Comparing WP_012169083.1 NCBI__GCF_000010525.1:WP_012169083.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
44% identity, 96% coverage: 13:386/390 of query aligns to 4:376/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
44% identity, 96% coverage: 13:385/390 of query aligns to 4:375/375 of 4pqaA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
43% identity, 93% coverage: 25:386/390 of query aligns to 16:376/377 of 7t1qA
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
39% identity, 96% coverage: 6:381/390 of query aligns to 1:375/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
39% identity, 95% coverage: 10:381/390 of query aligns to 1:371/377 of P44514
7lgpB Dape enzyme from shigella flexneri
41% identity, 97% coverage: 8:386/390 of query aligns to 1:377/377 of 7lgpB
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
50% identity, 45% coverage: 15:190/390 of query aligns to 6:180/265 of 4op4B
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
42% identity, 47% coverage: 8:190/390 of query aligns to 1:182/258 of 4h2kA
Sites not aligning to the query:
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
29% identity, 58% coverage: 62:287/390 of query aligns to 55:287/383 of 7uoiA
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
27% identity, 86% coverage: 19:352/390 of query aligns to 11:345/381 of 8uw6B
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
28% identity, 57% coverage: 4:225/390 of query aligns to 12:242/426 of 3pfoA
Sites not aligning to the query:
4mmoA The crystal structure of a m20 family metallo-carboxypeptidase sso-cp2 from sulfolobus solfataricus
27% identity, 55% coverage: 12:225/390 of query aligns to 2:218/437 of 4mmoA
3dljA Crystal structure of human carnosine dipeptidase 1
41% identity, 19% coverage: 75:149/390 of query aligns to 96:173/471 of 3dljA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
41% identity, 19% coverage: 75:149/390 of query aligns to 127:204/507 of Q96KN2
Sites not aligning to the query:
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
24% identity, 85% coverage: 53:384/390 of query aligns to 53:457/458 of 2pokA
Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human)
31% identity, 33% coverage: 22:148/390 of query aligns to 28:170/475 of Q96KP4
Sites not aligning to the query:
Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 2 papers)
36% identity, 22% coverage: 64:148/390 of query aligns to 81:170/475 of Q9D1A2
Sites not aligning to the query:
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
36% identity, 22% coverage: 64:148/390 of query aligns to 85:174/478 of 2zogA
Sites not aligning to the query:
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
36% identity, 22% coverage: 64:148/390 of query aligns to 85:174/478 of 2zofA
Sites not aligning to the query:
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
31% identity, 33% coverage: 80:208/390 of query aligns to 125:262/503 of Q8C165
Sites not aligning to the query:
>WP_012169083.1 NCBI__GCF_000010525.1:WP_012169083.1
MTDAAASTAVSDQALAFAKALIQAPSVTPDAGQALDVVADALKAAGYHVERLVFSTAGVP
VDNLYARIGTASPNLCFAGHVDVVPPGDAASWRHGPFSGAVEDGVLYGRGAVDMKGAVAA
FLAAALAYGAPAQGSLSFLITGDEEGPSIDGTAKVVDWLAAKGEVIDHCIVGEPTNPNAL
GDMVKIGRRGSLSGLITVEGRQGHVAYPHLADNPVPRLVRLLTALTAAPLDNGSAHFPPS
NLEVISVDVGNTAYNVIPGAATAKFNVRYNDLYSLESLMAEIARRLDTAGEPYVLTFRDG
ASESFLTAPGPFVETVLDAVADVTGQRPQMSTTGGTSDARFIKSLCPVVEFGLVGQTMHM
VNEATPVADLTALTAIYERLIARYFATFAA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory