Comparing WP_012275611.1 NCBI__GCF_000019185.1:WP_012275611.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 17 hits to proteins with known functional sites (download)
P36683 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Escherichia coli (strain K12) (see 2 papers)
81% identity, 100% coverage: 1:865/865 of query aligns to 1:865/865 of P36683
1l5jA Crystal structure of e. Coli aconitase b. (see paper)
81% identity, 100% coverage: 1:862/865 of query aligns to 1:862/862 of 1l5jA
4kp1A Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) (see paper)
27% identity, 51% coverage: 381:823/865 of query aligns to 1:420/423 of 4kp1A
4nqyA The reduced form of mj0499 (see paper)
26% identity, 51% coverage: 382:823/865 of query aligns to 1:407/409 of 4nqyA
P19414 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
26% identity, 40% coverage: 473:820/865 of query aligns to 163:502/778 of P19414
Sites not aligning to the query:
P39533 Homocitrate dehydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
25% identity, 43% coverage: 451:818/865 of query aligns to 138:505/789 of P39533
Sites not aligning to the query:
O14289 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
24% identity, 39% coverage: 488:826/865 of query aligns to 131:478/758 of O14289
Sites not aligning to the query:
P20004 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) (see 2 papers)
23% identity, 40% coverage: 473:820/865 of query aligns to 167:505/780 of P20004
Sites not aligning to the query:
8acnA Crystal structures of aconitase with isocitrate and nitroisocitrate bound (see paper)
23% identity, 40% coverage: 473:820/865 of query aligns to 139:477/753 of 8acnA
Sites not aligning to the query:
1fghA Complex with 4-hydroxy-trans-aconitate (see paper)
23% identity, 40% coverage: 473:820/865 of query aligns to 139:477/753 of 1fghA