Comparing WP_012168760.1 NCBI__GCF_000010525.1:WP_012168760.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 12 hits to proteins with known functional sites (download)
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
48% identity, 91% coverage: 32:398/403 of query aligns to 15:382/387 of Q6FEQ3
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
46% identity, 85% coverage: 37:380/403 of query aligns to 12:347/358 of P45131
Sites not aligning to the query:
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
42% identity, 74% coverage: 32:329/403 of query aligns to 83:377/504 of Q10341
Sites not aligning to the query:
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
39% identity, 90% coverage: 30:392/403 of query aligns to 3:346/346 of 5w8oB
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
42% identity, 83% coverage: 44:376/403 of query aligns to 23:358/374 of D2Z028
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
39% identity, 88% coverage: 39:393/403 of query aligns to 18:366/368 of 7rytB
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
39% identity, 88% coverage: 39:393/403 of query aligns to 18:366/367 of 8f2lA
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
39% identity, 87% coverage: 39:388/403 of query aligns to 19:362/366 of 6puxA
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
39% identity, 90% coverage: 30:393/403 of query aligns to 13:367/375 of 6iohA
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
39% identity, 90% coverage: 30:391/403 of query aligns to 13:365/366 of 6ioiA
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
36% identity, 87% coverage: 41:391/403 of query aligns to 21:350/350 of 2vavB
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
36% identity, 87% coverage: 41:389/403 of query aligns to 20:346/347 of 2vatA
>WP_012168760.1 NCBI__GCF_000010525.1:WP_012168760.1
MGETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEP
NADRSNAILVCHALTGDQHVANVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCM
GTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLGIERLFCVAGGSMGGMQVLQW
AASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVA
RMAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLY
VTRAMDYFDLAADYDGVLANAFRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVS
YAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPARTR
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory