, 397, 400, 407, 446, 447, 453, 457, 509, 520, 524, 527, 535, 536, 538, 539

Query Sequence

>WP_012115897.1 NCBI__GCF_000017645.1:WP_012115897.1
MSVDQATVRRVAHLARISVREDELGHLQNELNAILEFVEQLADLDVSGVEPLTSVVPVEL
PMREDVVTDGHCPEKVLANAPDAEGGFFTVPKVVE

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory