Comparing WP_012334254.1 NCBI__GCF_000019365.1:WP_012334254.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 14 hits to proteins with known functional sites (download)
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
34% identity, 100% coverage: 2:325/325 of query aligns to 4:347/347 of 2i3gA
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
34% identity, 100% coverage: 2:325/325 of query aligns to 1:344/344 of 7npjB
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
34% identity, 100% coverage: 2:325/325 of query aligns to 1:344/344 of 7nphC
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
34% identity, 100% coverage: 2:325/325 of query aligns to 1:344/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
34% identity, 100% coverage: 2:325/325 of query aligns to 1:344/344 of 7nnrA
O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
28% identity, 97% coverage: 5:319/325 of query aligns to 6:338/344 of O50146
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
28% identity, 97% coverage: 5:319/325 of query aligns to 4:336/342 of 2ozpA
5einA Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
28% identity, 97% coverage: 5:319/325 of query aligns to 6:338/344 of 5einA
Q57658 Aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
27% identity, 53% coverage: 1:172/325 of query aligns to 7:196/354 of Q57658
Sites not aligning to the query:
1ys4A Structure of aspartate-semialdehyde dehydrogenase from methanococcus jannaschii (see paper)
27% identity, 53% coverage: 1:172/325 of query aligns to 1:190/348 of 1ys4A
Sites not aligning to the query:
4dpmA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with coa (see paper)
32% identity, 32% coverage: 2:104/325 of query aligns to 2:110/354 of 4dpmA
Sites not aligning to the query:
4dplA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with NADP (see paper)
32% identity, 32% coverage: 2:104/325 of query aligns to 2:110/354 of 4dplA
Sites not aligning to the query:
4dpkA Structure of malonyl-coenzyme a reductase from crenarchaeota (see paper)
32% identity, 32% coverage: 2:104/325 of query aligns to 2:110/354 of 4dpkA
Sites not aligning to the query:
4zicC Crystal structure of aspartate semialdehyde dehydrogenase with NADP from trichophyton rubrum (see paper)
25% identity, 56% coverage: 4:186/325 of query aligns to 3:199/357 of 4zicC
Sites not aligning to the query:
>WP_012334254.1 NCBI__GCF_000019365.1:WP_012334254.1
MSIRVGIVGISGFGGGEAMRLVASHPSFELIYAAGEGSAGSRLVDRFPGVPAKLADLVIE
KWDPVTLPKLDLLFASLPTGASAEALARVPEDVRIVDIGGDHRYVEGWAYGLADVWPAEI
EGRIRVANPGCFPAATLSALAPLLAERLIEPDNIVIDAKTGISGAGRGGADSKFGYAETN
ETVVPYGLLKHVHMPEIAKTIERLSGGSAAGLVFTPHLVPMTRGVLATMYCRGRASTGEC
LDAARRFYAGRAFVRVTDKPPQTKWATGSNLAFVSYAADPERNLVIAMGVVDNLGKGAAG
QAVQNANLICGLPETAGLDGLPVWP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory