Comparing WP_012334302.1 NCBI__GCF_000019365.1:WP_012334302.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
Q09179 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
49% identity, 97% coverage: 3:335/345 of query aligns to 27:358/359 of Q09179
P32288 Glutamine synthetase; GS; Glutamate--ammonia ligase; EC 6.3.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
47% identity, 95% coverage: 7:333/345 of query aligns to 27:352/370 of P32288
Sites not aligning to the query:
7cprA Glutamine synthetase from drosophila (see paper)
49% identity, 94% coverage: 8:333/345 of query aligns to 34:363/367 of 7cprA
Q8HZM5 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Canis lupus familiaris (Dog) (Canis familiaris) (see paper)
45% identity, 98% coverage: 3:339/345 of query aligns to 25:365/373 of Q8HZM5
2uu7A Crystal structure of apo glutamine synthetase from dog (canis familiaris) (see paper)
45% identity, 98% coverage: 3:339/345 of query aligns to 23:363/370 of 2uu7A
P15104 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Homo sapiens (Human) (see 4 papers)
45% identity, 98% coverage: 3:339/345 of query aligns to 25:365/373 of P15104
8ecyA Cryoem structure of bovine bestrophin-2 and glutamine synthetase complex (see paper)
45% identity, 98% coverage: 3:339/345 of query aligns to 24:364/371 of 8ecyA
2qc8A Crystal structure of human glutamine synthetase in complex with adp and methionine sulfoximine phosphate (see paper)
45% identity, 98% coverage: 3:339/345 of query aligns to 16:356/356 of 2qc8A
P15105 Glutamine synthetase; GS; Glutamate--ammonia ligase; Palmitoyltransferase GLUL; EC 6.3.1.2; EC 2.3.1.225 from Mus musculus (Mouse)
45% identity, 98% coverage: 3:339/345 of query aligns to 25:365/373 of P15105
Sites not aligning to the query:
Q9LVI8 Glutamine synthetase cytosolic isozyme 1-3; GS1; Glutamate--ammonia ligase GLN1;3; GLN1;3; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
45% identity, 96% coverage: 3:332/345 of query aligns to 18:350/354 of Q9LVI8
2d3cA Crystal structure of the maize glutamine synthetase complexed with adp and phosphinothricin phosphate (see paper)
45% identity, 96% coverage: 3:332/345 of query aligns to 16:348/353 of 2d3cA
2d3bA Crystal structure of the maize glutamine synthetase complexed with amppnp and methionine sulfoximine (see paper)
45% identity, 96% coverage: 3:332/345 of query aligns to 16:348/353 of 2d3bA
2d3aA Crystal structure of the maize glutamine synthetase complexed with adp and methionine sulfoximine phosphate (see paper)
45% identity, 96% coverage: 3:332/345 of query aligns to 16:348/353 of 2d3aA
Q9FMD9 Glutamine synthetase cytosolic isozyme 1-4; Glutamate--ammonia ligase GLN1;4; GLN1;4; EC 6.3.1.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
46% identity, 94% coverage: 7:332/345 of query aligns to 22:350/356 of Q9FMD9
2ojwA Crystal structure of human glutamine synthetase in complex with adp and phosphate (see paper)
44% identity, 98% coverage: 3:339/345 of query aligns to 26:360/360 of 2ojwA
7u5nA Cryo-em structure of glutamine synthetase (see paper)
41% identity, 98% coverage: 3:339/345 of query aligns to 24:336/343 of 7u5nA
8ooxB Glutamine synthetase (see paper)
25% identity, 83% coverage: 43:330/345 of query aligns to 49:345/438 of 8ooxB
8oozA Glutamine synthetase (see paper)
26% identity, 83% coverage: 43:330/345 of query aligns to 49:337/430 of 8oozA
8ooqB Glutamine synthetase from Methanothermococcus thermolithotrophicus (see paper)
28% identity, 83% coverage: 43:330/345 of query aligns to 55:354/446 of 8ooqB
Sites not aligning to the query:
8oooA Glutamine synthetase from methanothermococcus thermolithotrophicus in complex with 2-oxoglutarate and mgatp at 2.15 a resolution (see paper)
28% identity, 83% coverage: 43:330/345 of query aligns to 56:355/447 of 8oooA
Sites not aligning to the query:
>WP_012334302.1 NCBI__GCF_000019365.1:WP_012334302.1
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFDSFPTLEQLPLWGFDGSSTKQAEGHSSDCVL
KPVALYPDPARTNGALVMCEVMMPDGVTPHPTNKRATILDDEGAWFGFEQEYFLYKDGRP
LGFPASGYPAPQGPYYTGVGYKNVGDVARQIVEEHLDLCLAAGINHEGINAEVAKGQWEF
QIFGKGSKKAADEIWMARYLLLRLCEKYGVDIEWHCKPLGDTDWNGSGMHCNFSTKYMRE
VGGKAYFEALMAAFAKNLDDHIAVYGPDNHLRLTGKHETAPWNKFSYGVADRGASIRVPH
SFVKNDYKGYLEDRRPNSQGDPYQIASQVLKTISEVPTGAVSAAA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory