Comparing WP_012334742.1 NCBI__GCF_000019365.1:WP_012334742.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
31% identity, 87% coverage: 40:312/315 of query aligns to 59:332/347 of 2i3gA
Sites not aligning to the query:
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
31% identity, 87% coverage: 40:312/315 of query aligns to 56:329/344 of 7npjB
Sites not aligning to the query:
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
31% identity, 87% coverage: 40:312/315 of query aligns to 56:329/344 of 7nphC
Sites not aligning to the query:
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
31% identity, 87% coverage: 40:312/315 of query aligns to 56:329/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
31% identity, 87% coverage: 40:312/315 of query aligns to 56:329/344 of 7nnrA
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
27% identity, 67% coverage: 103:312/315 of query aligns to 123:327/342 of 2ozpA
Sites not aligning to the query:
O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
24% identity, 88% coverage: 35:312/315 of query aligns to 56:329/344 of O50146
Sites not aligning to the query:
>WP_012334742.1 NCBI__GCF_000019365.1:WP_012334742.1
MSRTATNRPSVFIDGEAGTTGLGIRERLEPSHEITLRSLPPAQRKDPDAKRALLAEVDLV
VLCLPDDAAKETVAMADALPGGGPRILDASTAHRVAPGWTYGFAELAPEQRAALRASRRV
ANPGCYPTGAIALLRPLVDAGLIPADHPISINAVSGYSGGGRKMIGAYEDGTAPAFELYG
LGFAHKHLPETQAYSRLTRRPIFVPSVGNFRQGMLVSIPLHLDALPGRPHPGDLEQALAA
RYAGEELVRVVTGAEEGAHRERLEPEALNGTDGLELRVFGSDAHGQAVLVARLDNLGKGA
SGAAVQNLRLMLDLA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory